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Protein

RNA polymerase sigma factor

Gene

rpoD

Organism
Borrelia garinii
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
  3. sigma factor activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA-templated transcription, initiation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Sigma factorUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factorUniRule annotation
Gene namesi
Name:rpoDImported
OrganismiBorrelia gariniiImported
Taxonomic identifieri29519 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group

Structurei

3D structure databases

ProteinModelPortaliP77826.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sigma-70 factor family.UniRule annotation

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
HAMAPiMF_00963. Sigma70_RpoD_SigA.
InterProiIPR014284. RNA_pol_sigma-70_dom.
IPR000943. RNA_pol_sigma70.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR012760. RNA_pol_sigma_RpoD_C.
IPR028630. Sigma70_RpoD.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
[Graphical view]
PRINTSiPR00046. SIGMA70FCT.
SUPFAMiSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02393. RpoD_Cterm. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEiPS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P77826-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QMDSGESIIE NILKNEGLVI ENYYNLINTI YSRMEREEFF KREKDKDKES
60 70 80 90 100
NPDYYNKKKR IASFYKIPLK PIQDRLISYV DNKHRVYELG GDIFEKNLKS
110 120 130 140 150
ERLALKELLR NVPLYQDELR IFSDDYIDSA NKIKDLQRQQ RIILSRLKIE
160 170 180 190 200
KIRDLRVLGR DLTIAEKRIE IEKSLKLKED AIKEQITEAQ LAQKELERIE
210 220 230 240 250
MYYEYPMDKI ISMSEEIAKG KQMMQHAKDQ LIKANLRLVV SIAKKYANRG
260 270 280 290 300
LHFFDLVQEG NIGLIKAVEK FEYKRGFKFS TYATWWIRQA ITRSISDQAR
310 320 330 340 350
TIRVPVHMIE QINRLNRETR YLVQVLGKDP TDEELSDRLG WELKKVKTVK
360 370 380 390 400
SVSREPVSLE TPIGEEEDSV LSDFIEDKAI KNPANHTSFV VLQDQIRSIL
410 420 430 440 450
GTLPEREQEV VKMRFGLEDG YSLTLEEVGL HFNVTRERIR QIESKALRRL
Length:450
Mass (Da):53,109
Last modified:February 1, 1997 - v1
Checksum:i116292CAB8984F1B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei450 – 4501Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U68012 Genomic DNA. Translation: AAC45105.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U68012 Genomic DNA. Translation: AAC45105.1.

3D structure databases

ProteinModelPortaliP77826.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
HAMAPiMF_00963. Sigma70_RpoD_SigA.
InterProiIPR014284. RNA_pol_sigma-70_dom.
IPR000943. RNA_pol_sigma70.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR012760. RNA_pol_sigma_RpoD_C.
IPR028630. Sigma70_RpoD.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
[Graphical view]
PRINTSiPR00046. SIGMA70FCT.
SUPFAMiSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02393. RpoD_Cterm. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEiPS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Pan M.
    Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K48Imported.
  2. "Sequence diversity of a gene encoding a putative primary sigma factor among Borrelia burgdorferi sensu lato strains."
    Pan M.-J., Tsai C.-P., Yeh J.C.
    FEMS Microbiol. Lett. 148:153-158(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K48Imported.

Entry informationi

Entry nameiP77826_BORGR
AccessioniPrimary (citable) accession number: P77826
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: March 4, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.