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P77549 (YFCJ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UPF0226 protein YfcJ
Gene names
Name:yfcJ
Ordered Locus Names:b2322, JW2319
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length392 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cell inner membrane; Multi-pass membrane protein HAMAP-Rule MF_01118.

Sequence similarities

Belongs to the UPF0226 family.

Ontologies

Keywords
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtransmembrane transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 392392UPF0226 protein YfcJ HAMAP-Rule MF_01118
PRO_0000087801

Regions

Topological domain1 – 1919Cytoplasmic Potential
Transmembrane20 – 4223Helical; Potential
Topological domain43 – 519Periplasmic Potential
Transmembrane52 – 7120Helical; Potential
Topological domain72 – 8211Cytoplasmic Potential
Transmembrane83 – 10523Helical; Potential
Topological domain106 – 11914Periplasmic Potential
Transmembrane120 – 14223Helical; Potential
Topological domain143 – 1486Cytoplasmic Potential
Transmembrane149 – 17123Helical; Potential
Topological domain172 – 1754Periplasmic Potential
Transmembrane176 – 19823Helical; Potential
Topological domain199 – 20911Cytoplasmic Potential
Transmembrane210 – 23223Helical; Potential
Topological domain233 – 24614Periplasmic Potential
Transmembrane247 – 26923Helical; Potential
Topological domain270 – 2756Cytoplasmic Potential
Transmembrane276 – 29823Helical; Potential
Topological domain299 – 3024Periplasmic Potential
Transmembrane303 – 32523Helical; Potential
Topological domain326 – 33712Cytoplasmic Potential
Transmembrane338 – 36023Helical; Potential
Topological domain361 – 3699Periplasmic Potential
Transmembrane370 – 38920Helical; Potential
Topological domain390 – 3923Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P77549 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 0F0E23ABAA9009E4

FASTA39240,465
        10         20         30         40         50         60 
MTAVSQTETR SSANFSLFRI AFAVFLTYMT VGLPLPVIPL FVHHELGYGN TMVGIAVGIQ 

        70         80         90        100        110        120 
FLATVLTRGY AGRLADQYGA KRSALQGMLA CGLAGGALLL AAILPVSAPF KFALLVVGRL 

       130        140        150        160        170        180 
ILGFGESQLL TGALTWGLGI VGPKHSGKVM SWNGMAIYGA LAVGAPLGLL IHSHYGFAAL 

       190        200        210        220        230        240 
AITTMVLPVL AWACNGTVRK VPALAGERPS LWSVVGLIWK PGLGLALQGV GFAVIGTFVS 

       250        260        270        280        290        300 
LYFASKGWAM AGFTLTAFGG AFVVMRVMFG WMPDRFGGVK VAIVSLLVET VGLLLLWQAP 

       310        320        330        340        350        360 
GAWVALAGAA LTGAGCSLIF PALGVEVVKR VPSQVRGTAL GGYAAFQDIA LGVSGPLAGM 

       370        380        390 
LATTFGYSSV FLAGAISAVL GIIVTILSFR RG

« Hide

References

« Hide 'large scale' references
[1]"Sequence from fabB to pdxB."
Pease A.J., Schoenlein P.V., Winkler M.E.
Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T. expand/collapse author list , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: K12 / MG1655 / ATCC 47076.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U76961 Genomic DNA. Translation: AAB36528.1.
U00096 Genomic DNA. Translation: AAC75382.1.
AP009048 Genomic DNA. Translation: BAA16179.1.
PIRH65004.
RefSeqNP_416825.1. NC_000913.2.
YP_490564.1. NC_007779.1.

3D structure databases

ProteinModelPortalP77549.
ModBaseSearch...

Proteomic databases

PRIDEP77549.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC75382; AAC75382; b2322.
BAA16179; BAA16179; BAA16179.
GeneID12931723.
946791.
KEGGecj:Y75_p2288.
eco:b2322.
PATRIC32120017. VBIEscCol129921_2418.

Organism-specific databases

EchoBASEEB3866.
EcoGeneEG14113. yfcJ.

Phylogenomic databases

eggNOGNOG242435.
HOGENOMHOG000122488.
OMASYGYPSV.
ProtClustDBPRK12382.

Enzyme and pathway databases

BioCycEcoCyc:B2322-MONOMER.
ECOL316407:JW2319-MONOMER.

Gene expression databases

GenevestigatorP77549.

Family and domain databases

HAMAPMF_01118. UPF0226.
InterProIPR011701. MFS.
IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR023008. UPF0226_MFS.
[Graphical view]
PfamPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMSSF103473. MFS_gen_substrate_transporter. 1 hit.
PROSITEPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYFCJ_ECOLI
AccessionPrimary (citable) accession number: P77549
Entry history
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: February 1, 1997
Last modified: May 1, 2013
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents