Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Outer membrane protein N

Gene

ompN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Forms pores that allow passive diffusion of small molecules across the outer membrane (By similarity). Non-specific porin.By similarity

GO - Molecular functioni

  • porin activity Source: EcoCyc

GO - Biological processi

  • carbohydrate transmembrane transport Source: EcoCyc
  • ion transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Porin

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G6700-MONOMER.
ECOL316407:JW1371-MONOMER.

Protein family/group databases

TCDBi1.B.1.1.21. the general bacterial porin (gbp) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane protein N
Alternative name(s):
Porin OmpN
Gene namesi
Name:ompN
Synonyms:ynaG
Ordered Locus Names:b1377, JW1371
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13375. ompN.

Subcellular locationi

GO - Cellular componenti

  • cell outer membrane Source: UniProtKB-SubCell
  • membrane Source: EcoCyc
  • pore complex Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 21211 PublicationAdd
BLAST
Chaini22 – 377356Outer membrane protein NPRO_0000025250Add
BLAST

Proteomic databases

PaxDbiP77747.
PRIDEiP77747.

Interactioni

Subunit structurei

Homotrimer.

Protein-protein interaction databases

BioGridi4260172. 280 interactions.
DIPiDIP-10400N.
STRINGi511145.b1377.

Structurei

3D structure databases

ProteinModelPortaliP77747.
SMRiP77747. Positions 22-377.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Gram-negative porin family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4105FCK. Bacteria.
COG3203. LUCA.
HOGENOMiHOG000272406.
InParanoidiP77747.
KOiK14062.
OMAiNGRDIRH.
PhylomeDBiP77747.

Family and domain databases

Gene3Di2.40.160.10. 1 hit.
InterProiIPR023614. Porin_dom.
IPR001897. Porin_gammaproteobac.
IPR001702. Porin_Gram-ve.
[Graphical view]
PfamiPF00267. Porin_1. 1 hit.
[Graphical view]
PRINTSiPR00183. ECOLIPORIN.
PR00182. ECOLNEIPORIN.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P77747-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSKVLALLI PALLAAGAAH AAEVYNKDGN KLDLYGKVDG LHYFSDNSAK
60 70 80 90 100
DGDQSYARLG FKGETQINDQ LTGYGQWEYN IQANNTESSK NQSWTRLAFA
110 120 130 140 150
GLKFADYGSF DYGRNYGVMY DIEGWTDMLP EFGGDSYTNA DNFMTGRANG
160 170 180 190 200
VATYRNTDFF GLVNGLNFAV QYQGNNEGAS NGQEGTNNGR DVRHENGDGW
210 220 230 240 250
GLSTTYDLGM GFSAGAAYTS SDRTNDQVNH TAAGGDKADA WTAGLKYDAN
260 270 280 290 300
NIYLATMYSE TRNMTPFGDS DYAVANKTQN FEVTAQYQFD FGLRPAVSFL
310 320 330 340 350
MSKGRDLHAA GGADNPAGVD DKDLVKYADI GATYYFNKNM STYVDYKINL
360 370
LDEDDSFYAA NGISTDDIVA LGLVYQF
Length:377
Mass (Da):41,220
Last modified:February 1, 1997 - v1
Checksum:i4420D2CB9BC10F95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74459.1.
AP009048 Genomic DNA. Translation: BAA14981.1.
PIRiD64888.
RefSeqiNP_415895.1. NC_000913.3.
WP_000837921.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74459; AAC74459; b1377.
BAA14981; BAA14981; BAA14981.
GeneIDi946313.
KEGGiecj:JW1371.
eco:b1377.
PATRICi32118038. VBIEscCol129921_1439.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74459.1.
AP009048 Genomic DNA. Translation: BAA14981.1.
PIRiD64888.
RefSeqiNP_415895.1. NC_000913.3.
WP_000837921.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77747.
SMRiP77747. Positions 22-377.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260172. 280 interactions.
DIPiDIP-10400N.
STRINGi511145.b1377.

Protein family/group databases

TCDBi1.B.1.1.21. the general bacterial porin (gbp) family.

Proteomic databases

PaxDbiP77747.
PRIDEiP77747.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74459; AAC74459; b1377.
BAA14981; BAA14981; BAA14981.
GeneIDi946313.
KEGGiecj:JW1371.
eco:b1377.
PATRICi32118038. VBIEscCol129921_1439.

Organism-specific databases

EchoBASEiEB3157.
EcoGeneiEG13375. ompN.

Phylogenomic databases

eggNOGiENOG4105FCK. Bacteria.
COG3203. LUCA.
HOGENOMiHOG000272406.
InParanoidiP77747.
KOiK14062.
OMAiNGRDIRH.
PhylomeDBiP77747.

Enzyme and pathway databases

BioCyciEcoCyc:G6700-MONOMER.
ECOL316407:JW1371-MONOMER.

Miscellaneous databases

PROiP77747.

Family and domain databases

Gene3Di2.40.160.10. 1 hit.
InterProiIPR023614. Porin_dom.
IPR001897. Porin_gammaproteobac.
IPR001702. Porin_Gram-ve.
[Graphical view]
PfamiPF00267. Porin_1. 1 hit.
[Graphical view]
PRINTSiPR00183. ECOLIPORIN.
PR00182. ECOLNEIPORIN.
ProtoNetiSearch...

Entry informationi

Entry nameiOMPN_ECOLI
AccessioniPrimary (citable) accession number: P77747
Secondary accession number(s): P76854
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.