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Protein

Prophage bactoprenol-linked glucose translocase homolog

Gene

yfdG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity).By similarity

GO - Molecular functioni

  • 5-aminolevulinate synthase activity Source: EcoliWiki
  • catalytic activity Source: EcoliWiki
  • glutamyl-tRNA reductase activity Source: EcoliWiki
  • NADP binding Source: EcoliWiki

GO - Biological processi

  • heme biosynthetic process Source: EcoliWiki
  • polysaccharide biosynthetic process Source: InterPro

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:G7219-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Prophage bactoprenol-linked glucose translocase homologCurated
Alternative name(s):
Bactoprenol-linked glucose translocase homolog from prophage CPS-53
Gene namesi
Name:yfdG
Ordered Locus Names:b2350, JW2346
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14131 yfdG

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 9CytoplasmicSequence analysis9
Transmembranei10 – 30HelicalSequence analysisAdd BLAST21
Topological domaini31 – 33PeriplasmicSequence analysis3
Transmembranei34 – 54HelicalSequence analysisAdd BLAST21
Topological domaini55 – 64CytoplasmicSequence analysis10
Transmembranei65 – 85HelicalSequence analysisAdd BLAST21
Topological domaini86 – 88PeriplasmicSequence analysis3
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Topological domaini110 – 120CytoplasmicSequence analysisAdd BLAST11

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002122521 – 120Prophage bactoprenol-linked glucose translocase homologAdd BLAST120

Proteomic databases

PaxDbiP77682
PRIDEiP77682

Interactioni

Protein-protein interaction databases

BioGridi4260541, 149 interactors
STRINGi316385.ECDH10B_2513

Structurei

3D structure databases

ProteinModelPortaliP77682
SMRiP77682
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GtrA family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105IHM Bacteria
COG2246 LUCA
HOGENOMiHOG000005085
OMAiSTTAMRY

Family and domain databases

InterProiView protein in InterPro
IPR016480 Glc_translocase_bactprenl-link
IPR007267 GtrA
PfamiView protein in Pfam
PF04138 GtrA, 1 hit
PIRSFiPIRSF006298 GtrA_prd, 1 hit

Sequencei

Sequence statusi: Complete.

P77682-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKLFAKYTS IGVLNTLIHW VVFGVCIYVA HTNQALANFA GFVVAVSFSF
60 70 80 90 100
FANAKFTFKA STTTMRYMLY VGFMGTLSAT VGWAADRCAL PPMITLVTFS
110 120
AISLVCGFVY SKFIVFRDAK
Length:120
Mass (Da):13,226
Last modified:February 1, 1997 - v1
Checksum:i881A6B5614875C5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75409.1
AP009048 Genomic DNA Translation: BAA16209.1
PIRiC65008
RefSeqiNP_416851.1, NC_000913.3
WP_000915541.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75409; AAC75409; b2350
BAA16209; BAA16209; BAA16209
GeneIDi948821
KEGGiecj:JW2346
eco:b2350
PATRICifig|83333.103.peg.3236

Similar proteinsi

Entry informationi

Entry nameiGTRA_ECOLI
AccessioniPrimary (citable) accession number: P77682
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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