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P77921

- COX4_PARDE

UniProt

P77921 - COX4_PARDE

Protein

Cytochrome c oxidase subunit 4

Gene

ctaH

Organism
Paracoccus denitrificans
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Not required for enzymatic activity or proton pumping of the cytochrome c oxidase complex.1 Publication

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 4 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 4
    Cytochrome c oxidase polypeptide IV
    Gene namesi
    Name:ctaH
    OrganismiParacoccus denitrificans
    Taxonomic identifieri266 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 5049Cytochrome c oxidase subunit 4PRO_0000183904Add
    BLAST

    Structurei

    Secondary structure

    1
    50
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi18 – 4730

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1QLEX-ray3.00D8-50[»]
    ProteinModelPortaliP77921.
    SMRiP77921. Positions 8-50.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP77921.

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini2 – 1716CytoplasmicAdd
    BLAST
    Topological domaini50 – 501Periplasmic

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei18 – 4932HelicalAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Family and domain databases

    Gene3Di1.20.5.160. 1 hit.
    InterProiIPR012422. Cyt_c_oxidase_su4_bac-aa3.
    [Graphical view]
    PfamiPF07835. COX4_pro_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF81469. SSF81469. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P77921-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASHHEITDH KHGEMDIRHQ QATFAGFIKG ATWVSILSIA VLVFLALANS   50
    Length:50
    Mass (Da):5,501
    Last modified:January 23, 2007 - v3
    Checksum:i1D6B6674CAF5EC88
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y08372 Genomic DNA. Translation: CAA69659.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y08372 Genomic DNA. Translation: CAA69659.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1QLE X-ray 3.00 D 8-50 [» ]
    ProteinModelPortali P77921.
    SMRi P77921. Positions 8-50.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei P77921.

    Family and domain databases

    Gene3Di 1.20.5.160. 1 hit.
    InterProi IPR012422. Cyt_c_oxidase_su4_bac-aa3.
    [Graphical view ]
    Pfami PF07835. COX4_pro_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81469. SSF81469. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Isolation, analysis, and deletion of the gene coding for subunit IV of cytochrome c oxidase in Paracoccus denitrificans."
      Witt H., Ludwig B.
      J. Biol. Chem. 272:5514-5517(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION.
      Strain: Pd 1222.
    2. "Thermodynamic and structural stability of cytochrome c oxidase from Paracoccus denitrificans."
      Haltia T., Semo N., Arrondo J.L., Goni F.M., Freire E.
      Biochemistry 33:9731-9740(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-32.
    3. "Structure at 2.8-A resolution of cytochrome c oxidase from Paracoccus denitrificans."
      Iwata S., Ostermeier C., Ludwig B., Michel H.
      Nature 376:660-669(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS).

    Entry informationi

    Entry nameiCOX4_PARDE
    AccessioniPrimary (citable) accession number: P77921
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 76 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3