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Protein

Spheroplast protein Y

Gene

spy

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Could be involved in zinc resistance or another aspect of zinc metabolism.

GO - Biological processi

  1. chaperone-mediated protein folding Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G6939-MONOMER.
ECOL316407:JW1732-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Spheroplast protein Y
Gene namesi
Name:spy
Ordered Locus Names:b1743, JW1732
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318 Componenti: Chromosome UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13490. spy.

Subcellular locationi

GO - Cellular componenti

  1. outer membrane-bounded periplasmic space Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 23232 PublicationsAdd
BLAST
Chaini24 – 161138Spheroplast protein YPRO_0000022405Add
BLAST

Proteomic databases

PaxDbiP77754.
PRIDEiP77754.

Expressioni

Developmental stagei

Produced abundantly in spheroplasts.

Gene expression databases

GenevestigatoriP77754.

Interactioni

Protein-protein interaction databases

IntActiP77754. 2 interactions.
STRINGi511145.b1743.

Structurei

3D structure databases

ProteinModelPortaliP77754.
SMRiP77754. Positions 52-147.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To E.coli CpxP.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG3678.
HOGENOMiHOG000285733.
InParanoidiP77754.
OMAiKMYNLLT.
OrthoDBiEOG63Z790.
PhylomeDBiP77754.

Family and domain databases

InterProiIPR012899. LTXXQ.
[Graphical view]
PfamiPF07813. LTXXQ. 1 hit.
[Graphical view]
PIRSFiPIRSF034445. CpxP_Spy. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P77754-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKLTALFVA STLALGAANL AHAADTTTAA PADAKPMMHH KGKFGPHQDM
60 70 80 90 100
MFKDLNLTDA QKQQIREIMK GQRDQMKRPP LEERRAMHDI IASDTFDKVK
110 120 130 140 150
AEAQIAKMEE QRKANMLAHM ETQNKIYNIL TPEQKKQFNA NFEKRLTERP
160
AAKGKMPATA E
Length:161
Mass (Da):18,199
Last modified:February 1, 1997 - v1
Checksum:iB4733B967FC5F5BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y07714 Genomic DNA. Translation: CAA68986.1.
U00096 Genomic DNA. Translation: AAC74813.1.
AP009048 Genomic DNA. Translation: BAA15531.1.
PIRiG64933.
RefSeqiNP_416257.1. NC_000913.3.
YP_490004.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC74813; AAC74813; b1743.
BAA15531; BAA15531; BAA15531.
GeneIDi12933243.
946253.
KEGGiecj:Y75_p1718.
eco:b1743.
PATRICi32118795. VBIEscCol129921_1815.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y07714 Genomic DNA. Translation: CAA68986.1.
U00096 Genomic DNA. Translation: AAC74813.1.
AP009048 Genomic DNA. Translation: BAA15531.1.
PIRiG64933.
RefSeqiNP_416257.1. NC_000913.3.
YP_490004.1. NC_007779.1.

3D structure databases

ProteinModelPortaliP77754.
SMRiP77754. Positions 52-147.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP77754. 2 interactions.
STRINGi511145.b1743.

Proteomic databases

PaxDbiP77754.
PRIDEiP77754.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74813; AAC74813; b1743.
BAA15531; BAA15531; BAA15531.
GeneIDi12933243.
946253.
KEGGiecj:Y75_p1718.
eco:b1743.
PATRICi32118795. VBIEscCol129921_1815.

Organism-specific databases

EchoBASEiEB3263.
EcoGeneiEG13490. spy.

Phylogenomic databases

eggNOGiCOG3678.
HOGENOMiHOG000285733.
InParanoidiP77754.
OMAiKMYNLLT.
OrthoDBiEOG63Z790.
PhylomeDBiP77754.

Enzyme and pathway databases

BioCyciEcoCyc:G6939-MONOMER.
ECOL316407:JW1732-MONOMER.

Miscellaneous databases

PROiP77754.

Gene expression databases

GenevestigatoriP77754.

Family and domain databases

InterProiIPR012899. LTXXQ.
[Graphical view]
PfamiPF07813. LTXXQ. 1 hit.
[Graphical view]
PIRSFiPIRSF034445. CpxP_Spy. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A new periplasmic protein of Escherichia coli which is synthesized in spheroplasts but not in intact cells."
    Hagenmaier S., Stierhof Y.-D., Henning U.
    J. Bacteriol. 179:2073-2076(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 24-40.
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Identification of a novel transcription regulator from Proteus mirabilis, PMTR, revealed a possible role of YJAI protein in balancing zinc in Escherichia coli."
    Noll M., Petrukhin K., Lutsenko S.
    J. Biol. Chem. 273:21393-21401(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 24-38.

Entry informationi

Entry nameiSPY_ECOLI
AccessioniPrimary (citable) accession number: P77754
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: January 7, 2015
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.