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P77965

- RPOB_SYNY3

UniProt

P77965 - RPOB_SYNY3

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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. DNA-directed RNA polymerase activity Source: UniProtKB-HAMAP
  3. ribonucleoside binding Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:sll1787
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11021102DNA-directed RNA polymerase subunit betaPRO_0000047982Add
BLAST

Proteomic databases

PaxDbiP77965.
PRIDEiP77965.

Interactioni

Subunit structurei

In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

DIPiDIP-37767N.
IntActiP77965. 9 interactions.
STRINGi1148.sll1787.

Structurei

3D structure databases

ProteinModelPortaliP77965.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0085.
HOGENOMiHOG000218611.
InParanoidiP77965.
KOiK03043.
OMAiRKNEGLY.
OrthoDBiEOG6M9DS6.
PhylomeDBiP77965.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77965-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTNLATTMLP DLIEIQHASF HWFLEEGLIE ELNSFSPISD YTGKLELHFL
60 70 80 90 100
GKDYKLKQPK YDVDESKRRD ASYSVQMYVP TRLINKETGE IKEQEVFIGD
110 120 130 140 150
LPLMTERGTF IINGAERVIV NQIVRSPGVY YKKELDKNGR RTYSASLIPN
160 170 180 190 200
RGAWLKFETD KNGLVYVRID KTRKLSAQVL LKAIGLSDNE ILDSLSHPEF
210 220 230 240 250
YQKTLDKEGN PTEEEALVEL YKKLRPGEPP TVSGGQQLLE SRFFDPKRYD
260 270 280 290 300
LGRVGRYKLN KKLRLNEADT TRVLTPQDIL AAINYLINLE FDVGTTDDID
310 320 330 340 350
HLGNRRVRSV GELLQNQIRV GLNRLERIIR ERMTVSESDA LTPASLVNPK
360 370 380 390 400
PLVAAIKEFF GSSQLSQFMD QTNPLAELTH KRRISALGPG GLTRERAGFA
410 420 430 440 450
VRDIHPSHHG RICPVETPEG PNAGLIGSLA TCARVNDYGF IETPYFRVES
460 470 480 490 500
GRVRKDLDPV YLTADEEDDM RVAPGDIPTD EEGNIIGESV PIRYRQEFST
510 520 530 540 550
TSPEQVDYVA VSPVQIISVA TSMIPFLEHD DANRALMGSN MQRQAVPLLR
560 570 580 590 600
PERPLVGTGL EAQAARDSGM VIVSRTHGIV TYVDATEIRV QPHSPDNPAE
610 620 630 640 650
KGEEIVYPIQ KYQRSNQDTC LNQRPLVYAG EDVVPGQVLA DGSATEGGEL
660 670 680 690 700
ALGQNILVAY MPWEGYNYED AILISERLVY DDVYTSIHIE KFEIEARQTK
710 720 730 740 750
LGPEEITREI PNVGEDALRN LDEHGIIRIG AWVESGDILV GKVTPKGEAD
760 770 780 790 800
QPPEEKLLRA IFGEKARDVR DNSLRVPNGE KGRVVDVRVF TREKGDELPP
810 820 830 840 850
GANMVVRIYV AQKRKIQVGD KMAGRHGNKG IISRILPIED MPYLPDGRPI
860 870 880 890 900
DIALNPLGVP SRMNVGQVFE CLLGWAGENL GVRFKITPFD EMYGEEASRD
910 920 930 940 950
TVHGLLEEAS QRPNKDWVFN ENHPGKIQVF DGRTGEPFDR PITVGQAYML
960 970 980 990 1000
KLVHLVDDKI HARSTGPYSL VTQQPLGGKA QQGGQRFGEM EVWALEAYGA
1010 1020 1030 1040 1050
AYILQELLTV KSDDMQGRNE ALNAIVKGKS IPRPGTPESF KVLMRELQSL
1060 1070 1080 1090 1100
GLDIAAHKVQ LSEDGESADA EVDLMIDSQR RAPNRPTYES LHTEEDLEEE

EV
Length:1,102
Mass (Da):123,365
Last modified:February 1, 1997 - v1
Checksum:i40235F5EBA7CE881
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA17365.1.
PIRiS77518.
RefSeqiNP_440685.1. NC_000911.1.
YP_005650744.1. NC_017277.1.
YP_007450568.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17365; BAA17365; BAA17365.
GeneIDi953988.
KEGGisyn:sll1787.
PATRICi23838578. VBISynSp132158_0856.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA17365.1 .
PIRi S77518.
RefSeqi NP_440685.1. NC_000911.1.
YP_005650744.1. NC_017277.1.
YP_007450568.1. NC_020286.1.

3D structure databases

ProteinModelPortali P77965.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-37767N.
IntActi P77965. 9 interactions.
STRINGi 1148.sll1787.

Proteomic databases

PaxDbi P77965.
PRIDEi P77965.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA17365 ; BAA17365 ; BAA17365 .
GeneIDi 953988.
KEGGi syn:sll1787.
PATRICi 23838578. VBISynSp132158_0856.

Phylogenomic databases

eggNOGi COG0085.
HOGENOMi HOG000218611.
InParanoidi P77965.
KOi K03043.
OMAi RKNEGLY.
OrthoDBi EOG6M9DS6.
PhylomeDBi P77965.

Family and domain databases

Gene3Di 2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPi MF_01321. RNApol_bact_RpoB.
InterProi IPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view ]
PANTHERi PTHR20856. PTHR20856. 1 hit.
Pfami PF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02013. rpoB. 1 hit.
PROSITEi PS01166. RNA_POL_BETA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiRPOB_SYNY3
AccessioniPrimary (citable) accession number: P77965
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 26, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3