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Protein

Inner membrane transport protein YajR

Gene

yajR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • transmembrane transport Source: EcoCyc
  • transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:B0427-MONOMER.
ECOL316407:JW5059-MONOMER.

Protein family/group databases

TCDBi2.A.1.2.60. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane transport protein YajR
Gene namesi
Name:yajR
Ordered Locus Names:b0427, JW5059
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13614. yajR.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 14PeriplasmicSequence analysisAdd BLAST14
Transmembranei15 – 35HelicalSequence analysisAdd BLAST21
Topological domaini36 – 47CytoplasmicSequence analysisAdd BLAST12
Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Topological domaini69 – 84PeriplasmicSequence analysisAdd BLAST16
Transmembranei85 – 105HelicalSequence analysisAdd BLAST21
Topological domaini106 – 137CytoplasmicSequence analysisAdd BLAST32
Transmembranei138 – 158HelicalSequence analysisAdd BLAST21
Topological domaini159 – 165PeriplasmicSequence analysis7
Transmembranei166 – 186HelicalSequence analysisAdd BLAST21
Topological domaini187 – 216CytoplasmicSequence analysisAdd BLAST30
Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
Topological domaini238 – 252PeriplasmicSequence analysisAdd BLAST15
Transmembranei253 – 273HelicalSequence analysisAdd BLAST21
Topological domaini274 – 279CytoplasmicSequence analysis6
Transmembranei280 – 300HelicalSequence analysisAdd BLAST21
Topological domaini301 – 306PeriplasmicSequence analysis6
Transmembranei307 – 327HelicalSequence analysisAdd BLAST21
Topological domaini328 – 340CytoplasmicSequence analysisAdd BLAST13
Transmembranei341 – 361HelicalSequence analysisAdd BLAST21
Topological domaini362 – 363PeriplasmicSequence analysis2
Transmembranei364 – 384HelicalSequence analysisAdd BLAST21
Topological domaini385 – 454CytoplasmicSequence analysisAdd BLAST70

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001734001 – 454Inner membrane transport protein YajRAdd BLAST454

Proteomic databases

PaxDbiP77726.
PRIDEiP77726.

Interactioni

Protein-protein interaction databases

BioGridi4263068. 176 interactors.
STRINGi511145.b0427.

Structurei

3D structure databases

ProteinModelPortaliP77726.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107RDB. Bacteria.
COG0477. LUCA.
HOGENOMiHOG000264695.
InParanoidiP77726.
OMAiPPYVTSL.
PhylomeDBiP77726.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77726-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDYKMTPGE RRATWGLGTV FSLRMLGMFM VLPVLTTYGM ALQGASEALI
60 70 80 90 100
GIAIGIYGLT QAVFQIPFGL LSDRIGRKPL IVGGLAVFAA GSVIAALSDS
110 120 130 140 150
IWGIILGRAL QGSGAIAAAV MALLSDLTRE QNRTKAMAFI GVSFGITFAI
160 170 180 190 200
AMVLGPIITH KLGLHALFWM IAILATTGIA LTIWVVPNSS THVLNRESGM
210 220 230 240 250
VKGSFSKVLA EPRLLKLNFG IMCLHILLMS TFVALPGQLA DAGFPAAEHW
260 270 280 290 300
KVYLATMLIA FGSVVPFIIY AEVKRKMKQV FVFCVGLIVV AEIVLWNAQT
310 320 330 340 350
QFWQLVVGVQ LFFVAFNLME ALLPSLISKE SPAGYKGTAM GVYSTSQFLG
360 370 380 390 400
VAIGGSLGGW INGMFDGQGV FLAGAMLAAV WLTVASTMKE PPYVSSLRIE
410 420 430 440 450
IPANIAANEA LKVRLLETEG IKEVLIAEEE HSAYVKIDSK VTNRFEIEQA

IRQA
Length:454
Mass (Da):48,810
Last modified:April 27, 2001 - v2
Checksum:iB35BD78EE75DE901
GO

Sequence cautioni

The sequence AAB40183 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82664 Genomic DNA. Translation: AAB40183.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73530.2.
AP009048 Genomic DNA. Translation: BAE76207.1.
PIRiC64772.
RefSeqiNP_414961.4. NC_000913.3.
WP_001000963.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73530; AAC73530; b0427.
BAE76207; BAE76207; BAE76207.
GeneIDi945058.
KEGGiecj:JW5059.
eco:b0427.
PATRICi32116005. VBIEscCol129921_0444.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82664 Genomic DNA. Translation: AAB40183.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73530.2.
AP009048 Genomic DNA. Translation: BAE76207.1.
PIRiC64772.
RefSeqiNP_414961.4. NC_000913.3.
WP_001000963.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77726.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263068. 176 interactors.
STRINGi511145.b0427.

Protein family/group databases

TCDBi2.A.1.2.60. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP77726.
PRIDEiP77726.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73530; AAC73530; b0427.
BAE76207; BAE76207; BAE76207.
GeneIDi945058.
KEGGiecj:JW5059.
eco:b0427.
PATRICi32116005. VBIEscCol129921_0444.

Organism-specific databases

EchoBASEiEB3380.
EcoGeneiEG13614. yajR.

Phylogenomic databases

eggNOGiENOG4107RDB. Bacteria.
COG0477. LUCA.
HOGENOMiHOG000264695.
InParanoidiP77726.
OMAiPPYVTSL.
PhylomeDBiP77726.

Enzyme and pathway databases

BioCyciEcoCyc:B0427-MONOMER.
ECOL316407:JW5059-MONOMER.

Miscellaneous databases

PROiP77726.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYAJR_ECOLI
AccessioniPrimary (citable) accession number: P77726
Secondary accession number(s): Q2MBZ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: April 27, 2001
Last modified: November 2, 2016
This is version 109 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.