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P77835

- DEOD_GEOSE

UniProt

P77835 - DEOD_GEOSE

Protein

Purine nucleoside phosphorylase DeoD-type

Gene

deoD

Organism
Geobacillus stearothermophilus (Bacillus stearothermophilus)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    • Comment

    Functioni

    Cleavage of adenosine and its derivatives.

    Catalytic activityi

    Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.
    Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.

    GO - Molecular functioni

    1. purine-nucleoside phosphorylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. purine nucleoside metabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Purine nucleoside phosphorylase DeoD-type (EC:2.4.2.1)
    Short name:
    PNP
    Alternative name(s):
    Purine nucleoside phosphorylase II
    Short name:
    PU-NPase II
    Gene namesi
    Name:deoD
    Synonyms:punB
    OrganismiGeobacillus stearothermophilus (Bacillus stearothermophilus)
    Taxonomic identifieri1422 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 234234Purine nucleoside phosphorylase DeoD-typePRO_0000063120Add
    BLAST

    Interactioni

    Subunit structurei

    Homohexamer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP77835.
    SMRiP77835. Positions 1-233.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PNP/UDP phosphorylase family.Curated

    Family and domain databases

    Gene3Di3.40.50.1580. 1 hit.
    HAMAPiMF_01627. Pur_nucleosid_phosp.
    InterProiIPR004402. DeoD-type.
    IPR018017. Nucleoside_phosphorylase.
    IPR018016. Nucleoside_phosphorylase_CS.
    IPR000845. Nucleoside_phosphorylase_d.
    [Graphical view]
    PANTHERiPTHR21234. PTHR21234. 1 hit.
    PfamiPF01048. PNP_UDP_1. 1 hit.
    [Graphical view]
    SUPFAMiSSF53167. SSF53167. 1 hit.
    TIGRFAMsiTIGR00107. deoD. 1 hit.
    PROSITEiPS01232. PNP_UDP_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P77835-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSVHIGAKEH EIADKILLPG DPLRAKYIAE TFLEGATCYN QVRGMLGFTG    50
    TYKGHRISVQ GTGMGVPSIS IYITELMQSY NVQTLIRVGT CGAIQKDVKV 100
    RDVILAMTSS TDSQMNRMTF GGIDYAPTAN FDLLKTAYEI GKEKGLQLKV 150
    GSVFTADMFY NENAQFEKLA RYGVLAVEME TTALYTLAAK FGRKALSVLT 200
    VSDHILTGEE TTAEERQTTF NEMIEVALET AIRQ 234
    Length:234
    Mass (Da):25,776
    Last modified:February 1, 1997 - v1
    Checksum:i068CCF47EAA7DA09
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D87960 Genomic DNA. Translation: BAA13510.1.
    PIRiJC5563. JT0874.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D87960 Genomic DNA. Translation: BAA13510.1 .
    PIRi JC5563. JT0874.

    3D structure databases

    ProteinModelPortali P77835.
    SMRi P77835. Positions 1-233.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.50.1580. 1 hit.
    HAMAPi MF_01627. Pur_nucleosid_phosp.
    InterProi IPR004402. DeoD-type.
    IPR018017. Nucleoside_phosphorylase.
    IPR018016. Nucleoside_phosphorylase_CS.
    IPR000845. Nucleoside_phosphorylase_d.
    [Graphical view ]
    PANTHERi PTHR21234. PTHR21234. 1 hit.
    Pfami PF01048. PNP_UDP_1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53167. SSF53167. 1 hit.
    TIGRFAMsi TIGR00107. deoD. 1 hit.
    PROSITEi PS01232. PNP_UDP_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of purine nucleoside phosphorylase II gene from Bacillus stearothermophilus TH 6-2 and characterization of its gene product."
      Hamamoto T., Noguchi T., Midorikawa Y.
      Biosci. Biotechnol. Biochem. 61:276-280(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
      Strain: TH 6-2.

    Entry informationi

    Entry nameiDEOD_GEOSE
    AccessioniPrimary (citable) accession number: P77835
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3