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Protein

Uncharacterized electron transport protein YkgF

Gene

ykgF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Miscellaneous

The E.coli ykgEFG operon is a clear homolog of the B.subtilis lutABC operon, however it is not able of restoring L-lactate utilization to the B.subtilis mutant for lutABC operon. Thus, ykgEFG operon may contribute to lactate catabolism in E.coli, but under conditions other than those tested, or alternatively, the ykgEFG operon may be responsible for the catabolism of a metabolite other than (but perhaps related to) lactate in E.coli.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi312Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi315Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi318Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi322Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi362Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi365Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi368Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi372Iron-sulfur 1 (4Fe-4S)By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6177-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized electron transport protein YkgF
Gene namesi
Name:ykgF
Ordered Locus Names:b0307, JW0300
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13583 ykgF

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001593021 – 475Uncharacterized electron transport protein YkgFAdd BLAST475

Proteomic databases

PaxDbiP77536
PRIDEiP77536

Interactioni

Protein-protein interaction databases

BioGridi4260872, 6 interactors
IntActiP77536, 26 interactors
STRINGi316385.ECDH10B_0295

Structurei

3D structure databases

ProteinModelPortaliP77536
SMRiP77536
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini303 – 3334Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd BLAST31
Domaini352 – 3814Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd BLAST30

Sequence similaritiesi

Belongs to the LutB/YkgF family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4107QR9 Bacteria
COG1139 LUCA
HOGENOMiHOG000262102
InParanoidiP77536
KOiK18929
OMAiHCPVYDK
PhylomeDBiP77536

Family and domain databases

Gene3Di3.40.50.10420, 1 hit
InterProiView protein in InterPro
IPR004452 4Fe-4S-bd
IPR024569 4Fe-4S-bd_C
IPR017896 4Fe4S_Fe-S-bd
IPR017900 4Fe4S_Fe_S_CS
IPR024185 FTHF_cligase-like_sf
IPR009051 Helical_ferredxn
IPR003741 LUD_dom
IPR037171 NagB/RpiA_transferase-like
PANTHERiPTHR32479:SF10 PTHR32479:SF10, 1 hit
PfamiView protein in Pfam
PF11870 DUF3390, 1 hit
PF13183 Fer4_8, 1 hit
PF02589 LUD_dom, 1 hit
SUPFAMiSSF100950 SSF100950, 2 hits
SSF46548 SSF46548, 1 hit
TIGRFAMsiTIGR00273 TIGR00273, 1 hit
PROSITEiView protein in PROSITE
PS00198 4FE4S_FER_1, 2 hits
PS51379 4FE4S_FER_2, 2 hits

Sequencei

Sequence statusi: Complete.

P77536-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIKTSNTDF KTRIRQQIED PIMRKAVANA QQRIGANRQK MVDELGHWEE
60 70 80 90 100
WRDRAAQIRD HVLSNLDAYL YQLSEKVTQN GGHVYFARTK EDATRYILQV
110 120 130 140 150
AQRKNARKVV KSKSMVTEEI GVNHVLQDAG IQVIETDLGE YILQLDQDPP
160 170 180 190 200
SHVVVPAIHK DRHQIRRVLH ERLGYEGPET PEAMTLFIRQ KIREDFLSAE
210 220 230 240 250
IGITGCNFAV AETGSVCLVT NEGNARMCTT LPKTHIAVMG MERIAPTFAE
260 270 280 290 300
VDVLITMLAR SAVGARLTGY NTWLTGPREA GHVDGPEEFH LVIVDNGRSE
310 320 330 340 350
VLASEFRDVL RCIRCGACMN TCPAYRHIGG HGYGSIYPGP IGAVISPLLG
360 370 380 390 400
GYKDFKDLPY ACSLCTACDN VCPVRIPLSK LILRHRRVMA EKGITAKAEQ
410 420 430 440 450
RAIKMFAYAN SHPGLWKVGM MAGAHAASWF INGGKTPLKF GAISDWMEAR
460 470
DLPEADGESF RSWFKKHQAQ EKKNG
Length:475
Mass (Da):53,052
Last modified:February 1, 1997 - v1
Checksum:i6B2429D387336F72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA Translation: AAB18034.1
U00096 Genomic DNA Translation: AAC73410.1
AP009048 Genomic DNA Translation: BAE76091.1
PIRiC64757
RefSeqiNP_414841.1, NC_000913.3
WP_000023927.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73410; AAC73410; b0307
BAE76091; BAE76091; BAE76091
GeneIDi944980
KEGGiecj:JW0300
eco:b0307
PATRICifig|1411691.4.peg.1970

Similar proteinsi

Entry informationi

Entry nameiYKGF_ECOLI
AccessioniPrimary (citable) accession number: P77536
Secondary accession number(s): Q2MCB5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: April 25, 2018
This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health