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Protein

L-asparagine permease

Gene

ansP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:ANSP-MONOMER.
ECOL316407:JW5234-MONOMER.

Protein family/group databases

TCDBi2.A.3.1.24. the amino acid-polyamine-organocation (apc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
L-asparagine permease
Alternative name(s):
L-asparagine transport protein
Gene namesi
Name:ansP
Synonyms:yncF
Ordered Locus Names:b1453, JW5234
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13776. ansP.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei34 – 5421HelicalSequence analysisAdd
BLAST
Transmembranei58 – 7821HelicalSequence analysisAdd
BLAST
Transmembranei109 – 12921HelicalSequence analysisAdd
BLAST
Transmembranei146 – 16621HelicalSequence analysisAdd
BLAST
Transmembranei171 – 19121HelicalSequence analysisAdd
BLAST
Transmembranei219 – 23921HelicalSequence analysisAdd
BLAST
Transmembranei264 – 28421HelicalSequence analysisAdd
BLAST
Transmembranei298 – 31821HelicalSequence analysisAdd
BLAST
Transmembranei353 – 37321HelicalSequence analysisAdd
BLAST
Transmembranei378 – 39821HelicalSequence analysisAdd
BLAST
Transmembranei422 – 44221HelicalSequence analysisAdd
BLAST
Transmembranei448 – 46821HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 499499L-asparagine permeasePRO_0000054185Add
BLAST

Proteomic databases

PaxDbiP77610.
PRIDEiP77610.

Interactioni

Protein-protein interaction databases

BioGridi4260199. 8 interactions.
STRINGi511145.b1453.

Structurei

3D structure databases

ProteinModelPortaliP77610.
SMRiP77610. Positions 35-357.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C85. Bacteria.
COG1113. LUCA.
HOGENOMiHOG000261847.
InParanoidiP77610.
KOiK11738.
OMAiGELIMHR.
OrthoDBiEOG6HQSQM.
PhylomeDBiP77610.

Family and domain databases

InterProiIPR004841. AA-permease/SLC12A_dom.
IPR002293. AA/rel_permease1.
IPR004840. Amoino_acid_permease_CS.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF00324. AA_permease. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.
PROSITEiPS00218. AMINO_ACID_PERMEASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77610-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKHDTDTSD QHAAKRRWLN AHEEGYHKAM GNRQVQMIAI GGAIGTGLFL
60 70 80 90 100
GAGARLQMAG PALALVYLIC GLFSFFILRA LGELVLHRPS SGSFVSYARE
110 120 130 140 150
FLGEKAAYVA GWMYFINWAM TGIVDITAVA LYMHYWGAFG GVPQWVFALA
160 170 180 190 200
ALTIVGTMNM IGVKWFAEME FWFALIKVLA IVTFLVVGTV FLGSGQPLDG
210 220 230 240 250
NTTGFHLITD NGGFFPHGLL PALVLIQGVV FAFASIEMVG TAAGECKDPQ
260 270 280 290 300
TMVPKAINSV IWRIGLFYVG SVVLLVMLLP WSAYQAGQSP FVTFFSKLGV
310 320 330 340 350
PYIGSIMNIV VLTAALSSLN SGLYCTGRIL RSMAMGGSAP SFMAKMSRQH
360 370 380 390 400
VPYAGILATL VVYVVGVFLN YLVPSRVFEI VLNFASLGII ASWAFIIVCQ
410 420 430 440 450
MRLRKAIKEG KAADVSFKLP GAPFTSWLTL LFLLSVLVLM AFDYPNGTYT
460 470 480 490
IAALPIIGIL LVIGWFGVRK RVAEIHSTAP VVEEDEEKQE IVFKPETAS
Length:499
Mass (Da):54,233
Last modified:July 15, 1998 - v2
Checksum:i188948BD8EC662E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74535.2.
AP009048 Genomic DNA. Translation: BAA15086.2.
RefSeqiNP_415970.4. NC_000913.3.
WP_001300590.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74535; AAC74535; b1453.
BAA15086; BAA15086; BAA15086.
GeneIDi946019.
KEGGiecj:JW5234.
eco:b1453.
PATRICi32118198. VBIEscCol129921_1519.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74535.2.
AP009048 Genomic DNA. Translation: BAA15086.2.
RefSeqiNP_415970.4. NC_000913.3.
WP_001300590.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77610.
SMRiP77610. Positions 35-357.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260199. 8 interactions.
STRINGi511145.b1453.

Protein family/group databases

TCDBi2.A.3.1.24. the amino acid-polyamine-organocation (apc) family.

Proteomic databases

PaxDbiP77610.
PRIDEiP77610.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74535; AAC74535; b1453.
BAA15086; BAA15086; BAA15086.
GeneIDi946019.
KEGGiecj:JW5234.
eco:b1453.
PATRICi32118198. VBIEscCol129921_1519.

Organism-specific databases

EchoBASEiEB3538.
EcoGeneiEG13776. ansP.

Phylogenomic databases

eggNOGiENOG4105C85. Bacteria.
COG1113. LUCA.
HOGENOMiHOG000261847.
InParanoidiP77610.
KOiK11738.
OMAiGELIMHR.
OrthoDBiEOG6HQSQM.
PhylomeDBiP77610.

Enzyme and pathway databases

BioCyciEcoCyc:ANSP-MONOMER.
ECOL316407:JW5234-MONOMER.

Miscellaneous databases

PROiP77610.

Family and domain databases

InterProiIPR004841. AA-permease/SLC12A_dom.
IPR002293. AA/rel_permease1.
IPR004840. Amoino_acid_permease_CS.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF00324. AA_permease. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.
PROSITEiPS00218. AMINO_ACID_PERMEASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiANSP_ECOLI
AccessioniPrimary (citable) accession number: P77610
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 15, 1998
Last modified: February 17, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.