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Protein

Ion-translocating oxidoreductase complex subunit C

Gene

rsxC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity). Required to maintain the reduced state of SoxR. Probably transfers electron from NAD(P)H to SoxR (PubMed:12773378).UniRule annotation1 Publication

Cofactori

[4Fe-4S] clusterUniRule annotationNote: Binds 2 [4Fe-4S] clusters per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi377Iron-sulfur 1 (4Fe-4S)UniRule annotation1
Metal bindingi380Iron-sulfur 1 (4Fe-4S)UniRule annotation1
Metal bindingi383Iron-sulfur 1 (4Fe-4S)UniRule annotation1
Metal bindingi387Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi416Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi419Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi422Iron-sulfur 2 (4Fe-4S)UniRule annotation1
Metal bindingi426Iron-sulfur 1 (4Fe-4S)UniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Transport
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6873-MONOMER

Protein family/group databases

TCDBi3.D.6.1.4 the putative ion (h(+) or na(+))-translocating nadh:ferredoxin oxidoreductase (nfo or rnf) family

Names & Taxonomyi

Protein namesi
Recommended name:
Ion-translocating oxidoreductase complex subunit CUniRule annotationCurated (EC:1.18.1.-UniRule annotationCurated)
Alternative name(s):
Rsx electron transport complex subunit CUniRule annotationCurated
Gene namesi
Name:rsxC1 PublicationUniRule annotation
Synonyms:rnfC, ydgN
Ordered Locus Names:b1629, JW1621
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13935 rsxC

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000732051 – 740Ion-translocating oxidoreductase complex subunit CAdd BLAST740

Proteomic databases

PaxDbiP77611
PRIDEiP77611

Interactioni

Subunit structurei

The complex is composed of six subunits: RsxA, RsxB, RsxC, RsxD, RsxE and RsxG.UniRule annotation1 Publication

Protein-protein interaction databases

BioGridi4261728, 153 interactors
DIPiDIP-28084N
IntActiP77611, 4 interactors
STRINGi316385.ECDH10B_1763

Structurei

3D structure databases

ProteinModelPortaliP77611
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini369 – 3974Fe-4S ferredoxin-type 1UniRule annotationAdd BLAST29
Domaini407 – 4364Fe-4S ferredoxin-type 2UniRule annotationAdd BLAST30

Sequence similaritiesi

Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4107QTR Bacteria
COG4656 LUCA
HOGENOMiHOG000279299
InParanoidiP77611
KOiK03615
OMAiQQLYWYS
PhylomeDBiP77611

Family and domain databases

Gene3Di1.10.1060.10, 1 hit
3.40.50.11540, 1 hit
HAMAPiMF_00461 RsxC_RnfC, 1 hit
InterProiView protein in InterPro
IPR017896 4Fe4S_Fe-S-bd
IPR017900 4Fe4S_Fe_S_CS
IPR010208 Elect_transpt_RnfC/RsxC
IPR009051 Helical_ferredxn
IPR011538 Nuo51_FMN-bd
IPR037225 Nuo51_FMN-bd_sf
IPR026902 RnfC_N
IPR019554 Soluble_ligand-bd
PANTHERiPTHR43034 PTHR43034, 3 hits
PfamiView protein in Pfam
PF01512 Complex1_51K, 1 hit
PF12838 Fer4_7, 1 hit
PF13375 RnfC_N, 1 hit
PF10531 SLBB, 1 hit
SUPFAMiSSF142019 SSF142019, 1 hit
SSF46548 SSF46548, 1 hit
TIGRFAMsiTIGR01945 rnfC, 1 hit
PROSITEiView protein in PROSITE
PS00198 4FE4S_FER_1, 2 hits
PS51379 4FE4S_FER_2, 2 hits

Sequencei

Sequence statusi: Complete.

P77611-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKLFSAFRK NKIWDFNGGI HPPEMKTQSN GTPLRQVPLA QRFVIPLKQH
60 70 80 90 100
IGAEGELCVS VGDKVLRGQP LTRGRGKMLP VHAPTSGTVT AIAPHSTAHP
110 120 130 140 150
SALAELSVII DADGEDCWIP RDGWADYRTR SREELIERIH QFGVAGLGGA
160 170 180 190 200
GFPTGVKLQG GGDKIETLII NAAECEPYIT ADDRLMQDCA AQVVEGIRIL
210 220 230 240 250
AHILQPREIL IGIEDNKPQA ISMLRAVLAD SNDISLRVIP TKYPSGGAKQ
260 270 280 290 300
LTYILTGKQV PHGGRSSDIG VLMQNVGTAY AVKRAVIDGE PITERVVTLT
310 320 330 340 350
GEAIARPGNV WARLGTPVRH LLNDAGFCPS ADQMVIMGGP LMGFTLPWLD
360 370 380 390 400
VPVVKITNCL LAPSANELGE PQEEQSCIRC SACADACPAD LLPQQLYWFS
410 420 430 440 450
KGQQHDKATT HNIADCIECG ACAWVCPSNI PLVQYFRQEK AEIAAIRQEE
460 470 480 490 500
KRAAEAKARF EARQARLERE KAARLERHKS AAVQPAAKDK DAIAAALARV
510 520 530 540 550
KEKQAQATQP IVIKAGERPD NSAIIAAREA RKAQARAKQA ELQQTNDAAT
560 570 580 590 600
VADPRKTAVE AAIARAKARK LEQQQANAEP EQQVDPRKAA VEAAIARAKA
610 620 630 640 650
RKLEQQQANA EPEEQVDPRK AAVEAAIARA KARKLEQQQA NAEPEQQVDP
660 670 680 690 700
RKAAVEAAIA RAKARKREQQ PANAEPEEQV DPRKAAVEAA IARAKARKLE
710 720 730 740
QQQANAVPEE QVDPRKAAVA AAIARAQAKK AAQQKVVNED
Length:740
Mass (Da):80,172
Last modified:February 1, 1997 - v1
Checksum:i381506475CD6E01F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74701.1
AP009048 Genomic DNA Translation: BAA15384.1
PIRiG64919
RefSeqiNP_416146.1, NC_000913.3
WP_000915778.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74701; AAC74701; b1629
BAA15384; BAA15384; BAA15384
GeneIDi946137
KEGGiecj:JW1621
eco:b1629
PATRICifig|1411691.4.peg.632

Similar proteinsi

Entry informationi

Entry nameiRSXC_ECOLI
AccessioniPrimary (citable) accession number: P77611
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2001
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 157 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health