Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized ABC transporter ATP-binding protein YphE

Gene

yphE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Probably part of a binding-protein-dependent transport system YphDEF. Probably responsible for energy coupling to the transport system.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi43 – 50ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:YPHE-MONOMER

Protein family/group databases

TCDBi3.A.1.2.27 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized ABC transporter ATP-binding protein YphE
Gene namesi
Name:yphE
Ordered Locus Names:b2547, JW2531
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13466 yphE

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000931971 – 503Uncharacterized ABC transporter ATP-binding protein YphEAdd BLAST503

Proteomic databases

PaxDbiP77509
PRIDEiP77509

Interactioni

Protein-protein interaction databases

BioGridi4261315, 141 interactors
DIPiDIP-12830N
IntActiP77509, 7 interactors
STRINGi316385.ECDH10B_2714

Structurei

3D structure databases

ProteinModelPortaliP77509
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 249ABC transporter 1PROSITE-ProRule annotationAdd BLAST242
Domaini261 – 499ABC transporter 2PROSITE-ProRule annotationAdd BLAST239

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4108F37 Bacteria
COG1129 LUCA
InParanoidiP77509
KOiK02056
OMAiVHQEFSL
PhylomeDBiP77509

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequencei

Sequence statusi: Complete.

P77509-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTATEAVPV AKVVAGNKRY PGVVALDNVN FTLNKGEVRA LLGKNGAGKS
60 70 80 90 100
TLIRMLTGSE RPDSGDIWIG ETRLEGDEAT LTRRAAELGV RAVYQELSLV
110 120 130 140 150
EGLTVAENLC LGQWPRRNGM IDYLQMAQDA QRCLQALGVD VSPEQLVSTL
160 170 180 190 200
SPAQKQLVEI ARVMKGEPRV VILDEPTSSL ASAEVELVIS AVKKMSALGV
210 220 230 240 250
AVIYVSHRME EIRRIASCAT VMRDGQVAGD VMLENTSTHH IVSLMLGRDH
260 270 280 290 300
VDIAPVAPQE IVDQAVLEVR ALRHKPKLED ISFTLRRGEV LGIAGLLGAG
310 320 330 340 350
RSELLKAIVG LEEYEQGEIV INGEKITRPD YGDMLKRGIG YTPENRKEAG
360 370 380 390 400
IIPWLGVDEN TVLTNRQKIS ANGVLQWSTI RRLTEEVMQR MTVKAASSET
410 420 430 440 450
PIGTLSGGNQ QKVVIGRWVY AASQILLLDE PTRGVDIEAK QQIYRIVREL
460 470 480 490 500
AAEGKSVVFI SSEVEELPLV CDRILLLQHG TFSQEFHAPV NVDELMSAIL

SVH
Length:503
Mass (Da):55,016
Last modified:February 1, 1997 - v1
Checksum:i0D964916CE97A761
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75600.1
AP009048 Genomic DNA Translation: BAA16449.1
PIRiB65032
RefSeqiNP_417042.1, NC_000913.3
WP_000493470.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75600; AAC75600; b2547
BAA16449; BAA16449; BAA16449
GeneIDi948990
KEGGiecj:JW2531
eco:b2547
PATRICifig|1411691.4.peg.4187

Similar proteinsi

Entry informationi

Entry nameiYPHE_ECOLI
AccessioniPrimary (citable) accession number: P77509
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: April 25, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health