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Protein

Probable cation-transporting ATPase HI_0290

Gene

HI_0290

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi20PROSITE-ProRule annotation1
Metal bindingi23PROSITE-ProRule annotation1
Active sitei4224-aspartylphosphate intermediateBy similarity1
Metal bindingi617MagnesiumPROSITE-ProRule annotation1
Metal bindingi621MagnesiumPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cation-transporting ATPase HI_0290 (EC:3.6.3.-)
Gene namesi
Ordered Locus Names:HI_0290
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei94 – 114HelicalSequence analysisAdd BLAST21
Transmembranei118 – 138HelicalSequence analysisAdd BLAST21
Transmembranei157 – 177HelicalSequence analysisAdd BLAST21
Transmembranei180 – 200HelicalSequence analysisAdd BLAST21
Transmembranei340 – 360HelicalSequence analysisAdd BLAST21
Transmembranei373 – 393HelicalSequence analysisAdd BLAST21
Transmembranei523 – 543HelicalSequence analysisAdd BLAST21
Transmembranei608 – 628HelicalSequence analysisAdd BLAST21
Transmembranei675 – 695HelicalSequence analysisAdd BLAST21
Transmembranei697 – 717HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000463341 – 722Probable cation-transporting ATPase HI_0290Add BLAST722

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0290.

Structurei

3D structure databases

ProteinModelPortaliP77868.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 76HMAPROSITE-ProRule annotationAdd BLAST67

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C59. Bacteria.
COG2217. LUCA.
KOiK17686.
OMAiHIFGGPL.
PhylomeDBiP77868.

Family and domain databases

CDDicd00371. HMA. 1 hit.
Gene3Di3.40.1110.10. 1 hit.
InterProiView protein in InterPro
IPR023299. ATPase_P-typ_cyto_dom_N.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom_sf.
IPR008250. ATPase_P-typ_transduc_dom_A_sf.
IPR036412. HAD-like_sf.
IPR017969. Heavy-metal-associated_CS.
IPR006121. HMA_dom.
IPR036163. HMA_dom_sf.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
PfamiView protein in Pfam
PF00403. HMA. 1 hit.
SUPFAMiSSF55008. SSF55008. 1 hit.
SSF56784. SSF56784. 2 hits.
SSF81653. SSF81653. 1 hit.
SSF81660. SSF81660. 1 hit.
SSF81665. SSF81665. 3 hits.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiView protein in PROSITE
PS00154. ATPASE_E1_E2. 1 hit.
PS01047. HMA_1. 1 hit.
PS50846. HMA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P77868-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDLTPQSKK ISIQIGGMTC QSCANRIEKV LNKKPFVQQA GVNFAAEEAQ
60 70 80 90 100
VVFDATQASE AQIIEIIHKT GFSAHIKQAN ELPIEENTSI PWRLIVLWII
110 120 130 140 150
NIPFLIGMLG MIGGSHNLML PPIWQFALAS IVQLWLAIPF YRGAIGSIRG
160 170 180 190 200
GLTNMDVLVS TGTLTIYLYS AFMLFYHANH AMGHVYFEAS VMVIGFVSLG
210 220 230 240 250
KFLEDRTKKH SLNSLSMLLQ LTPKKVTVLR NEKWIEIALD QVNIGEIIRA
260 270 280 290 300
NQGERIAADG VIESGNGWCD ESHLTGESRP EEKQKGGKVL AGAMVTEGSI
310 320 330 340 350
IYRANQLGSQ TLLGDMMNAL SDAQGSKAPI ARFADKVTSV FVPVVLVISL
360 370 380 390 400
VTFALTYILT NDSVSSLIHA VSVLVIACPC ALGLATPAAI MVGLGKAVNA
410 420 430 440 450
GVWFKDAAAM EETAHVDTVV LDKTGTLTKG ELEISALWQP QSAVYSEDDL
460 470 480 490 500
YRFAAAVERQ ANHPIAKAIV QAAEXKMLEI PTALFSKMEV GQGIQAELEQ
510 520 530 540 550
VGTIKVGKPD YCGLILPKNL EDIWQIASIV AVSINDEPIG AFALTDTLKN
560 570 580 590 600
DSLHAIQRLQ QQNIDVVIMS GDQQSVVDYI AKQLGIKKAF GKLTPRDKAE
610 620 630 640 650
QIQKLKDLGH IVAMVGDGIN DAPALASANV SFAMKSSSDI AEQTASATLM
660 670 680 690 700
QHSVNQLVDA LFIARATLKN IKQNLFFALI YNILGIPLAA FGFLSPIIAG
710 720
AAMALSSISV LMNALRLKKV RF
Length:722
Mass (Da):78,072
Last modified:February 1, 1997 - v1
Checksum:iE4FF0BA5642EDCDD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC21955.1.
RefSeqiNP_438457.1. NC_000907.1.
WP_010868972.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC21955; AAC21955; HI_0290.
GeneIDi949726.
KEGGihin:HI0290.
PATRICifig|71421.8.peg.306.

Similar proteinsi

Entry informationi

Entry nameiY290_HAEIN
AccessioniPrimary (citable) accession number: P77868
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 22, 2017
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families