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Protein

Uncharacterized HTH-type transcriptional regulator RhmR

Gene

rhmR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi28 – 47H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: GO_Central
  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7161-MONOMER.
ECOL316407:JW2242-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator RhmR
Gene namesi
Name:rhmR
Synonyms:yfaX
Ordered Locus Names:b2248, JW2242
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14086. rhmR.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002017701 – 260Uncharacterized HTH-type transcriptional regulator RhmRAdd BLAST260

Proteomic databases

PaxDbiP77732.
PRIDEiP77732.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
priCP238623EBI-549004,EBI-1117383

Protein-protein interaction databases

BioGridi4261223. 5 interactors.
DIPiDIP-11956N.
IntActiP77732. 4 interactors.
STRINGi511145.b2248.

Structurei

3D structure databases

ProteinModelPortaliP77732.
SMRiP77732.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 67HTH iclR-typePROSITE-ProRule annotationAdd BLAST61
Domaini82 – 251IclR-EDPROSITE-ProRule annotationAdd BLAST170

Sequence similaritiesi

Contains 1 HTH iclR-type DNA-binding domain.PROSITE-ProRule annotation
Contains 1 iclR-ED (iclR effector binding) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4107258. Bacteria.
COG1414. LUCA.
HOGENOMiHOG000107041.
InParanoidiP77732.
OMAiVWERATP.
PhylomeDBiP77732.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.30.450.40. 1 hit.
InterProiIPR029016. GAF_dom-like.
IPR014757. Tscrpt_reg_IclR_C.
IPR005471. Tscrpt_reg_IclR_N.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF09339. HTH_IclR. 1 hit.
PF01614. IclR. 1 hit.
[Graphical view]
SMARTiSM00346. HTH_ICLR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF55781. SSF55781. 1 hit.
PROSITEiPS51077. HTH_ICLR. 1 hit.
PS51078. ICLR_ED. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77732-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLESSKVPAL TRAIDILNLI ARIGPCSAAT IIDTLGIPKS TAYLLLNELR
60 70 80 90 100
RQRFLSLDHQ ENFCLWTRLV ELSGHALSKM DLRELARPRL TQLMDTTGLL
110 120 130 140 150
CHLGIIDNGS AYYILKVESS ATISVRSHEG KSLSLYRSGI GKCLLAWQPA
160 170 180 190 200
AVQQSIIEGL VWEQATPTTI THPQQLHEEL ARIRRQGWSY DNGEDYADVR
210 220 230 240 250
CVAAPVFNAN NELTAAISVV GTRLQINEEY RDYLAGKAIA CARDISRLLG
260
WKSPFDLQAS
Length:260
Mass (Da):28,904
Last modified:February 1, 1997 - v1
Checksum:i27016904BD41553C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75308.1.
AP009048 Genomic DNA. Translation: BAA16072.1.
PIRiF64995.
RefSeqiNP_416751.1. NC_000913.3.
WP_000894185.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75308; AAC75308; b2248.
BAA16072; BAA16072; BAA16072.
GeneIDi944752.
KEGGiecj:JW2242.
eco:b2248.
PATRICi32119859. VBIEscCol129921_2339.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75308.1.
AP009048 Genomic DNA. Translation: BAA16072.1.
PIRiF64995.
RefSeqiNP_416751.1. NC_000913.3.
WP_000894185.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77732.
SMRiP77732.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261223. 5 interactors.
DIPiDIP-11956N.
IntActiP77732. 4 interactors.
STRINGi511145.b2248.

Proteomic databases

PaxDbiP77732.
PRIDEiP77732.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75308; AAC75308; b2248.
BAA16072; BAA16072; BAA16072.
GeneIDi944752.
KEGGiecj:JW2242.
eco:b2248.
PATRICi32119859. VBIEscCol129921_2339.

Organism-specific databases

EchoBASEiEB3839.
EcoGeneiEG14086. rhmR.

Phylogenomic databases

eggNOGiENOG4107258. Bacteria.
COG1414. LUCA.
HOGENOMiHOG000107041.
InParanoidiP77732.
OMAiVWERATP.
PhylomeDBiP77732.

Enzyme and pathway databases

BioCyciEcoCyc:G7161-MONOMER.
ECOL316407:JW2242-MONOMER.

Miscellaneous databases

PROiP77732.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.30.450.40. 1 hit.
InterProiIPR029016. GAF_dom-like.
IPR014757. Tscrpt_reg_IclR_C.
IPR005471. Tscrpt_reg_IclR_N.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF09339. HTH_IclR. 1 hit.
PF01614. IclR. 1 hit.
[Graphical view]
SMARTiSM00346. HTH_ICLR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF55781. SSF55781. 1 hit.
PROSITEiPS51077. HTH_ICLR. 1 hit.
PS51078. ICLR_ED. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRHMR_ECOLI
AccessioniPrimary (citable) accession number: P77732
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Part of the rhmRDTA operon involved in L-rhamnonate utilization.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.