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Protein

Xylose isomerase

Gene

xylA

Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.

Cofactori

Mg2+By similarityNote: Binds 2 magnesium ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei99By similarity1
Active sitei102By similarity1
Metal bindingi230Magnesium 1By similarity1
Metal bindingi266Magnesium 1By similarity1
Metal bindingi266Magnesium 2By similarity1
Metal bindingi269Magnesium 2By similarity1
Metal bindingi294Magnesium 1By similarity1
Metal bindingi305Magnesium 2By similarity1
Metal bindingi307Magnesium 2By similarity1
Metal bindingi337Magnesium 1By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciBLIC279010:G1G12-4066-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomerase (EC:5.3.1.5)
Gene namesi
Name:xylA
Ordered Locus Names:BLi04048, BL03867
OrganismiBacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Taxonomic identifieri279010 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000606 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001957631 – 448Xylose isomeraseAdd BLAST448

Interactioni

Subunit structurei

Homotetramer.By similarity

Protein-protein interaction databases

STRINGi279010.BLi04048

Structurei

3D structure databases

ProteinModelPortaliP77832
SMRiP77832
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.Curated

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

P77832-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFRNIGMIE YEGADSENPY AFKYYNPDEF VGGKTMKEHL RFAVAYWHTF
60 70 80 90 100
DADGKDPFGD GTMFRAWNRL THPLDKAKAR AEAAFEFFEK LGVPYFCFHD
110 120 130 140 150
VDIVDEGATL RETFTYLDQM SSFLKEMMET SHVQLLWNTA NMFTHPRYVH
160 170 180 190 200
GAATSCNADV YAYAAAKVKK GLDIAKELGA ENYVFWGGRE GYETLLNTDM
210 220 230 240 250
KLELENLSSF YRMAVEYARE IGFDGQFLIE PKPKEPTKHQ YDFDAATTIA
260 270 280 290 300
FLETYGLKDH FKLNLEANHA TLAGHTFEHE LRVAALHDML GSIDANQGDL
310 320 330 340 350
LLGWDTDEFP TDLYSAVLAM YEILKAGGFK TGGINFDAKV RRPSFADEDL
360 370 380 390 400
FHAHIAGMDT YAVGLKVASR LLEDKALDQV IEERYESYTK GIGLEIKEGR
410 420 430 440
TDLKKLAAYA LENDHIENQS GRQERLKATV NRYLLNALRE APAGKETH
Length:448
Mass (Da):50,905
Last modified:February 1, 1997 - v1
Checksum:iF5769B6C12F452C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z80222 Genomic DNA Translation: CAB02314.1
X57601 Genomic DNA Translation: CAA40827.1
AE017333 Genomic DNA Translation: AAU42861.1
CP000002 Genomic DNA Translation: AAU25489.1
RefSeqiWP_011198415.1, NC_006322.1

Genome annotation databases

EnsemblBacteriaiAAU25489; AAU25489; BL03867
AAU42861; AAU42861; BLi04048
GeneIDi3030684
KEGGibld:BLi04048
bli:BL03867
PATRICifig|279010.13.peg.4125

Similar proteinsi

Entry informationi

Entry nameiXYLA_BACLD
AccessioniPrimary (citable) accession number: P77832
Secondary accession number(s): Q65DK3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: February 1, 1997
Last modified: April 25, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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