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Protein

Uncharacterized oxidoreductase YajO

Gene

yajO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei61Proton donorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi212 – 222NADPBy similarityAdd BLAST11

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciEcoCyc:G6236-MONOMER.
ECOL316407:JW0409-MONOMER.
MetaCyc:G6236-MONOMER.

Protein family/group databases

TCDBi8.A.5.1.6. the voltage-gated k(+) channel -subunit (kv) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YajO (EC:1.-.-.-)
Gene namesi
Name:yajO
Ordered Locus Names:b0419, JW0409
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13611. yajO.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000703921 – 324Uncharacterized oxidoreductase YajOAdd BLAST324

Proteomic databases

PaxDbiP77735.
PRIDEiP77735.

Interactioni

Protein-protein interaction databases

BioGridi4259835. 105 interactors.
DIPiDIP-11291N.
IntActiP77735. 6 interactors.
STRINGi511145.b0419.

Structurei

3D structure databases

ProteinModelPortaliP77735.
SMRiP77735.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CPC. Bacteria.
COG0667. LUCA.
HOGENOMiHOG000250270.
InParanoidiP77735.
OMAiSDWREWV.
PhylomeDBiP77735.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 2 hits.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.

Sequencei

Sequence statusi: Complete.

P77735-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQYNPLGKTD LRVSRLCLGC MTFGEPDRGN HAWTLPEESS RPIIKRALEG
60 70 80 90 100
GINFFDTANS YSDGSSEEIV GRALRDFARR EDVVVATKVF HRVGDLPEGL
110 120 130 140 150
SRAQILRSID DSLRRLGMDY VDILQIHRWD YNTPIEETLE ALNDVVKAGK
160 170 180 190 200
ARYIGASSMH ASQFAQALEL QKQHGWAQFV SMQDHYNLIY REEEREMLPL
210 220 230 240 250
CYQEGVAVIP WSPLARGRLT RPWGETTARL VSDEVGKNLY KESDENDAQI
260 270 280 290 300
AERLTGVSEE LGATRAQVAL AWLLSKPGIA APIIGTSREE QLDELLNAVD
310 320
ITLKPEQIAE LETPYKPHPV VGFK
Length:324
Mass (Da):36,420
Last modified:December 15, 1998 - v2
Checksum:i0B69E09F2BEDF9B1
GO

Sequence cautioni

The sequence AAB40175 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82664 Genomic DNA. Translation: AAB40175.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73522.2.
AP009048 Genomic DNA. Translation: BAE76199.1.
PIRiC64771.
RefSeqiNP_414953.2. NC_000913.3.
WP_001199800.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73522; AAC73522; b0419.
BAE76199; BAE76199; BAE76199.
GeneIDi946903.
KEGGiecj:JW0409.
eco:b0419.
PATRICi32115987. VBIEscCol129921_0435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82664 Genomic DNA. Translation: AAB40175.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73522.2.
AP009048 Genomic DNA. Translation: BAE76199.1.
PIRiC64771.
RefSeqiNP_414953.2. NC_000913.3.
WP_001199800.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77735.
SMRiP77735.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259835. 105 interactors.
DIPiDIP-11291N.
IntActiP77735. 6 interactors.
STRINGi511145.b0419.

Protein family/group databases

TCDBi8.A.5.1.6. the voltage-gated k(+) channel -subunit (kv) family.

Proteomic databases

PaxDbiP77735.
PRIDEiP77735.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73522; AAC73522; b0419.
BAE76199; BAE76199; BAE76199.
GeneIDi946903.
KEGGiecj:JW0409.
eco:b0419.
PATRICi32115987. VBIEscCol129921_0435.

Organism-specific databases

EchoBASEiEB3377.
EcoGeneiEG13611. yajO.

Phylogenomic databases

eggNOGiENOG4105CPC. Bacteria.
COG0667. LUCA.
HOGENOMiHOG000250270.
InParanoidiP77735.
OMAiSDWREWV.
PhylomeDBiP77735.

Enzyme and pathway databases

BioCyciEcoCyc:G6236-MONOMER.
ECOL316407:JW0409-MONOMER.
MetaCyc:G6236-MONOMER.

Miscellaneous databases

PROiP77735.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 2 hits.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYAJO_ECOLI
AccessioniPrimary (citable) accession number: P77735
Secondary accession number(s): Q2MC07
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 15, 1998
Last modified: November 2, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.