Reviewed, UniProtKB/Swiss-Prot P77744 (ABGR_ECOLI)

Names and origin

Protein names

Recommended name:
    HTH-type transcriptional regulator abgR

Gene names

Name:	abgR
Ordered Locus Names:	b1339, JW1333

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Could be the regulator of the abg operon.
Sequence similarities	Contains 1 HTH lysR-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro transcription Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	HTH-type transcriptional regulator abgR		PRO_0000105583
Regions
	Domain	5 – 62	58	HTH lysR-type
	DNA binding	22 – 41	20	H-T-H motif Potential

Sequences

	Sequence		Length	Mass (Da)
	P77744-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 57C83FA6DF8ABA66	FASTA	302	34,058
	10 20 30 40 50 60 MAFQVKIHQI RAFVEVARQG SIRGASRMLN MSQPALSKSI QELEEGLAAQ LFFRRSKGVT 70 80 90 100 110 120 LTDAGESFYQ HASLILEELR AAQEDIRQRQ GQLAGQINIG MGASISRSLM PAVISRFHQQ 130 140 150 160 170 180 HPQVKVRIME GQLVSMINEL RQGELDFTIN TYYQGPYDHE FTFEKLLEKQ FAIFCRPGHP 190 200 210 220 230 240 AIGARSIKQL LDYSWTMPTP HGSYYKQLSE LLDDQAQTPQ VGVVCETFSA CISLVAKSDF 250 260 270 280 290 300 LSKLPEEMGC DPLHGQGLVM LPVSEILPKA AYYLIQRRDS RQTPLTASLI TQFRRECGYL QS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:363-377(1996) [PubMed: 9097039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Characterization of mutations that allow p-aminobenzoyl-glutamate utilization by Escherichia coli." Hussein M.J., Green J.M., Nichols B.P. J. Bacteriol. 180:6260-6268(1998) [PubMed: 9829935] [Abstract] Cited for: CHARACTERIZATION. Strain: BN101.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00096 Genomic DNA. Translation: AAC74421.1. AP009048 Genomic DNA. Translation: BAA14941.1.
PIR	F64883.
RefSeq	AP_001967.1. NP_415855.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	P77744.
Genome annotation databases
GeneID	945831.
GenomeReviews	Gene locus JW1333 in contig AP009048_GR. Gene locus b1339 in contig U00096_GR.
KEGG	ecj:JW1333. eco:b1339.
Organism-specific databases
EchoBASE	EB3136.
EcoGene	EG13353. abgR.
CMR	Search...
Phylogenomic databases
HOGENOM	P77744.
OMA	IVARKEH
Enzyme and pathway databases
BioCyc	EcoCyc:G6671-MON. ECOL168927:B1339-MON.
Gene expression databases
Genevestigator	P77744.
Family and domain databases
InterPro	IPR000847. HTH_LysR. IPR005119. LysR_subst_bd. IPR011991. Wing_hlx_DNA_bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
Pfam	PF00126. HTH_1. 1 hit. PF03466. LysR_substrate. 1 hit. [Graphical view]
PRINTS	PR00039. HTHLYSR.
PROSITE	PS50931. HTH_LYSR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABGR_ECOLI

Accession

Primary (citable) accession number: P77744

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	February 1, 1997
Last modified:	November 24, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)