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Protein

Protein SufA

Gene

sufA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • iron-sulfur cluster assembly Source: EcoCyc
  • protein maturation by iron-sulfur cluster transfer Source: GO_Central
  • response to oxidative stress Source: EcoCyc
  • sulfur compound metabolic process Source: GO_Central
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11378-MONOMER.
ECOL316407:JW1674-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SufA
Gene namesi
Name:sufA
Synonyms:ydiC
Ordered Locus Names:b1684, JW1674
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11378. sufA.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 122122Protein SufAPRO_0000076987Add
BLAST

Proteomic databases

PaxDbiP77667.
PRIDEiP77667.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
sufBP775225EBI-1125011,EBI-562758
sufCP774995EBI-1125011,EBI-561601

Protein-protein interaction databases

BioGridi4260283. 40 interactions.
IntActiP77667. 8 interactions.
STRINGi511145.b1684.

Structurei

Secondary structure

1
122
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi22 – 3413Combined sources
Beta strandi40 – 489Combined sources
Turni49 – 513Combined sources
Beta strandi52 – 6211Combined sources
Beta strandi67 – 726Combined sources
Beta strandi75 – 806Combined sources
Helixi81 – 833Combined sources
Helixi84 – 874Combined sources
Beta strandi91 – 977Combined sources
Beta strandi100 – 1067Combined sources
Beta strandi119 – 1213Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2D2AX-ray2.70A/B1-122[»]
ProteinModelPortaliP77667.
SMRiP77667. Positions 9-122.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP77667.

Family & Domainsi

Sequence similaritiesi

Belongs to the HesB/IscA family.Curated

Phylogenomic databases

eggNOGiENOG4108Z4V. Bacteria.
COG0316. LUCA.
HOGENOMiHOG000228314.
InParanoidiP77667.
KOiK05997.
OMAiDFAWRGL.
OrthoDBiEOG6VXF8J.
PhylomeDBiP77667.

Family and domain databases

Gene3Di2.60.300.12. 1 hit.
InterProiIPR000361. FeS_biogenesis.
IPR016092. FeS_cluster_insertion.
IPR017870. FeS_cluster_insertion_CS.
IPR011298. SufA_proteobacteria.
[Graphical view]
PfamiPF01521. Fe-S_biosyn. 1 hit.
[Graphical view]
SUPFAMiSSF89360. SSF89360. 1 hit.
TIGRFAMsiTIGR01997. sufA_proteo. 1 hit.
TIGR00049. TIGR00049. 1 hit.
PROSITEiPS01152. HESB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77667-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMHSGTFNP QDFAWQGLTL TPAAAIHIRE LVAKQPGMVG VRLGVKQTGC
60 70 80 90 100
AGFGYVLDSV SEPDKDDLLF EHDGAKLFVP LQAMPFIDGT EVDFVREGLN
110 120
QIFKFHNPKA QNECGCGESF GV
Length:122
Mass (Da):13,300
Last modified:February 1, 1997 - v1
Checksum:iD26817F42E4B740B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74754.1.
AP009048 Genomic DNA. Translation: BAA15453.1.
PIRiD64926.
RefSeqiNP_416199.1. NC_000913.3.
WP_000367160.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74754; AAC74754; b1684.
BAA15453; BAA15453; BAA15453.
GeneIDi949014.
KEGGiecj:JW1674.
eco:b1684.
PATRICi32118674. VBIEscCol129921_1755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74754.1.
AP009048 Genomic DNA. Translation: BAA15453.1.
PIRiD64926.
RefSeqiNP_416199.1. NC_000913.3.
WP_000367160.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2D2AX-ray2.70A/B1-122[»]
ProteinModelPortaliP77667.
SMRiP77667. Positions 9-122.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260283. 40 interactions.
IntActiP77667. 8 interactions.
STRINGi511145.b1684.

Proteomic databases

PaxDbiP77667.
PRIDEiP77667.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74754; AAC74754; b1684.
BAA15453; BAA15453; BAA15453.
GeneIDi949014.
KEGGiecj:JW1674.
eco:b1684.
PATRICi32118674. VBIEscCol129921_1755.

Organism-specific databases

EchoBASEiEB1352.
EcoGeneiEG11378. sufA.

Phylogenomic databases

eggNOGiENOG4108Z4V. Bacteria.
COG0316. LUCA.
HOGENOMiHOG000228314.
InParanoidiP77667.
KOiK05997.
OMAiDFAWRGL.
OrthoDBiEOG6VXF8J.
PhylomeDBiP77667.

Enzyme and pathway databases

BioCyciEcoCyc:EG11378-MONOMER.
ECOL316407:JW1674-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP77667.
PROiP77667.

Family and domain databases

Gene3Di2.60.300.12. 1 hit.
InterProiIPR000361. FeS_biogenesis.
IPR016092. FeS_cluster_insertion.
IPR017870. FeS_cluster_insertion_CS.
IPR011298. SufA_proteobacteria.
[Graphical view]
PfamiPF01521. Fe-S_biosyn. 1 hit.
[Graphical view]
SUPFAMiSSF89360. SSF89360. 1 hit.
TIGRFAMsiTIGR01997. sufA_proteo. 1 hit.
TIGR00049. TIGR00049. 1 hit.
PROSITEiPS01152. HESB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "SufS is a NifS-like protein, and SufD is necessary for stability of the 2Fe-2S FhuF protein in Escherichia coli."
    Patzer S.I., Hantke K.
    J. Bacteriol. 181:3307-3309(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE NAME.
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiSUFA_ECOLI
AccessioniPrimary (citable) accession number: P77667
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: January 20, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.