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Protein

Uncharacterized HTH-type transcriptional regulator YnfL

Gene

ynfL

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi20 – 40H-T-H motifPROSITE-ProRule annotationAdd BLAST21

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6853-MONOMER.
ECOL316407:JW1587-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YnfL
Gene namesi
Name:ynfL
Ordered Locus Names:b1595, JW1587
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13850. ynfL.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001058091 – 297Uncharacterized HTH-type transcriptional regulator YnfLAdd BLAST297

Proteomic databases

PaxDbiP77559.
PRIDEiP77559.

Interactioni

Protein-protein interaction databases

BioGridi4259120. 11 interactors.
DIPiDIP-12771N.
IntActiP77559. 1 interactor.
STRINGi511145.b1595.

Structurei

3D structure databases

ProteinModelPortaliP77559.
SMRiP77559.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 60HTH lysR-typePROSITE-ProRule annotationAdd BLAST60

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4106NZI. Bacteria.
ENOG410YGF0. LUCA.
HOGENOMiHOG000233514.
InParanoidiP77559.
OMAiDAISEMW.
PhylomeDBiP77559.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77559-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIELRHLRY FVAVAEELHF GRAAARLNIS QPPLSQQIQA LEQQIGARLL
60 70 80 90 100
ARTNRSVLLT AAGKQFLADS RQILSMVDDA AARAERLHQG EAGELRIGFT
110 120 130 140 150
SSAPFIRAVS DTLSLFRRDY PDVHLQTREM NTREQIAPLI EGTLDMGLLR
160 170 180 190 200
NTALPESLEH AVIVHEPLMA MIPHDHPLAN NPNVTLAELA KEPFVFFDPH
210 220 230 240 250
VGTGLYDDIL GLMRRYHLTP VITQEVGEAM TIIGLVSAGL GVSILPASFK
260 270 280 290
RVQLNEMRWV PIAEEDAVSE MWLVWPKHHE QSPAARNFRI HLLNALR
Length:297
Mass (Da):33,281
Last modified:February 1, 1997 - v1
Checksum:i7D110818B677EF3D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74667.1.
AP009048 Genomic DNA. Translation: BAA15319.1.
PIRiE64915.
RefSeqiNP_416112.1. NC_000913.3.
WP_001019525.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74667; AAC74667; b1595.
BAA15319; BAA15319; BAA15319.
GeneIDi946136.
KEGGiecj:JW1587.
eco:b1595.
PATRICi32118492. VBIEscCol129921_1666.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74667.1.
AP009048 Genomic DNA. Translation: BAA15319.1.
PIRiE64915.
RefSeqiNP_416112.1. NC_000913.3.
WP_001019525.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77559.
SMRiP77559.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259120. 11 interactors.
DIPiDIP-12771N.
IntActiP77559. 1 interactor.
STRINGi511145.b1595.

Proteomic databases

PaxDbiP77559.
PRIDEiP77559.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74667; AAC74667; b1595.
BAA15319; BAA15319; BAA15319.
GeneIDi946136.
KEGGiecj:JW1587.
eco:b1595.
PATRICi32118492. VBIEscCol129921_1666.

Organism-specific databases

EchoBASEiEB3611.
EcoGeneiEG13850. ynfL.

Phylogenomic databases

eggNOGiENOG4106NZI. Bacteria.
ENOG410YGF0. LUCA.
HOGENOMiHOG000233514.
InParanoidiP77559.
OMAiDAISEMW.
PhylomeDBiP77559.

Enzyme and pathway databases

BioCyciEcoCyc:G6853-MONOMER.
ECOL316407:JW1587-MONOMER.

Miscellaneous databases

PROiP77559.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYNFL_ECOLI
AccessioniPrimary (citable) accession number: P77559
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.