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Protein

Cytochrome c oxidase subunit 4

Gene

ctaH

Organism
Paracoccus denitrificans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Not required for enzymatic activity or proton pumping of the cytochrome c oxidase complex.1 Publication

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 4 (EC:1.9.3.1)
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene namesi
Name:ctaH
OrganismiParacoccus denitrificans
Taxonomic identifieri266 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini2 – 17CytoplasmicAdd BLAST16
Transmembranei18 – 49HelicalAdd BLAST32
Topological domaini50Periplasmic1

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001839042 – 50Cytochrome c oxidase subunit 4Add BLAST49

Structurei

Secondary structure

150
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi18 – 47Combined sources30

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QLEX-ray3.00D8-50[»]
ProteinModelPortaliP77921.
SMRiP77921.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP77921.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.5.160. 1 hit.
InterProiView protein in InterPro
IPR012422. Cyt_c_oxidase_su4_bac-aa3.
PfamiView protein in Pfam
PF07835. COX4_pro_2. 1 hit.
SUPFAMiSSF81469. SSF81469. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P77921-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASHHEITDH KHGEMDIRHQ QATFAGFIKG ATWVSILSIA VLVFLALANS
Length:50
Mass (Da):5,501
Last modified:January 23, 2007 - v3
Checksum:i1D6B6674CAF5EC88
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y08372 Genomic DNA. Translation: CAA69659.1.
RefSeqiWP_041529744.1. NZ_FOYK01000011.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiCOX4_PARDE
AccessioniPrimary (citable) accession number: P77921
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 23, 2007
Last modified: July 5, 2017
This is version 89 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references