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Protein

Probable D,D-dipeptide transport system permease protein DdpC

Gene

ddpC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for the translocation of the substrate across the membrane.

GO - Biological processi

Keywordsi

Biological processPeptide transport, Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:YDDQ-MONOMER

Protein family/group databases

TCDBi3.A.1.5.38 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Probable D,D-dipeptide transport system permease protein DdpC
Gene namesi
Name:ddpC
Synonyms:yddQ
Ordered Locus Names:b1485, JW1480
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13788 ddpC

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 33CytoplasmicSequence analysisAdd BLAST33
Transmembranei34 – 54HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini55 – 96PeriplasmicSequence analysisAdd BLAST42
Transmembranei97 – 117HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini118 – 124CytoplasmicSequence analysis7
Transmembranei125 – 145HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei146 – 166HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini167 – 217CytoplasmicSequence analysisAdd BLAST51
Transmembranei218 – 238HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini239 – 260PeriplasmicSequence analysisAdd BLAST22
Transmembranei261 – 281HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini282 – 298CytoplasmicSequence analysisAdd BLAST17

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoliWiki
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602451 – 298Probable D,D-dipeptide transport system permease protein DdpCAdd BLAST298

Proteomic databases

PaxDbiP77463
PRIDEiP77463

Expressioni

Inductioni

Induced by RpoS in stationary phase.1 Publication

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (DdpD and DdpF), two transmembrane proteins (DdpB and DdpC) and a solute-binding protein (DdpA).Curated

Protein-protein interaction databases

BioGridi4260963, 273 interactors
IntActiP77463, 2 interactors
STRINGi316385.ECDH10B_1616

Structurei

3D structure databases

ProteinModelPortaliP77463
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini97 – 282ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST186

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C2T Bacteria
COG1173 LUCA
HOGENOMiHOG000171368
InParanoidiP77463
KOiK02034
OMAiTRPWLFW
PhylomeDBiP77463

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.10, 1 hit
InterProiView protein in InterPro
IPR000515 MetI-like
IPR035906 MetI-like_sf
IPR025966 OppC_N
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
PF12911 OppC_N, 1 hit
SUPFAMiSSF161098 SSF161098, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

P77463-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMLSEETSAV RPQKQTRFNG AKLVWMLKGS PLTVTSAVII VLMLLMMIFS
60 70 80 90 100
PWLATHDPNA IDLTARLLPP SAAHWFGTDE VGRDLFSRVL VGSQQSILAG
110 120 130 140 150
LVVVAIAGMI GSLLGCLSGV LGGRADAIIM RIMDIMLSIP SLVLTMALAA
160 170 180 190 200
ALGPSLFNAM LAIAIVRIPF YVRLARGQAL VVRQYTYVQA AKTFGASRWH
210 220 230 240 250
LINWHILRNS LPPLIVQASL DIGSAILMAA TLGFIGLGAQ QPSAEWGAMV
260 270 280 290
ANGRNYVLDQ WWYCAFPGAA ILLTAVGFNL FGDGIRDLLD PKAGGKQS
Length:298
Mass (Da):31,971
Last modified:February 1, 1997 - v1
Checksum:i721AB0225634AF6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74558.1
AP009048 Genomic DNA Translation: BAA15140.1
PIRiH64901
RefSeqiNP_416002.1, NC_000913.3
WP_000979626.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74558; AAC74558; b1485
BAA15140; BAA15140; BAA15140
GeneIDi946028
KEGGiecj:JW1480
eco:b1485
PATRICifig|1411691.4.peg.782

Similar proteinsi

Entry informationi

Entry nameiDDPC_ECOLI
AccessioniPrimary (citable) accession number: P77463
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health