SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P77919

- PYRI_PYRAB

UniProt

P77919 - PYRI_PYRAB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Aspartate carbamoyltransferase regulatory chain

Gene
pyrI, PYRAB13260, PAB1499
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Involved in allosteric regulation of aspartate carbamoyltransferase By similarity.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi108 – 1081Zinc By similarity
Metal bindingi113 – 1131Zinc By similarity
Metal bindingi136 – 1361Zinc By similarity
Metal bindingi139 – 1391Zinc By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
  2. pyrimidine nucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Pyrimidine biosynthesis

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate carbamoyltransferase regulatory chain
Gene namesi
Name:pyrI
Ordered Locus Names:PYRAB13260
ORF Names:PAB1499
OrganismiPyrococcus abyssi (strain GE5 / Orsay)
Taxonomic identifieri272844 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000000810: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. aspartate carbamoyltransferase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 152152Aspartate carbamoyltransferase regulatory chainUniRule annotationPRO_0000142337Add
BLAST

Interactioni

Subunit structurei

Contains catalytic and regulatory chains By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi272844.PAB1499.

Structurei

3D structure databases

ProteinModelPortaliP77919.
SMRiP77919. Positions 5-146.

Family & Domainsi

Sequence similaritiesi

Belongs to the PyrI family.

Phylogenomic databases

eggNOGiCOG1781.
HOGENOMiHOG000113530.
KOiK00610.
OMAiCITSIEQ.

Family and domain databases

Gene3Di2.30.30.20. 1 hit.
3.30.70.140. 1 hit.
HAMAPiMF_00002. Asp_carb_tr_reg.
InterProiIPR020545. Asp_carbamoyltransf_reg_N.
IPR002801. Asp_carbamoylTrfase_reg.
IPR020542. Asp_carbamoyltrfase_reg_C.
[Graphical view]
PfamiPF01948. PyrI. 1 hit.
PF02748. PyrI_C. 1 hit.
[Graphical view]
ProDomiPD006194. Asp_carbamoylTrfase_reg. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54893. SSF54893. 1 hit.
SSF57825. SSF57825. 1 hit.
TIGRFAMsiTIGR00240. ATCase_reg. 1 hit.

Sequencei

Sequence statusi: Complete.

P77919-1 [UniParc]FASTAAdd to Basket

« Hide

MAELKVSAIK EGTVIDHIPA GKGLKVIEIL KLGKLTNGGA VLLAMNVPSK    50
KLGRKDIVKV EGRFLSEEEV NKIALVAPNA TVNIIRDYKV VEKFKVEVPD 100
VIEGILRCGN PNCITNHEYV TTKFYVISRE PLKVRCHYCE RTMEEEEILA 150
NL 152
Length:152
Mass (Da):16,958
Last modified:February 1, 1997 - v1
Checksum:i05DEE2DD0839A384
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U61765 Genomic DNA. Translation: AAB62985.1.
AJ248287 Genomic DNA. Translation: CAB50231.1.
HE613800 Genomic DNA. Translation: CCE70768.1.
PIRiB75042.
RefSeqiNP_127001.1. NC_000868.1.
WP_010868441.1. NC_000868.1.

Genome annotation databases

EnsemblBacteriaiCAB50231; CAB50231; PAB1499.
GeneIDi1496714.
KEGGipab:PAB1499.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U61765 Genomic DNA. Translation: AAB62985.1 .
AJ248287 Genomic DNA. Translation: CAB50231.1 .
HE613800 Genomic DNA. Translation: CCE70768.1 .
PIRi B75042.
RefSeqi NP_127001.1. NC_000868.1.
WP_010868441.1. NC_000868.1.

3D structure databases

ProteinModelPortali P77919.
SMRi P77919. Positions 5-146.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272844.PAB1499.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB50231 ; CAB50231 ; PAB1499 .
GeneIDi 1496714.
KEGGi pab:PAB1499.

Phylogenomic databases

eggNOGi COG1781.
HOGENOMi HOG000113530.
KOi K00610.
OMAi CITSIEQ.

Family and domain databases

Gene3Di 2.30.30.20. 1 hit.
3.30.70.140. 1 hit.
HAMAPi MF_00002. Asp_carb_tr_reg.
InterProi IPR020545. Asp_carbamoyltransf_reg_N.
IPR002801. Asp_carbamoylTrfase_reg.
IPR020542. Asp_carbamoyltrfase_reg_C.
[Graphical view ]
Pfami PF01948. PyrI. 1 hit.
PF02748. PyrI_C. 1 hit.
[Graphical view ]
ProDomi PD006194. Asp_carbamoylTrfase_reg. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF54893. SSF54893. 1 hit.
SSF57825. SSF57825. 1 hit.
TIGRFAMsi TIGR00240. ATCase_reg. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Aspartate transcarbamylase from the deep-sea hyperthermophilic archaeon Pyrococcus abyssi: genetic organization, structure, and expression in Escherichia coli."
    Purcarea C., Herve G., Ladjimi M.M., Cunin R.
    J. Bacteriol. 179:4143-4157(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: GE5 / Orsay.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GE5 / Orsay.
  3. "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and Pyrococcus furiosus DSM 3638."
    Gao J., Wang J.
    Curr. Microbiol. 64:118-129(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: GE5 / Orsay.

Entry informationi

Entry nameiPYRI_PYRAB
AccessioniPrimary (citable) accession number: P77919
Secondary accession number(s): G8ZHD1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: September 3, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi