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Protein

HTH-type transcriptional regulator AbgR

Gene

abgR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Could be the regulator of the abg operon.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi22 – 4120H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6671-MONOMER.
ECOL316407:JW1333-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator AbgR
Gene namesi
Name:abgR
Ordered Locus Names:b1339, JW1333
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13353. abgR.

Pathology & Biotechi

Disruption phenotypei

Cells lacking this gene may lead to an altered expression of abgT.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302HTH-type transcriptional regulator AbgRPRO_0000105583Add
BLAST

Proteomic databases

PaxDbiP77744.

Interactioni

Protein-protein interaction databases

BioGridi4262879. 13 interactions.
IntActiP77744. 2 interactions.
STRINGi511145.b1339.

Structurei

3D structure databases

ProteinModelPortaliP77744.
SMRiP77744. Positions 5-290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 6258HTH lysR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4106KR7. Bacteria.
ENOG410XQ2C. LUCA.
HOGENOMiHOG000233526.
InParanoidiP77744.
KOiK14057.
OMAiKATYYLI.
PhylomeDBiP77744.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77744-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFQVKIHQI RAFVEVARQG SIRGASRMLN MSQPALSKSI QELEEGLAAQ
60 70 80 90 100
LFFRRSKGVT LTDAGESFYQ HASLILEELR AAQEDIRQRQ GQLAGQINIG
110 120 130 140 150
MGASISRSLM PAVISRFHQQ HPQVKVRIME GQLVSMINEL RQGELDFTIN
160 170 180 190 200
TYYQGPYDHE FTFEKLLEKQ FAIFCRPGHP AIGARSIKQL LDYSWTMPTP
210 220 230 240 250
HGSYYKQLSE LLDDQAQTPQ VGVVCETFSA CISLVAKSDF LSKLPEEMGC
260 270 280 290 300
DPLHGQGLVM LPVSEILPKA AYYLIQRRDS RQTPLTASLI TQFRRECGYL

QS
Length:302
Mass (Da):34,058
Last modified:February 1, 1997 - v1
Checksum:i57C83FA6DF8ABA66
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74421.1.
AP009048 Genomic DNA. Translation: BAA14941.1.
PIRiF64883.
RefSeqiNP_415855.1. NC_000913.3.
WP_000885458.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74421; AAC74421; b1339.
BAA14941; BAA14941; BAA14941.
GeneIDi945831.
KEGGiecj:JW1333.
eco:b1339.
PATRICi32117956. VBIEscCol129921_1398.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74421.1.
AP009048 Genomic DNA. Translation: BAA14941.1.
PIRiF64883.
RefSeqiNP_415855.1. NC_000913.3.
WP_000885458.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77744.
SMRiP77744. Positions 5-290.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262879. 13 interactions.
IntActiP77744. 2 interactions.
STRINGi511145.b1339.

Proteomic databases

PaxDbiP77744.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74421; AAC74421; b1339.
BAA14941; BAA14941; BAA14941.
GeneIDi945831.
KEGGiecj:JW1333.
eco:b1339.
PATRICi32117956. VBIEscCol129921_1398.

Organism-specific databases

EchoBASEiEB3136.
EcoGeneiEG13353. abgR.

Phylogenomic databases

eggNOGiENOG4106KR7. Bacteria.
ENOG410XQ2C. LUCA.
HOGENOMiHOG000233526.
InParanoidiP77744.
KOiK14057.
OMAiKATYYLI.
PhylomeDBiP77744.

Enzyme and pathway databases

BioCyciEcoCyc:G6671-MONOMER.
ECOL316407:JW1333-MONOMER.

Miscellaneous databases

PROiP77744.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiABGR_ECOLI
AccessioniPrimary (citable) accession number: P77744
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.