Skip Header

 
Contribute Send feedback

Reviewed, UniProtKB/Swiss-Prot P77845 (ACKA_CORGL)

Last modified July 22, 2008. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase
Gene names
Name: ackA
Synonyms: ack
Ordered Locus Names: Cgl2752, cg3047
OrganismCorynebacterium glutamicum (Brevibacterium flavum) [Complete proteome] [HAMAP]
Taxonomic identifier1718 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Involved in the activation of acetate to acetyl CoA and the secretion of acetate By similarity.

Catalytic activity

ATP + acetate = ADP + acetyl phosphate.

ATP + propanoate = ADP + propanoyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords

   Cellular componentCytoplasm
   Molecular functionKinase
Transferase
   Technical termComplete proteome

Gene Ontology (GO)

   Biological processphosphorylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: HAMAP

   Molecular functionacetate kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical view

Molecule processing

Chain1 – 397397Acetate kinase

Sequences

Sequence LengthMass (Da)Tools
P77845-1 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 248FF97A3C52B0E4

FASTA39743,092
        10         20         30         40         50         60 
MALALVLNSG SSSIKFQLVN PENSAIDEPY VSGLVEQIGE PNGRIVLKIE GEKYTLETPI 

        70         80         90        100        110        120 
ADHSEGLNLA FDLMDQHNCG PSQLEITAVG HRVVHGGILF SAPELITDEI VEMIRDLIPL 

       130        140        150        160        170        180 
APLHNPANVD GIDVARKILP DVPHVAVFDT GFFHSLPPAA ALYAINKDVA AEHGIRRYGF 

       190        200        210        220        230        240 
HGTSHEFVSK RVVEILEKPT EDINTITFHL GNGASMAAVQ GGRAVDTSMG MTPLAGLVMG 

       250        260        270        280        290        300 
TRSGDIDPGI VFHLSRTAGM SIDEIDNLLN KKSGVKGLSG VNDFRELREM IDNNDQDAWS 

       310        320        330        340        350        360 
AYNIYIHQLR RYLGSYMVAL GRVDTIVFTA GVGENAQFVR EDALAGLEMY GIEIDPERNA 

       370        380        390 
LPNDGPRLIS TDASKVKVFV IPTNEELAIA RYAVKFA 

« Hide

References

« Hide 'large scale' references
[1]"Cloning, sequence analysis, expression and inactivation of the Corynebacterium glutamicum pta-ack operon encoding phosphotransacetylase and acetate kinase."
Reinscheid D.J., Schnicke S., Rittmann D., Zahnow U., Sahm H., Eikmanns B.J.
Microbiology 145:503-513(1999) [PubMed: 10075432] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[2]"Complete genomic sequence of Corynebacterium glutamicum ATCC 13032."
Nakagawa S.
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[3]"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins."
Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. expand/collapse author list , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.
J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases

X89084 Genomic DNA. Translation: CAA61456.1.
BA000036 Genomic DNA. Translation: BAC00146.1.
BX927156 Genomic DNA. Translation: CAF20774.1.
RefSeqNP_601947.1.
YP_226990.1.

3D structure databases

HSSPHSSP built from PDB template 1G99 based on UniProtKB P38502.
ModBaseSearch...

2-D gel databases

World-2DPAGE0001:P77845.

Genome annotation databases

GeneID1020697.
3344522.
GenomeReviewsGene locus cg3047 in contig BX927147_GR.
Gene locus Cgl2752 in contig BA000036_GR.
KEGGcgb:cg3047.
cgl:NCgl2656.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP77845.

Enzyme and pathway databases

BioCycCGLU196627-1:CG3047-MON.

Family and domain databases

HAMAPMF_00020.
[Tree]
InterProIPR000890. Acetate_kin.
IPR004372. AckA.
[Graphical view]
PANTHERPTHR21060. Acetate_kin. 1 hit.
PTHR21060:SF11. AckA. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. ackA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProDomP77845.
[Graphical view] [Entries sharing at least one domain]
BLOCKSSearch...

Other Resources

ProtoNetSearch...

Entry information

Entry nameACKA_CORGL
AccessionPrimary (citable) accession number: P77845
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: July 22, 2008
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Recent format changes

Overview of recent format changes

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents