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P77947

- MASY_STRAE

UniProt

P77947 - MASY_STRAE

Protein

Malate synthase

Gene

aceB

Organism
Streptomyces arenae
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.

    Pathwayi

    GO - Molecular functioni

    1. malate synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-UniPathway
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Glyoxylate bypass, Tricarboxylic acid cycle

    Enzyme and pathway databases

    UniPathwayiUPA00703; UER00720.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Malate synthase (EC:2.3.3.9)
    Gene namesi
    Name:aceB
    OrganismiStreptomyces arenae
    Taxonomic identifieri29301 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 543543Malate synthasePRO_0000166877Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.

    Structurei

    3D structure databases

    ProteinModelPortaliP77947.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the malate synthase family.Curated

    Family and domain databases

    InterProiIPR011076. Malate_synth-like.
    IPR006252. Malate_synthA.
    IPR001465. Malate_synthase.
    IPR019830. Malate_synthase_CS.
    [Graphical view]
    PfamiPF01274. Malate_synthase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001363. Malate_synth. 1 hit.
    SUPFAMiSSF51645. SSF51645. 1 hit.
    TIGRFAMsiTIGR01344. malate_syn_A. 1 hit.
    PROSITEiPS00510. MALATE_SYNTHASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P77947-1 [UniParc]FASTAAdd to Basket

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    MSAPAPSPLA IVDAEPLPRQ EEVLTDAALA FVAELLHRRF TRAVTNSSPR    50
    RADAAREIAR TSTLDFLPET AAVRADDSWR VAGPAALNDR RVEITGPTDR 100
    KMTINALNSG AKVWLADFEE PSAPTWENVV LGQVNLSDAY TRNIDFTDER 150
    TGKTYALRPL KSWRPSSWPR GWHLNERHLV DPDGSFGARR VVVDFGLYFF 200
    HNAQRLLDLG KGPYFYLPKT ESHLEARLWN DVFVFAQDYV GIPQGTVRAT 250
    VLIETITAAY EMEEILYELR DHASGLNAGR WDYLFSIVKN FPATRPKFVL 300
    PDRNVTMTKL TMTAFMRRYT NCSSYCHNAR ASAAIGGMAA FIPSRDAEVN 350
    KVAFEKVRAD KDREANDGFD GSWVAHPDLV PIAMESFDRC WHRPNQKDRL 400
    REDVHVEAAD LIAVDSLEAT TYAGSSSTAV QVGIRYIEAW LRGLGRVAIF 450
    NLMEDAATAE ISRSQIWQWI NAGVEFEHGE KATPIWPRKS RRGRKWRPVR 500
    EELGEEPFAA RDWQHAHDLV VQVSLDEDYA DFLTLPAYER LRG 543
    Length:543
    Mass (Da):61,408
    Last modified:February 1, 1997 - v1
    Checksum:i60829A40F62A0D85
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U63518 Genomic DNA. Translation: AAB53938.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U63518 Genomic DNA. Translation: AAB53938.1 .

    3D structure databases

    ProteinModelPortali P77947.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00703 ; UER00720 .

    Family and domain databases

    InterProi IPR011076. Malate_synth-like.
    IPR006252. Malate_synthA.
    IPR001465. Malate_synthase.
    IPR019830. Malate_synthase_CS.
    [Graphical view ]
    Pfami PF01274. Malate_synthase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001363. Malate_synth. 1 hit.
    SUPFAMi SSF51645. SSF51645. 1 hit.
    TIGRFAMsi TIGR01344. malate_syn_A. 1 hit.
    PROSITEi PS00510. MALATE_SYNTHASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Gene cloning and sequencing, and enzyme purification of the malate synthase of Streptomyces arenae."
      Huettner S., Mecke D., Froehlich K.-U.
      Gene 188:239-246(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
      Strain: Tu469.

    Entry informationi

    Entry nameiMASY_STRAE
    AccessioniPrimary (citable) accession number: P77947
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3