P77892 (SYGA_MORCA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:

glyQ

Organism

Moraxella catarrhalis

Taxonomic identifier

480 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Moraxella › Branhamella

Protein attributes

Sequence length	318 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP-Rule MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Gene Ontology (GO)
Biological_process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 318	318	Glycine--tRNA ligase alpha subunit HAMAP-Rule MF_00254		PRO_0000072849

Sequences

	Sequence		Length	Mass (Da)
	P77892 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: B34405FD84F06768	FASTA	318	36,235
	10 20 30 40 50 60 MDSGETLTFQ ALILTLQNYW ASRGCVVLQP YDMEVGAGTF HTATFLRALT PERWNTAYVQ 70 80 90 100 110 120 PSRRPTDGRY GDNPNRLQHY YQFQVVLKPN PANIQELYLG SLKAIGIDTL THDVRFVEDN 130 140 150 160 170 180 WESPTLGAWG LGWEVWLNGM EVTQFTYFQQ VGGIECFPVT GEITYGLERL AMYIQGVDSV 190 200 210 220 230 240 YDLVWADGEF GRVTYGDVFH QNEVEQSAYN FEHADVAKLF ELFDFYEEQA DKLVAVNLPL 250 260 270 280 290 300 PAYEMVLKAS HAFNLLDARG AISVTERQRF ILRVRTLARK VAISYTEARA KLGFPLADDA 310 HKAEALEKWL PKEPKIIL

References

[1]	Walker E.S., Preston R.A., Post J.C., Ehrlich G.D., Klingman K.L. Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 25238 / DSM 9143 / NCTC 11020.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U73324 Genomic DNA. Translation: AAB18211.1.
3D structure databases
ProteinModelPortal	P77892.
SMR	P77892. Positions 7-290.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha.
InterPro	IPR006194. Gly-tRNA-synth_heterodimer. IPR002310. Gly-tRNA_ligase_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_MORCA

Accession

Primary (citable) accession number: P77892

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	May 29, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program