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Protein

Bactoprenol-linked glucose translocase homolog from prophage CPS-53

Gene

yfdG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity).By similarity

GO - Molecular functioni

  • 5-aminolevulinate synthase activity Source: EcoliWiki
  • catalytic activity Source: EcoliWiki
  • glutamyl-tRNA reductase activity Source: EcoliWiki
  • NADP binding Source: EcoliWiki

GO - Biological processi

  • heme biosynthetic process Source: EcoliWiki
  • polysaccharide biosynthetic process Source: InterPro
  • transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7219-MONOMER.
ECOL316407:JW2346-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Bactoprenol-linked glucose translocase homolog from prophage CPS-53
Gene namesi
Name:yfdG
Ordered Locus Names:b2350, JW2346
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14131. yfdG.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 99CytoplasmicSequence analysis
Transmembranei10 – 3021HelicalSequence analysisAdd
BLAST
Topological domaini31 – 333PeriplasmicSequence analysis
Transmembranei34 – 5421HelicalSequence analysisAdd
BLAST
Topological domaini55 – 6410CytoplasmicSequence analysis
Transmembranei65 – 8521HelicalSequence analysisAdd
BLAST
Topological domaini86 – 883PeriplasmicSequence analysis
Transmembranei89 – 10921HelicalSequence analysisAdd
BLAST
Topological domaini110 – 12011CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 120120Bactoprenol-linked glucose translocase homolog from prophage CPS-53PRO_0000212252Add
BLAST

Proteomic databases

PaxDbiP77682.
PRIDEiP77682.

Interactioni

Protein-protein interaction databases

BioGridi4260541. 149 interactions.
STRINGi511145.b2350.

Structurei

3D structure databases

ProteinModelPortaliP77682.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GtrA family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105IHM. Bacteria.
COG2246. LUCA.
HOGENOMiHOG000005085.
OMAiSTTAMRY.

Family and domain databases

InterProiIPR016480. Glc_translocase_bactprenl-link.
IPR007267. GtrA.
[Graphical view]
PfamiPF04138. GtrA. 1 hit.
[Graphical view]
PIRSFiPIRSF006298. GtrA_prd. 1 hit.

Sequencei

Sequence statusi: Complete.

P77682-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKLFAKYTS IGVLNTLIHW VVFGVCIYVA HTNQALANFA GFVVAVSFSF
60 70 80 90 100
FANAKFTFKA STTTMRYMLY VGFMGTLSAT VGWAADRCAL PPMITLVTFS
110 120
AISLVCGFVY SKFIVFRDAK
Length:120
Mass (Da):13,226
Last modified:February 1, 1997 - v1
Checksum:i881A6B5614875C5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75409.1.
AP009048 Genomic DNA. Translation: BAA16209.1.
PIRiC65008.
RefSeqiNP_416851.1. NC_000913.3.
WP_000915541.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75409; AAC75409; b2350.
BAA16209; BAA16209; BAA16209.
GeneIDi948821.
KEGGiecj:JW2346.
eco:b2350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75409.1.
AP009048 Genomic DNA. Translation: BAA16209.1.
PIRiC65008.
RefSeqiNP_416851.1. NC_000913.3.
WP_000915541.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77682.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260541. 149 interactions.
STRINGi511145.b2350.

Proteomic databases

PaxDbiP77682.
PRIDEiP77682.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75409; AAC75409; b2350.
BAA16209; BAA16209; BAA16209.
GeneIDi948821.
KEGGiecj:JW2346.
eco:b2350.

Organism-specific databases

EchoBASEiEB3883.
EcoGeneiEG14131. yfdG.

Phylogenomic databases

eggNOGiENOG4105IHM. Bacteria.
COG2246. LUCA.
HOGENOMiHOG000005085.
OMAiSTTAMRY.

Enzyme and pathway databases

BioCyciEcoCyc:G7219-MONOMER.
ECOL316407:JW2346-MONOMER.

Miscellaneous databases

PROiP77682.

Family and domain databases

InterProiIPR016480. Glc_translocase_bactprenl-link.
IPR007267. GtrA.
[Graphical view]
PfamiPF04138. GtrA. 1 hit.
[Graphical view]
PIRSFiPIRSF006298. GtrA_prd. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGTRA_ECOLI
AccessioniPrimary (citable) accession number: P77682
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.