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P77835 (DEOD_GEOSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine nucleoside phosphorylase DeoD-type

Short name=PNP
EC=2.4.2.1
Alternative name(s):
Purine nucleoside phosphorylase II
Short name=PU-NPase II
Gene names
Name:deoD
Synonyms:punB
OrganismGeobacillus stearothermophilus (Bacillus stearothermophilus)
Taxonomic identifier1422 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length234 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Cleavage of adenosine and its derivatives. HAMAP-Rule MF_01627

Catalytic activity

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_01627

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
   Molecular functionGlycosyltransferase
Transferase
Gene Ontology (GO)
   Biological_processpurine nucleoside metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionpurine-nucleoside phosphorylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 234234Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627
PRO_0000063120

Sequences

Sequence LengthMass (Da)Tools
P77835 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 068CCF47EAA7DA09

FASTA23425,776
        10         20         30         40         50         60 
MSVHIGAKEH EIADKILLPG DPLRAKYIAE TFLEGATCYN QVRGMLGFTG TYKGHRISVQ 

        70         80         90        100        110        120 
GTGMGVPSIS IYITELMQSY NVQTLIRVGT CGAIQKDVKV RDVILAMTSS TDSQMNRMTF 

       130        140        150        160        170        180 
GGIDYAPTAN FDLLKTAYEI GKEKGLQLKV GSVFTADMFY NENAQFEKLA RYGVLAVEME 

       190        200        210        220        230 
TTALYTLAAK FGRKALSVLT VSDHILTGEE TTAEERQTTF NEMIEVALET AIRQ 

« Hide

References

[1]"Cloning of purine nucleoside phosphorylase II gene from Bacillus stearothermophilus TH 6-2 and characterization of its gene product."
Hamamoto T., Noguchi T., Midorikawa Y.
Biosci. Biotechnol. Biochem. 61:276-280(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
Strain: TH 6-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D87960 Genomic DNA. Translation: BAA13510.1.
PIRJT0874. JC5563.

3D structure databases

ProteinModelPortalP77835.
SMRP77835. Positions 1-233.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.50.1580. 1 hit.
HAMAPMF_01627. Pur_nucleosid_phosp.
InterProIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERPTHR21234. PTHR21234. 1 hit.
PfamPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMSSF53167. SSF53167. 1 hit.
TIGRFAMsTIGR00107. deoD. 1 hit.
PROSITEPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEOD_GEOSE
AccessionPrimary (citable) accession number: P77835
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families