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Protein

Uncharacterized protein YfhR

Gene

yfhR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G7328-MONOMER.
ECOL316407:JW2518-MONOMER.

Protein family/group databases

ESTHERiecoli-YfhR. ABHD13-BEM46.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YfhR
Gene namesi
Name:yfhR
Ordered Locus Names:b2534, JW2518
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13453. yfhR.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3221HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 284284Uncharacterized protein YfhRPRO_0000169252Add
BLAST

Proteomic databases

PaxDbiP77538.
PRIDEiP77538.

Interactioni

Protein-protein interaction databases

BioGridi4260968. 19 interactions.
IntActiP77538. 5 interactions.
STRINGi511145.b2534.

Structurei

3D structure databases

ProteinModelPortaliP77538.
SMRiP77538. Positions 210-260.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serine esterase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107XM9. Bacteria.
COG1073. LUCA.
HOGENOMiHOG000007143.
InParanoidiP77538.
KOiK06889.
OrthoDBiEOG6677RW.
PhylomeDBiP77538.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR022742. Hydrolase_4.
[Graphical view]
PfamiPF12146. Hydrolase_4. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

P77538-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALPVNKRVP KILFILFVVA FCVYLVPRVA INFFYYPDDK IYGPDPWSAE
60 70 80 90 100
SVEFTAKDGT RLQGWFIPSS TGPADNAIAT IIHAHGNAGN MSAHWPLVSW
110 120 130 140 150
LPERNFNVFM FDYRGFGKSK GTPSQAGLLD DTQSAINVVR HRSDVNPQRL
160 170 180 190 200
VLFGQSIGGA NILDVIGRGD REGIRAVILD STFASYATIA NQMIPGSGYL
210 220 230 240 250
LDESYSGENY IASVSPIPLL LIHGKADHVI PWQHSEKLYS LAKEPKRLIL
260 270 280
IPDGEHIDAF SDRHGDVYRE QMVDFILSAL NPQN
Length:284
Mass (Da):31,516
Last modified:November 24, 2009 - v4
Checksum:iFB9ED6D7870A3FAA
GO

Sequence cautioni

The sequence BAA16428.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75587.2.
AP009048 Genomic DNA. Translation: BAA16428.1. Different initiation.
PIRiE65030.
RefSeqiNP_417029.4. NC_000913.3.
WP_001297705.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75587; AAC75587; b2534.
BAA16428; BAA16428; BAA16428.
GeneIDi945059.
KEGGiecj:JW2518.
eco:b2534.
PATRICi32120465. VBIEscCol129921_2635.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75587.2.
AP009048 Genomic DNA. Translation: BAA16428.1. Different initiation.
PIRiE65030.
RefSeqiNP_417029.4. NC_000913.3.
WP_001297705.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77538.
SMRiP77538. Positions 210-260.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260968. 19 interactions.
IntActiP77538. 5 interactions.
STRINGi511145.b2534.

Protein family/group databases

ESTHERiecoli-YfhR. ABHD13-BEM46.

Proteomic databases

PaxDbiP77538.
PRIDEiP77538.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75587; AAC75587; b2534.
BAA16428; BAA16428; BAA16428.
GeneIDi945059.
KEGGiecj:JW2518.
eco:b2534.
PATRICi32120465. VBIEscCol129921_2635.

Organism-specific databases

EchoBASEiEB3226.
EcoGeneiEG13453. yfhR.

Phylogenomic databases

eggNOGiENOG4107XM9. Bacteria.
COG1073. LUCA.
HOGENOMiHOG000007143.
InParanoidiP77538.
KOiK06889.
OrthoDBiEOG6677RW.
PhylomeDBiP77538.

Enzyme and pathway databases

BioCyciEcoCyc:G7328-MONOMER.
ECOL316407:JW2518-MONOMER.

Miscellaneous databases

PROiP77538.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR022742. Hydrolase_4.
[Graphical view]
PfamiPF12146. Hydrolase_4. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYFHR_ECOLI
AccessioniPrimary (citable) accession number: P77538
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: November 24, 2009
Last modified: May 11, 2016
This is version 120 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.