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Protein

Hydrogenase-4 component D

Gene

hyfD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Possible component of hydrogenase 4.1 Publication

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-141

Protein family/group databases

TCDBi3.D.1.9.1 the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrogenase-4 component D (EC:1.-.-.-)
Gene namesi
Name:hyfD1 Publication
Ordered Locus Names:b2484, JW2469
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14212 hyfD

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei3 – 23HelicalSequence analysisAdd BLAST21
Transmembranei30 – 50HelicalSequence analysisAdd BLAST21
Transmembranei55 – 75HelicalSequence analysisAdd BLAST21
Transmembranei80 – 100HelicalSequence analysisAdd BLAST21
Transmembranei117 – 137HelicalSequence analysisAdd BLAST21
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Transmembranei208 – 228HelicalSequence analysisAdd BLAST21
Transmembranei238 – 258HelicalSequence analysisAdd BLAST21
Transmembranei270 – 290HelicalSequence analysisAdd BLAST21
Transmembranei300 – 320HelicalSequence analysisAdd BLAST21
Transmembranei330 – 350HelicalSequence analysisAdd BLAST21
Transmembranei369 – 389HelicalSequence analysisAdd BLAST21
Transmembranei390 – 410HelicalSequence analysisAdd BLAST21
Transmembranei411 – 431HelicalSequence analysisAdd BLAST21
Transmembranei458 – 478HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoliWiki
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001182271 – 479Hydrogenase-4 component DAdd BLAST479

Proteomic databases

PaxDbiP77416
PRIDEiP77416

Interactioni

Protein-protein interaction databases

BioGridi4259198, 19 interactors
STRINGi316385.ECDH10B_2650

Structurei

3D structure databases

ProteinModelPortaliP77416
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I subunit 5 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D65 Bacteria
COG1009 LUCA
HOGENOMiHOG000219587
InParanoidiP77416
KOiK12139
OMAiFWLVPAY
PhylomeDBiP77416

Family and domain databases

InterProiView protein in InterPro
IPR001750 ND/Mrp_mem
IPR001516 Proton_antipo_N
PfamiView protein in Pfam
PF00361 Proton_antipo_M, 1 hit
PF00662 Proton_antipo_N, 1 hit

Sequencei

Sequence statusi: Complete.

P77416-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENLALTTLL LPFIGALVVS FSPQRRAAEW GVLFAALTTL CMLSLISAFY
60 70 80 90 100
QADKVAVTLT LVNVGDVALF GLVIDRVSTL ILFVVVFLGL LVTIYSTGYL
110 120 130 140 150
TDKNREHPHN GTNRYYAFLL VFIGAMAGLV LSSTLLGQLL FFEITGGCSW
160 170 180 190 200
ALISYYQSDK AQRSALKALL ITHIGSLGLY LAAATLFLQT GTFALSAMSE
210 220 230 240 250
LHGDARYLVY GGILFAAWGK SAQLPMQAWL PDAMEAPTPI SAYLHAASMV
260 270 280 290 300
KVGVYIFARA IIDGGNIPHV IGGVGMVMAL VTILYGFLMY LPQQDMKRLL
310 320 330 340 350
AWSTITQLGW MFFGLSLSIF GSRLALEGSI AYIVNHAFAK SLFFLVAGAL
360 370 380 390 400
SYSCGTRLLP RLRGVLHTLP LPGVGFCVAA LAITGVPPFN GFFSKFPLFA
410 420 430 440 450
AGFALSVEYW ILLPAMILLM IESVASFAWF IRWFGRVVPG KPSEAVADAA
460 470
PLPGSMRLVL IVLIVMSLIS SVIAATWLQ
Length:479
Mass (Da):51,755
Last modified:February 1, 1997 - v1
Checksum:i61777107CC9100F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63654 Genomic DNA Translation: AAB88566.1
U00096 Genomic DNA Translation: AAC75537.1
AP009048 Genomic DNA Translation: BAA16372.1
PIRiC65024
RefSeqiNP_416979.1, NC_000913.3
WP_000429104.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75537; AAC75537; b2484
BAA16372; BAA16372; BAA16372
GeneIDi947290
KEGGiecj:JW2469
eco:b2484
PATRICifig|1411691.4.peg.4255

Similar proteinsi

Entry informationi

Entry nameiHYFD_ECOLI
AccessioniPrimary (citable) accession number: P77416
Secondary accession number(s): P76973
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health