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P77965 (RPOB_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta
Short name=RNAP subunit beta
EC=2.7.7.6
Alternative name(s):
RNA polymerase subunit beta
Transcriptase subunit beta
Gene names
Name:rpoB
Ordered Locus Names:sll1787
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis ›

Protein attributes

Sequence length1102 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP-Rule MF_01321

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_01321

Subunit structure

In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Sequence similarities

Belongs to the RNA polymerase beta chain family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11021102DNA-directed RNA polymerase subunit beta HAMAP-Rule MF_01321
PRO_0000047982

Sequences

Sequence LengthMass (Da)Tools
P77965 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 40235F5EBA7CE881

FASTA1,102123,365
        10         20         30         40         50         60 
MTNLATTMLP DLIEIQHASF HWFLEEGLIE ELNSFSPISD YTGKLELHFL GKDYKLKQPK 

        70         80         90        100        110        120 
YDVDESKRRD ASYSVQMYVP TRLINKETGE IKEQEVFIGD LPLMTERGTF IINGAERVIV 

       130        140        150        160        170        180 
NQIVRSPGVY YKKELDKNGR RTYSASLIPN RGAWLKFETD KNGLVYVRID KTRKLSAQVL 

       190        200        210        220        230        240 
LKAIGLSDNE ILDSLSHPEF YQKTLDKEGN PTEEEALVEL YKKLRPGEPP TVSGGQQLLE 

       250        260        270        280        290        300 
SRFFDPKRYD LGRVGRYKLN KKLRLNEADT TRVLTPQDIL AAINYLINLE FDVGTTDDID 

       310        320        330        340        350        360 
HLGNRRVRSV GELLQNQIRV GLNRLERIIR ERMTVSESDA LTPASLVNPK PLVAAIKEFF 

       370        380        390        400        410        420 
GSSQLSQFMD QTNPLAELTH KRRISALGPG GLTRERAGFA VRDIHPSHHG RICPVETPEG 

       430        440        450        460        470        480 
PNAGLIGSLA TCARVNDYGF IETPYFRVES GRVRKDLDPV YLTADEEDDM RVAPGDIPTD 

       490        500        510        520        530        540 
EEGNIIGESV PIRYRQEFST TSPEQVDYVA VSPVQIISVA TSMIPFLEHD DANRALMGSN 

       550        560        570        580        590        600 
MQRQAVPLLR PERPLVGTGL EAQAARDSGM VIVSRTHGIV TYVDATEIRV QPHSPDNPAE 

       610        620        630        640        650        660 
KGEEIVYPIQ KYQRSNQDTC LNQRPLVYAG EDVVPGQVLA DGSATEGGEL ALGQNILVAY 

       670        680        690        700        710        720 
MPWEGYNYED AILISERLVY DDVYTSIHIE KFEIEARQTK LGPEEITREI PNVGEDALRN 

       730        740        750        760        770        780 
LDEHGIIRIG AWVESGDILV GKVTPKGEAD QPPEEKLLRA IFGEKARDVR DNSLRVPNGE 

       790        800        810        820        830        840 
KGRVVDVRVF TREKGDELPP GANMVVRIYV AQKRKIQVGD KMAGRHGNKG IISRILPIED 

       850        860        870        880        890        900 
MPYLPDGRPI DIALNPLGVP SRMNVGQVFE CLLGWAGENL GVRFKITPFD EMYGEEASRD 

       910        920        930        940        950        960 
TVHGLLEEAS QRPNKDWVFN ENHPGKIQVF DGRTGEPFDR PITVGQAYML KLVHLVDDKI 

       970        980        990       1000       1010       1020 
HARSTGPYSL VTQQPLGGKA QQGGQRFGEM EVWALEAYGA AYILQELLTV KSDDMQGRNE 

      1030       1040       1050       1060       1070       1080 
ALNAIVKGKS IPRPGTPESF KVLMRELQSL GLDIAAHKVQ LSEDGESADA EVDLMIDSQR 

      1090       1100 
RAPNRPTYES LHTEEDLEEE EV

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References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000022 Genomic DNA. Translation: BAA17365.1.
PIRS77518.
RefSeqNP_440685.1. NC_000911.1.
YP_005650744.1. NC_017277.1.
YP_007450568.1. NC_020286.1.

3D structure databases

ProteinModelPortalP77965.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-37767N.
IntActP77965. 9 interactions.
STRING1148.sll1787.

Proteomic databases

PaxDbP77965.
PRIDEP77965.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA17365; BAA17365; BAA17365.
GeneID12256436.
14616218.
953988.
KEGGsyn:sll1787.
syy:SYNGTS_0791.
PATRIC23838578. VBISynSp132158_0856.

Phylogenomic databases

eggNOGCOG0085.
HOGENOMHOG000218611.
KOK03043.
OMAFMTWEGY.
ProtClustDBPRK00405.

Family and domain databases

Gene3D2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
HAMAPMF_01321. RNApol_bact_RpoB.
InterProIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERPTHR20856. PTHR20856. 1 hit.
PTHR20856:SF3. PTHR20856:SF3. 1 hit.
PfamPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsTIGR02013. rpoB. 1 hit.
PROSITEPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRPOB_SYNY3
AccessionPrimary (citable) accession number: P77965
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 1, 2013
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

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