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Protein

Hydrogenase-4 component F

Gene

hyfF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Possible component of hydrogenase 4.1 Publication

GO - Molecular functioni

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoliWiki

Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-143

Protein family/group databases

TCDBi3.D.1.9.1 the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrogenase-4 component F (EC:1.-.-.-)
Gene namesi
Name:hyfF1 Publication
Ordered Locus Names:b2486, JW2471
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14214 hyfF

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei34 – 54HelicalSequence analysisAdd BLAST21
Transmembranei75 – 95HelicalSequence analysisAdd BLAST21
Transmembranei122 – 142HelicalSequence analysisAdd BLAST21
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
Transmembranei256 – 276HelicalSequence analysisAdd BLAST21
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Transmembranei322 – 342HelicalSequence analysisAdd BLAST21
Transmembranei384 – 404HelicalSequence analysisAdd BLAST21
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21
Transmembranei457 – 477HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: EcoliWiki
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001182281 – 526Hydrogenase-4 component FAdd BLAST526

Proteomic databases

PaxDbiP77437
PRIDEiP77437

Interactioni

Protein-protein interaction databases

BioGridi4262930, 13 interactors
IntActiP77437, 1 interactor
STRINGi316385.ECDH10B_2652

Structurei

3D structure databases

ProteinModelPortaliP77437
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I subunit 5 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108JPZ Bacteria
COG0651 LUCA
HOGENOMiHOG000020533
InParanoidiP77437
KOiK12141
OMAiNILIIDW
PhylomeDBiP77437

Family and domain databases

InterProiView protein in InterPro
IPR001750 ND/Mrp_mem
IPR001516 Proton_antipo_N
PfamiView protein in Pfam
PF00361 Proton_antipo_M, 1 hit
PF00662 Proton_antipo_N, 1 hit

Sequencei

Sequence statusi: Complete.

P77437-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYSVMFALL LLTPLLFSLL CFACRKRRLS ATRTVTVLHS LGITLLLILA
60 70 80 90 100
LWVVQTAADA GEIFAAGLWL HIDGLGGLFL AILGVIGFLT GIYSIGYMRH
110 120 130 140 150
EVAHGELSPV TLCDYYGFFH LFLFTMLLVV TSNNLIVMWA AIEATTLSSA
160 170 180 190 200
FLVGIYGQRS SLEAAWKYII ICTVGVAFGL FGTVLVYANA ASVMPQAEMA
210 220 230 240 250
IFWSEVLKQS SLLDPTLMLL AFVFLLIGFG TKTGLFPMHA WLPDAHSEAP
260 270 280 290 300
SPVSALLSAV LLNCALLVLI RYYIIICQAI GSDFPNRLLL IFGMLSVAVA
310 320 330 340 350
AFFILVQRDI KRLLAYSSVE NMGLVAVELG IGGPLGIFAA LLHILNHSLA
360 370 380 390 400
KTLLFCGSGN VLLKYGTRDL NVVCGMLKIM PFTAVLFGGG ALALAGMPPF
410 420 430 440 450
NIFLSEFMTI TAGLARNHLL IIVLLLLLLT LVLAGLVRMA ARVLMAKPPQ
460 470 480 490 500
AVNRGDLGWL TTSPMVILLV MMLAMGTHIP QPVIRILAGA STIVLSGTHD
510 520
LPAQRSTWHD FLPSGTASVS EKHSER
Length:526
Mass (Da):56,767
Last modified:February 1, 1997 - v1
Checksum:i229068F616880775
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63654 Genomic DNA Translation: AAB88568.1
U00096 Genomic DNA Translation: AAC75539.1
AP009048 Genomic DNA Translation: BAA16374.1
PIRiE65024
RefSeqiNP_416981.1, NC_000913.3
WP_000122577.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75539; AAC75539; b2486
BAA16374; BAA16374; BAA16374
GeneIDi946962
KEGGiecj:JW2471
eco:b2486
PATRICifig|1411691.4.peg.4253

Similar proteinsi

Entry informationi

Entry nameiHYFF_ECOLI
AccessioniPrimary (citable) accession number: P77437
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health