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P77919 (PYRI_PYRAB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aspartate carbamoyltransferase regulatory chain
Gene names
Name:pyrI
Ordered Locus Names:PYRAB13260
ORF Names:PAB1499
OrganismPyrococcus abyssi (strain GE5 / Orsay) [Complete proteome] [HAMAP]
Taxonomic identifier272844 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length152 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in allosteric regulation of aspartate carbamoyltransferase By similarity. HAMAP-Rule MF_00002

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00002

Subunit structure

Contains catalytic and regulatory chains By similarity. HAMAP-Rule MF_00002

Sequence similarities

Belongs to the PyrI family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 152152Aspartate carbamoyltransferase regulatory chain HAMAP-Rule MF_00002
PRO_0000142337

Sites

Metal binding1081Zinc By similarity
Metal binding1131Zinc By similarity
Metal binding1361Zinc By similarity
Metal binding1391Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
P77919 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 05DEE2DD0839A384

FASTA15216,958
        10         20         30         40         50         60 
MAELKVSAIK EGTVIDHIPA GKGLKVIEIL KLGKLTNGGA VLLAMNVPSK KLGRKDIVKV 

        70         80         90        100        110        120 
EGRFLSEEEV NKIALVAPNA TVNIIRDYKV VEKFKVEVPD VIEGILRCGN PNCITNHEYV 

       130        140        150 
TTKFYVISRE PLKVRCHYCE RTMEEEEILA NL 

« Hide

References

« Hide 'large scale' references
[1]"Aspartate transcarbamylase from the deep-sea hyperthermophilic archaeon Pyrococcus abyssi: genetic organization, structure, and expression in Escherichia coli."
Purcarea C., Herve G., Ladjimi M.M., Cunin R.
J. Bacteriol. 179:4143-4157(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: GE5 / Orsay.
[2]"An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi."
Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O., Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.
Mol. Microbiol. 47:1495-1512(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GE5 / Orsay.
[3]"Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
Gao J., Wang J.
Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: GE5 / Orsay.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U61765 Genomic DNA. Translation: AAB62985.1.
AJ248287 Genomic DNA. Translation: CAB50231.1.
HE613800 Genomic DNA. Translation: CCE70768.1.
PIRB75042.
RefSeqNP_127001.1. NC_000868.1.

3D structure databases

ProteinModelPortalP77919.
SMRP77919. Positions 5-146.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272844.PAB1499.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB50231; CAB50231; PAB1499.
GeneID1496714.
KEGGpab:PAB1499.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1781.
HOGENOMHOG000113530.
KOK00610.
OMANPNCISN.
ProtClustDBPRK00893.

Family and domain databases

Gene3D2.30.30.20. 1 hit.
3.30.70.140. 1 hit.
HAMAPMF_00002. Asp_carb_tr_reg.
InterProIPR020545. Asp_carbamoyltransf_reg_N.
IPR002801. Asp_carbamoylTrfase_reg.
IPR020542. Asp_carbamoyltrfase_reg_C.
[Graphical view]
PfamPF01948. PyrI. 1 hit.
PF02748. PyrI_C. 1 hit.
[Graphical view]
ProDomPD006194. Asp_carbamoylTrfase_reg. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF54893. SSF54893. 1 hit.
SSF57825. SSF57825. 1 hit.
TIGRFAMsTIGR00240. ATCase_reg. 1 hit.
ProtoNetSearch...

Entry information

Entry namePYRI_PYRAB
AccessionPrimary (citable) accession number: P77919
Secondary accession number(s): G8ZHD1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: February 19, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families