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Protein

UPF0214 protein YfeW

Gene

yfeW

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • penicillin binding Source: EcoCyc
  • serine-type D-Ala-D-Ala carboxypeptidase activity Source: EcoCyc

GO - Biological processi

  • proteolysis Source: GOC
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7265-MONOMER.
ECOL316407:JW5395-MONOMER.
MetaCyc:G7265-MONOMER.

Protein family/group databases

MEROPSiS12.A03.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0214 protein YfeW
Gene namesi
Name:yfeW
Ordered Locus Names:b2430, JW5395
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14164. yfeW.

Subcellular locationi

GO - Cellular componenti

  • intrinsic component of plasma membrane Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 434415UPF0214 protein YfeWPRO_0000036256Add
BLAST

Proteomic databases

PaxDbiP77619.
PRIDEiP77619.

Interactioni

Protein-protein interaction databases

BioGridi4260747. 305 interactions.
DIPiDIP-12021N.
STRINGi511145.b2430.

Structurei

3D structure databases

ProteinModelPortaliP77619.
SMRiP77619. Positions 42-348.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0214 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107S1E. Bacteria.
COG1680. LUCA.
HOGENOMiHOG000008712.
InParanoidiP77619.
OMAiGHKSTIV.
OrthoDBiEOG6CZQN4.
PhylomeDBiP77619.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_01034. UPF0214.
InterProiIPR001466. Beta-lactam-related.
IPR012338. Beta-lactam/transpept-like.
IPR022849. Pept_S12_UPF0214_YfeW-type.
[Graphical view]
PfamiPF00144. Beta-lactamase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P77619-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRTMLYLSL LAVSCSVSAA KYPVLTESSP EKAGFNVERL NQMDRWISQQ
60 70 80 90 100
VDVGYPSVNL LIIKDNQIVY RKAWGAAKKY DGSVLMEQPV KATTGTLYDL
110 120 130 140 150
ASNTKMYATN FALQKLMSEG KLHPDDRIAK YIPGFADSPN DTIKGKNTLR
160 170 180 190 200
ISDLLHHSGG FPADPQYPNK AVAGALYSQD KGQTLEMIKR TPLEYQPGSK
210 220 230 240 250
HIYSDVDYML LGFIVESVTG QPLDRYVEES IYRPLGLTHT VFNPLLKGFK
260 270 280 290 300
PQQIAATELN GNTRDGVIHF PNIRTSTLWG QVHDEKAFYS MGGVSGHAGL
310 320 330 340 350
FSNTGDIAVL MQTMLNGGGY GDVQLFNAET VKMFTTSSKE DATFGLGWRV
360 370 380 390 400
NGNATMTPTF GTLASPQTYG HTGWTGTVTV IDPVNHMTIV MLSNKPHSPV
410 420 430
ADPQKNPNMF ESGQLPIATY GWVVDQVYAA LKQK
Length:434
Mass (Da):47,752
Last modified:December 15, 1998 - v2
Checksum:i9CA0FDA5347A5468
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75483.2.
AP009048 Genomic DNA. Translation: BAA16314.2.
PIRiE65017.
RefSeqiNP_416925.2. NC_000913.3.
WP_001327042.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75483; AAC75483; b2430.
BAA16314; BAA16314; BAA16314.
GeneIDi946907.
KEGGiecj:JW5395.
eco:b2430.
PATRICi32120245. VBIEscCol129921_2525.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75483.2.
AP009048 Genomic DNA. Translation: BAA16314.2.
PIRiE65017.
RefSeqiNP_416925.2. NC_000913.3.
WP_001327042.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77619.
SMRiP77619. Positions 42-348.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260747. 305 interactions.
DIPiDIP-12021N.
STRINGi511145.b2430.

Protein family/group databases

MEROPSiS12.A03.

Proteomic databases

PaxDbiP77619.
PRIDEiP77619.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75483; AAC75483; b2430.
BAA16314; BAA16314; BAA16314.
GeneIDi946907.
KEGGiecj:JW5395.
eco:b2430.
PATRICi32120245. VBIEscCol129921_2525.

Organism-specific databases

EchoBASEiEB3916.
EcoGeneiEG14164. yfeW.

Phylogenomic databases

eggNOGiENOG4107S1E. Bacteria.
COG1680. LUCA.
HOGENOMiHOG000008712.
InParanoidiP77619.
OMAiGHKSTIV.
OrthoDBiEOG6CZQN4.
PhylomeDBiP77619.

Enzyme and pathway databases

BioCyciEcoCyc:G7265-MONOMER.
ECOL316407:JW5395-MONOMER.
MetaCyc:G7265-MONOMER.

Miscellaneous databases

PROiP77619.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_01034. UPF0214.
InterProiIPR001466. Beta-lactam-related.
IPR012338. Beta-lactam/transpept-like.
IPR022849. Pept_S12_UPF0214_YfeW-type.
[Graphical view]
PfamiPF00144. Beta-lactamase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYFEW_ECOLI
AccessioniPrimary (citable) accession number: P77619
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: December 15, 1998
Last modified: January 20, 2016
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.