P77844 (PTAS_CORGL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase
EC=2.3.1.8

Alternative name(s):
Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	Cgl2753, cg3048

Organism

Corynebacterium glutamicum (Brevibacterium flavum)

Taxonomic identifier

1718 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	329 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.
Sequence caution	The sequence CAF20775.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 329	329	Phosphate acetyltransferase		PRO_0000179128

Sequences

	Sequence		Length	Mass (Da)
	P77844 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: EE6E8C6F95432E06	FASTA	329	35,238
	10 20 30 40 50 60 MSAELFENWL LKRARAEHSH IVLPEGDDDR ILMAAHQLLD QDICDITILG DPVKIKERAT 70 80 90 100 110 120 ELGLHLNTAY LVNPLTDPRL EEFAEQFAEL RKSKSVTIDE AREIMKDISY FGTMMVHNGD 130 140 150 160 170 180 ADGMVSGAAN TTAHTIKPSF QIIKTVPEAS VVSSIFLMVL RGRLWAFGDC AVNPNPTAEQ 190 200 210 220 230 240 LGEIAVVSAK TAAQFGIDPR VAILSYSTGN SGGGSDVDRA IDALAEARRL NPELCVDGPL 250 260 270 280 290 300 QFDAAVDPGV ARKKMPDSDV AGQANVFIFP DLEAGNIGYK TAQRTGHALA VGPILQGLNK 310 320 PVNDLSRGAT VPDIVNTVAI TAIQAGGRS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning, sequence analysis, expression and inactivation of the Corynebacterium glutamicum pta-ack operon encoding phosphotransacetylase and acetate kinase." Reinscheid D.J., Schnicke S., Rittmann D., Zahnow U., Sahm H., Eikmanns B.J. Microbiology 145:503-513(1999) [PubMed: 10075432] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[2]	"Complete genomic sequence of Corynebacterium glutamicum ATCC 13032." Nakagawa S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[3]	"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins." Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A. J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X89084 Genomic DNA. Translation: CAA61455.1. BA000036 Genomic DNA. Translation: BAC00147.1. BX927156 Genomic DNA. Translation: CAF20775.1. Different initiation.
RefSeq	NP_601948.1. NC_003450.3. YP_226991.1. NC_006958.1.
3D structure databases
ProteinModelPortal	P77844.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1020698. 3344523.
GenomeReviews	Gene locus Cgl2753 in contig BA000036_GR. Gene locus cg3048 in contig BX927147_GR.
KEGG	cgb:cg3048. cgl:NCgl2657.
PATRIC	21497544. VBICorGlu203724_2684.
Phylogenomic databases
HOGENOM	HBG576804.
OMA	GCSTEDV.
PhylomeDB	P77844.
ProtClustDB	PRK09653.
Enzyme and pathway databases
BioCyc	CGLU196627:CG3048-MONOMER.
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K13788.
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTAS_CORGL

Accession

Primary (citable) accession number: P77844

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program