Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P77947

- MASY_STRAE

UniProt

P77947 - MASY_STRAE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Malate synthase

Gene

aceB

Organism
Streptomyces arenae
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.

Pathwayi

GO - Molecular functioni

  1. malate synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-UniPathway
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Glyoxylate bypass, Tricarboxylic acid cycle

Enzyme and pathway databases

UniPathwayiUPA00703; UER00720.

Names & Taxonomyi

Protein namesi
Recommended name:
Malate synthase (EC:2.3.3.9)
Gene namesi
Name:aceB
OrganismiStreptomyces arenae
Taxonomic identifieri29301 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 543543Malate synthasePRO_0000166877Add
BLAST

Interactioni

Subunit structurei

Homodimer.

Structurei

3D structure databases

ProteinModelPortaliP77947.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the malate synthase family.Curated

Family and domain databases

InterProiIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PfamiPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF001363. Malate_synth. 1 hit.
SUPFAMiSSF51645. SSF51645. 1 hit.
TIGRFAMsiTIGR01344. malate_syn_A. 1 hit.
PROSITEiPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77947-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSAPAPSPLA IVDAEPLPRQ EEVLTDAALA FVAELLHRRF TRAVTNSSPR
60 70 80 90 100
RADAAREIAR TSTLDFLPET AAVRADDSWR VAGPAALNDR RVEITGPTDR
110 120 130 140 150
KMTINALNSG AKVWLADFEE PSAPTWENVV LGQVNLSDAY TRNIDFTDER
160 170 180 190 200
TGKTYALRPL KSWRPSSWPR GWHLNERHLV DPDGSFGARR VVVDFGLYFF
210 220 230 240 250
HNAQRLLDLG KGPYFYLPKT ESHLEARLWN DVFVFAQDYV GIPQGTVRAT
260 270 280 290 300
VLIETITAAY EMEEILYELR DHASGLNAGR WDYLFSIVKN FPATRPKFVL
310 320 330 340 350
PDRNVTMTKL TMTAFMRRYT NCSSYCHNAR ASAAIGGMAA FIPSRDAEVN
360 370 380 390 400
KVAFEKVRAD KDREANDGFD GSWVAHPDLV PIAMESFDRC WHRPNQKDRL
410 420 430 440 450
REDVHVEAAD LIAVDSLEAT TYAGSSSTAV QVGIRYIEAW LRGLGRVAIF
460 470 480 490 500
NLMEDAATAE ISRSQIWQWI NAGVEFEHGE KATPIWPRKS RRGRKWRPVR
510 520 530 540
EELGEEPFAA RDWQHAHDLV VQVSLDEDYA DFLTLPAYER LRG
Length:543
Mass (Da):61,408
Last modified:February 1, 1997 - v1
Checksum:i60829A40F62A0D85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U63518 Genomic DNA. Translation: AAB53938.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U63518 Genomic DNA. Translation: AAB53938.1 .

3D structure databases

ProteinModelPortali P77947.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00703 ; UER00720 .

Family and domain databases

InterProi IPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view ]
Pfami PF01274. Malate_synthase. 1 hit.
[Graphical view ]
PIRSFi PIRSF001363. Malate_synth. 1 hit.
SUPFAMi SSF51645. SSF51645. 1 hit.
TIGRFAMsi TIGR01344. malate_syn_A. 1 hit.
PROSITEi PS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Gene cloning and sequencing, and enzyme purification of the malate synthase of Streptomyces arenae."
    Huettner S., Mecke D., Froehlich K.-U.
    Gene 188:239-246(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
    Strain: Tu469.

Entry informationi

Entry nameiMASY_STRAE
AccessioniPrimary (citable) accession number: P77947
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: October 29, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3