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Protein

Uncharacterized HTH-type transcriptional regulator YahB

Gene

yahB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi22 – 42H-T-H motifPROSITE-ProRule annotationAdd BLAST21

GO - Molecular functioni

GO - Biological processi

  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6181-MONOMER.
ECOL316407:JW0308-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YahB
Gene namesi
Name:yahB
Ordered Locus Names:b0316, JW0308
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13586. yahB.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001057751 – 310Uncharacterized HTH-type transcriptional regulator YahBAdd BLAST310

Proteomic databases

PaxDbiP77700.
PRIDEiP77700.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
bglGP119893EBI-545731,EBI-545674

Protein-protein interaction databases

BioGridi4262804. 9 interactors.
DIPiDIP-11254N.
IntActiP77700. 6 interactors.
MINTiMINT-1294849.
STRINGi511145.b0316.

Structurei

3D structure databases

ProteinModelPortaliP77700.
SMRiP77700.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 62HTH lysR-typePROSITE-ProRule annotationAdd BLAST58

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108NUU. Bacteria.
ENOG410XQF9. LUCA.
HOGENOMiHOG000181312.
InParanoidiP77700.
OMAiYFYRKAT.
PhylomeDBiP77700.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77700-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSIFTEENL LAFTTAARFG SFSKAAEELG LTTSAISYTI KRMETGLDVV
60 70 80 90 100
LFTRSTRSIE LTESGRYFFR KATDLLNDFY AIKRRIDTIS QGIEARVRIC
110 120 130 140 150
INQLLYTPKH TARLLQVLKK QFPTCQITVT TEVYNGVWDA IINNQANIAI
160 170 180 190 200
GAPDTLLDGG GIDYTEIGAI RWAFAIAPDH PLAFVPEPIA ESQLRLYPNI
210 220 230 240 250
MVEDTAHTIN KKVGWLLHGQ ESILVPDFNT KCQCQILGEG IGFLPDYMVR
260 270 280 290 300
EAMTQSLLVT RQIHNPRQDS RMLLATQHSA TGQVTQWIKK QFAPNGILTG
310
IYQDLLHREN
Length:310
Mass (Da):34,866
Last modified:February 1, 1997 - v1
Checksum:iA3EB895E7F69D60C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA. Translation: AAB18042.1.
U00096 Genomic DNA. Translation: AAC73419.1.
AP009048 Genomic DNA. Translation: BAE76099.1.
PIRiD64758.
RefSeqiNP_414850.1. NC_000913.3.
WP_001084394.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73419; AAC73419; b0316.
BAE76099; BAE76099; BAE76099.
GeneIDi945278.
KEGGiecj:JW0308.
eco:b0316.
PATRICi32115761. VBIEscCol129921_0323.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA. Translation: AAB18042.1.
U00096 Genomic DNA. Translation: AAC73419.1.
AP009048 Genomic DNA. Translation: BAE76099.1.
PIRiD64758.
RefSeqiNP_414850.1. NC_000913.3.
WP_001084394.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77700.
SMRiP77700.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262804. 9 interactors.
DIPiDIP-11254N.
IntActiP77700. 6 interactors.
MINTiMINT-1294849.
STRINGi511145.b0316.

Proteomic databases

PaxDbiP77700.
PRIDEiP77700.

Protocols and materials databases

DNASUi945278.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73419; AAC73419; b0316.
BAE76099; BAE76099; BAE76099.
GeneIDi945278.
KEGGiecj:JW0308.
eco:b0316.
PATRICi32115761. VBIEscCol129921_0323.

Organism-specific databases

EchoBASEiEB3356.
EcoGeneiEG13586. yahB.

Phylogenomic databases

eggNOGiENOG4108NUU. Bacteria.
ENOG410XQF9. LUCA.
HOGENOMiHOG000181312.
InParanoidiP77700.
OMAiYFYRKAT.
PhylomeDBiP77700.

Enzyme and pathway databases

BioCyciEcoCyc:G6181-MONOMER.
ECOL316407:JW0308-MONOMER.

Miscellaneous databases

PROiP77700.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYAHB_ECOLI
AccessioniPrimary (citable) accession number: P77700
Secondary accession number(s): Q2MCA7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.