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Protein

UPF0226 protein YfcJ

Gene

yfcJ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:B2322-MONOMER.
ECOL316407:JW2319-MONOMER.

Protein family/group databases

TCDBi2.A.1.46.6. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0226 protein YfcJ
Gene namesi
Name:yfcJ
Ordered Locus Names:b2322, JW2319
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14113. yfcJ.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1919CytoplasmicSequence analysisAdd
BLAST
Transmembranei20 – 4223HelicalSequence analysisAdd
BLAST
Topological domaini43 – 519PeriplasmicSequence analysis
Transmembranei52 – 7120HelicalSequence analysisAdd
BLAST
Topological domaini72 – 8211CytoplasmicSequence analysisAdd
BLAST
Transmembranei83 – 10523HelicalSequence analysisAdd
BLAST
Topological domaini106 – 11914PeriplasmicSequence analysisAdd
BLAST
Transmembranei120 – 14223HelicalSequence analysisAdd
BLAST
Topological domaini143 – 1486CytoplasmicSequence analysis
Transmembranei149 – 17123HelicalSequence analysisAdd
BLAST
Topological domaini172 – 1754PeriplasmicSequence analysis
Transmembranei176 – 19823HelicalSequence analysisAdd
BLAST
Topological domaini199 – 20911CytoplasmicSequence analysisAdd
BLAST
Transmembranei210 – 23223HelicalSequence analysisAdd
BLAST
Topological domaini233 – 24614PeriplasmicSequence analysisAdd
BLAST
Transmembranei247 – 26923HelicalSequence analysisAdd
BLAST
Topological domaini270 – 2756CytoplasmicSequence analysis
Transmembranei276 – 29823HelicalSequence analysisAdd
BLAST
Topological domaini299 – 3024PeriplasmicSequence analysis
Transmembranei303 – 32523HelicalSequence analysisAdd
BLAST
Topological domaini326 – 33712CytoplasmicSequence analysisAdd
BLAST
Transmembranei338 – 36023HelicalSequence analysisAdd
BLAST
Topological domaini361 – 3699PeriplasmicSequence analysis
Transmembranei370 – 38920HelicalSequence analysisAdd
BLAST
Topological domaini390 – 3923CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 392392UPF0226 protein YfcJPRO_0000087801Add
BLAST

Proteomic databases

PaxDbiP77549.
PRIDEiP77549.

Interactioni

Protein-protein interaction databases

BioGridi4260717. 222 interactions.
IntActiP77549. 1 interaction.
STRINGi511145.b2322.

Structurei

3D structure databases

ProteinModelPortaliP77549.
SMRiP77549. Positions 35-384.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0226 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105F9N. Bacteria.
ENOG410XNX3. LUCA.
HOGENOMiHOG000122488.
InParanoidiP77549.
OMAiNGWPMAG.
OrthoDBiEOG6S268F.
PhylomeDBiP77549.

Family and domain databases

HAMAPiMF_01118. UPF0226.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023008. UPF0226_MFS.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77549-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAVSQTETR SSANFSLFRI AFAVFLTYMT VGLPLPVIPL FVHHELGYGN
60 70 80 90 100
TMVGIAVGIQ FLATVLTRGY AGRLADQYGA KRSALQGMLA CGLAGGALLL
110 120 130 140 150
AAILPVSAPF KFALLVVGRL ILGFGESQLL TGALTWGLGI VGPKHSGKVM
160 170 180 190 200
SWNGMAIYGA LAVGAPLGLL IHSHYGFAAL AITTMVLPVL AWACNGTVRK
210 220 230 240 250
VPALAGERPS LWSVVGLIWK PGLGLALQGV GFAVIGTFVS LYFASKGWAM
260 270 280 290 300
AGFTLTAFGG AFVVMRVMFG WMPDRFGGVK VAIVSLLVET VGLLLLWQAP
310 320 330 340 350
GAWVALAGAA LTGAGCSLIF PALGVEVVKR VPSQVRGTAL GGYAAFQDIA
360 370 380 390
LGVSGPLAGM LATTFGYSSV FLAGAISAVL GIIVTILSFR RG
Length:392
Mass (Da):40,465
Last modified:February 1, 1997 - v1
Checksum:i0F0E23ABAA9009E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U76961 Genomic DNA. Translation: AAB36528.1.
U00096 Genomic DNA. Translation: AAC75382.1.
AP009048 Genomic DNA. Translation: BAA16179.1.
PIRiH65004.
RefSeqiNP_416825.1. NC_000913.3.
WP_000127781.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75382; AAC75382; b2322.
BAA16179; BAA16179; BAA16179.
GeneIDi946791.
KEGGiecj:JW2319.
eco:b2322.
PATRICi32120017. VBIEscCol129921_2418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U76961 Genomic DNA. Translation: AAB36528.1.
U00096 Genomic DNA. Translation: AAC75382.1.
AP009048 Genomic DNA. Translation: BAA16179.1.
PIRiH65004.
RefSeqiNP_416825.1. NC_000913.3.
WP_000127781.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77549.
SMRiP77549. Positions 35-384.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260717. 222 interactions.
IntActiP77549. 1 interaction.
STRINGi511145.b2322.

Protein family/group databases

TCDBi2.A.1.46.6. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP77549.
PRIDEiP77549.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75382; AAC75382; b2322.
BAA16179; BAA16179; BAA16179.
GeneIDi946791.
KEGGiecj:JW2319.
eco:b2322.
PATRICi32120017. VBIEscCol129921_2418.

Organism-specific databases

EchoBASEiEB3866.
EcoGeneiEG14113. yfcJ.

Phylogenomic databases

eggNOGiENOG4105F9N. Bacteria.
ENOG410XNX3. LUCA.
HOGENOMiHOG000122488.
InParanoidiP77549.
OMAiNGWPMAG.
OrthoDBiEOG6S268F.
PhylomeDBiP77549.

Enzyme and pathway databases

BioCyciEcoCyc:B2322-MONOMER.
ECOL316407:JW2319-MONOMER.

Miscellaneous databases

PROiP77549.

Family and domain databases

HAMAPiMF_01118. UPF0226.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023008. UPF0226_MFS.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence from fabB to pdxB."
    Pease A.J., Schoenlein P.V., Winkler M.E.
    Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYFCJ_ECOLI
AccessioniPrimary (citable) accession number: P77549
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: February 1, 1997
Last modified: January 20, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.