Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Beta-1,4-mannanase

Gene

manA

Organism
Caldicellulosiruptor saccharolyticus (Caldocellum saccharolyticum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi45Calcium; via carbonyl oxygenCombined sources1
Metal bindingi47CalciumCombined sources1
Metal bindingi79CalciumCombined sources1
Metal bindingi81Calcium; via carbonyl oxygenCombined sources1
Binding sitei141Beta-D-mannoseCombined sources1
Binding sitei196Beta-D-mannoseCombined sources1
Metal bindingi211CalciumCombined sources1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Keywords - Ligandi

CalciumCombined sources, Metal-bindingCombined sources

Protein family/group databases

CAZyiCBM27. Carbohydrate-Binding Module Family 27.
CBM35. Carbohydrate-Binding Module Family 35.
GH26. Glycoside Hydrolase Family 26.

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-1,4-mannanaseImported (EC:3.2.1.78Imported)
Gene namesi
Name:manAImported
OrganismiCaldicellulosiruptor saccharolyticus (Caldocellum saccharolyticum)Imported
Taxonomic identifieri44001 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisCaldicellulosiruptor

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1PMHX-ray1.06X36-220[»]
1PMJX-ray1.55X36-220[»]
ProteinModelPortaliP77847.
SMRiP77847.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP77847.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini450 – 574CBM6 (carbohydrate binding type-6)InterPro annotationAdd BLAST125
Domaini597 – 900GH26 (glycosyl hydrolase family 26)InterPro annotationAdd BLAST304

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni95 – 97Beta-D-mannose bindingCombined sources3
Regioni145 – 148Beta-D-mannose bindingCombined sources4

Family and domain databases

Gene3Di2.60.120.260. 3 hits.
3.20.20.80. 1 hit.
InterProiIPR015295. Carb-bd_module_27.
IPR005084. CMB_fam6.
IPR008979. Galactose-bd-like.
IPR022790. GH26_dom.
IPR000805. Glyco_hydro_26.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR40079. PTHR40079. 1 hit.
PfamiPF09212. CBM27. 2 hits.
PF03422. CBM_6. 1 hit.
PF02156. Glyco_hydro_26. 1 hit.
[Graphical view]
PRINTSiPR00739. GLHYDRLASE26.
SUPFAMiSSF49785. SSF49785. 3 hits.
SSF51445. SSF51445. 1 hit.
PROSITEiPS51175. CBM6. 1 hit.
PS51764. GH26. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77847-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVCLDMWRN WRVLFVLVTI IFLFSLIPTG IFGAVESSVN PVVLDFEDGT
60 70 80 90 100
VMSFGEAWGD SLKCIKKVSV SQDLQRPGNK YALRLDVEFN PNNGWDQGDL
110 120 130 140 150
GTWFGGVVEG QFDFTGYKSV EFEMFIPYDE FSKSQGGFPY KVVINDGWKE
160 170 180 190 200
LGSEFNITAN AGKKVKINGK DYTVIHKAFA IPEDFRTKKR AQLVFQFAGQ
210 220 230 240 250
NSNYKGPIYL DNVRIRPEDA SNLSKEDYGE QAEEGVAVED FFTGVKLVYP
260 270 280 290 300
EQGKSFVYNF EIDTMGFYKY SGDGFNKKTK SLEYSQDLKR SGNNGALKVN
310 320 330 340 350
ASLAGTAFDE MNIAIKLTDK DDKKFDFSKY STLEYTLYIP NPDKISGKLM
360 370 380 390 400
VASAIDNPWQ IIKDFTAINY KDKNAIQKIN GKDYAVIKCS DNLYNVNTKA
410 420 430 440 450
NVLVLRIAGS YVKYTGPIYI DNVKLVAGKK VAPKVKTTSS IPNIKNYYRV
460 470 480 490 500
KIEAETAKDG WAYSIEKENA KYSGKGYILL FGNNMGNTLY DLKIPKTGYY
510 520 530 540 550
IFTISSSTLG MVNYGSVDIW IDGELKGAAK VPNVKGKFQE VVVMKKIYLT
560 570 580 590 600
QGEHTLSLQK SGGYTIAIDY FTIEELVLAN KNKISVDTKL VTPNPHPNAQ
610 620 630 640 650
KLMKYLASIY GEKILSGQQS SGDGKEIQMI FDVTKRYPAV RGFDFMDYSP
660 670 680 690 700
SRVEHGTKGT DVEEAIKWWK SGGIVAFCWH WNAPTGLIDQ PGKEWWRGFY
710 720 730 740 750
TEATTFDIKK AMDNPNSTEY KLILRDIDAI AEQLKRLQKE GVPVLFRPLH
760 770 780 790 800
EASGGWFWWG AKGPEPYIKL WKLMFDRLVN YHKLNNLIWV WNGQDAAWYP
810 820 830 840 850
GDNYVDIIGE DIYEEKAQYS PYADRFAKAL KYTNARKMIA LTECGTIPDP
860 870 880 890 900
AVLKQEGISW SWFSVWAGNF VMTGSKYNDE WNDNHMLRKI YNSDYVITKD
910
ELPDIKNIPL K
Length:911
Mass (Da):103,325
Last modified:February 1, 1997 - v1
Checksum:iAD4A7FF0C1C8DF0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39812 Genomic DNA. Translation: AAC44232.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39812 Genomic DNA. Translation: AAC44232.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1PMHX-ray1.06X36-220[»]
1PMJX-ray1.55X36-220[»]
ProteinModelPortaliP77847.
SMRiP77847.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiCBM27. Carbohydrate-Binding Module Family 27.
CBM35. Carbohydrate-Binding Module Family 35.
GH26. Glycoside Hydrolase Family 26.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP77847.

Family and domain databases

Gene3Di2.60.120.260. 3 hits.
3.20.20.80. 1 hit.
InterProiIPR015295. Carb-bd_module_27.
IPR005084. CMB_fam6.
IPR008979. Galactose-bd-like.
IPR022790. GH26_dom.
IPR000805. Glyco_hydro_26.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR40079. PTHR40079. 1 hit.
PfamiPF09212. CBM27. 2 hits.
PF03422. CBM_6. 1 hit.
PF02156. Glyco_hydro_26. 1 hit.
[Graphical view]
PRINTSiPR00739. GLHYDRLASE26.
SUPFAMiSSF49785. SSF49785. 3 hits.
SSF51445. SSF51445. 1 hit.
PROSITEiPS51175. CBM6. 1 hit.
PS51764. GH26. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP77847_CALSA
AccessioniPrimary (citable) accession number: P77847
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.