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Protein

Uncharacterized HTH-type transcriptional regulator RhmR

Gene

rhmR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Part of the rhmRDTA operon involved in L-rhamnonate utilization.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi28 – 47H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: GO_Central
  • transcription, DNA-templated Source: EcoCyc

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G7161-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator RhmR
Gene namesi
Name:rhmR
Synonyms:yfaX
Ordered Locus Names:b2248, JW2242
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14086 rhmR

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002017701 – 260Uncharacterized HTH-type transcriptional regulator RhmRAdd BLAST260

Proteomic databases

PaxDbiP77732
PRIDEiP77732

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
priCP238623EBI-549004,EBI-1117383

Protein-protein interaction databases

BioGridi4261223, 5 interactors
DIPiDIP-11956N
IntActiP77732, 4 interactors
STRINGi316385.ECDH10B_2408

Structurei

3D structure databases

ProteinModelPortaliP77732
SMRiP77732
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 67HTH iclR-typePROSITE-ProRule annotationAdd BLAST61
Domaini82 – 251IclR-EDPROSITE-ProRule annotationAdd BLAST170

Phylogenomic databases

eggNOGiENOG4107258 Bacteria
COG1414 LUCA
HOGENOMiHOG000107041
InParanoidiP77732
OMAiPKSSLYM
PhylomeDBiP77732

Family and domain databases

Gene3Di1.10.10.10, 1 hit
3.30.450.40, 1 hit
InterProiView protein in InterPro
IPR029016 GAF-like_dom_sf
IPR014757 Tscrpt_reg_IclR_C
IPR005471 Tscrpt_reg_IclR_N
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF09339 HTH_IclR, 1 hit
PF01614 IclR, 1 hit
SMARTiView protein in SMART
SM00346 HTH_ICLR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS51077 HTH_ICLR, 1 hit
PS51078 ICLR_ED, 1 hit

Sequencei

Sequence statusi: Complete.

P77732-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLESSKVPAL TRAIDILNLI ARIGPCSAAT IIDTLGIPKS TAYLLLNELR
60 70 80 90 100
RQRFLSLDHQ ENFCLWTRLV ELSGHALSKM DLRELARPRL TQLMDTTGLL
110 120 130 140 150
CHLGIIDNGS AYYILKVESS ATISVRSHEG KSLSLYRSGI GKCLLAWQPA
160 170 180 190 200
AVQQSIIEGL VWEQATPTTI THPQQLHEEL ARIRRQGWSY DNGEDYADVR
210 220 230 240 250
CVAAPVFNAN NELTAAISVV GTRLQINEEY RDYLAGKAIA CARDISRLLG
260
WKSPFDLQAS
Length:260
Mass (Da):28,904
Last modified:February 1, 1997 - v1
Checksum:i27016904BD41553C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75308.1
AP009048 Genomic DNA Translation: BAA16072.1
PIRiF64995
RefSeqiNP_416751.1, NC_000913.3
WP_000894185.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75308; AAC75308; b2248
BAA16072; BAA16072; BAA16072
GeneIDi944752
KEGGiecj:JW2242
eco:b2248
PATRICifig|511145.12.peg.2339

Similar proteinsi

Entry informationi

Entry nameiRHMR_ECOLI
AccessioniPrimary (citable) accession number: P77732
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health