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Protein

Putative colanic acid biosynthesis glycosyl transferase WcaA

Gene

wcaA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Pathwayi: slime polysaccharide biosynthesis

This protein is involved in the pathway slime polysaccharide biosynthesis, which is part of Slime biogenesis.
View all proteins of this organism that are known to be involved in the pathway slime polysaccharide biosynthesis and in Slime biogenesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:G7104-MONOMER.
ECOL316407:JW2044-MONOMER.
UniPathwayiUPA00936.

Protein family/group databases

CAZyiGT2. Glycosyltransferase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative colanic acid biosynthesis glycosyl transferase WcaA
Gene namesi
Name:wcaA
Ordered Locus Names:b2059, JW2044
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13569. wcaA.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 279279Putative colanic acid biosynthesis glycosyl transferase WcaAPRO_0000065953Add
BLAST

Proteomic databases

PaxDbiP77414.

Interactioni

Protein-protein interaction databases

BioGridi4259687. 312 interactions.
IntActiP77414. 8 interactions.
STRINGi511145.b2059.

Structurei

3D structure databases

ProteinModelPortaliP77414.
SMRiP77414. Positions 1-188.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To R.meliloti ExoO.Curated

Phylogenomic databases

eggNOGiENOG41090RK. Bacteria.
COG0463. LUCA.
HOGENOMiHOG000121977.
InParanoidiP77414.
OMAiTHNAINS.
OrthoDBiEOG63C0TJ.
PhylomeDBiP77414.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR024009. Colanic_acid_synth_WcaA.
IPR001173. Glyco_trans_2-like.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00535. Glycos_transf_2. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR04017. WcaA. 1 hit.

Sequencei

Sequence statusi: Complete.

P77414-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNNPLISIY MPTWNRQQLA IRAIKSVLRQ DYSNWEMIIV DDCSTSWEQL
60 70 80 90 100
QQYVTALNDP RITYIHNDIN SGACAVRNQA IMLAQGEYIT GIDDDDEWTP
110 120 130 140 150
NRLSVFLAHK QQLVTHAFLY ANDYVCQGEV YSQPASLPLY PKSPYSRRLF
160 170 180 190 200
YKRNIIGNQV FTWAWRFKEC LFDTELKAAQ DYDIFLRMVV EYGEPWKVEE
210 220 230 240 250
ATQILHINHG EMQITSSPKK FSGYFHFYRK HKDKFDRASK KYQLFTLYQI
260 270
RNKRMTWRTL LTLLSVRNGK RLADGIRGR
Length:279
Mass (Da):33,035
Last modified:February 1, 1997 - v1
Checksum:i75F74D30026E327A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA. Translation: AAC77836.1.
U00096 Genomic DNA. Translation: AAC75120.1.
AP009048 Genomic DNA. Translation: BAA15912.1.
PIRiB64972.
RefSeqiNP_416563.1. NC_000913.3.
WP_000794699.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75120; AAC75120; b2059.
BAA15912; BAA15912; BAA15912.
GeneIDi946570.
KEGGiecj:JW2044.
eco:b2059.
PATRICi32119451. VBIEscCol129921_2136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38473 Genomic DNA. Translation: AAC77836.1.
U00096 Genomic DNA. Translation: AAC75120.1.
AP009048 Genomic DNA. Translation: BAA15912.1.
PIRiB64972.
RefSeqiNP_416563.1. NC_000913.3.
WP_000794699.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77414.
SMRiP77414. Positions 1-188.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259687. 312 interactions.
IntActiP77414. 8 interactions.
STRINGi511145.b2059.

Protein family/group databases

CAZyiGT2. Glycosyltransferase Family 2.

Proteomic databases

PaxDbiP77414.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75120; AAC75120; b2059.
BAA15912; BAA15912; BAA15912.
GeneIDi946570.
KEGGiecj:JW2044.
eco:b2059.
PATRICi32119451. VBIEscCol129921_2136.

Organism-specific databases

EchoBASEiEB3339.
EcoGeneiEG13569. wcaA.

Phylogenomic databases

eggNOGiENOG41090RK. Bacteria.
COG0463. LUCA.
HOGENOMiHOG000121977.
InParanoidiP77414.
OMAiTHNAINS.
OrthoDBiEOG63C0TJ.
PhylomeDBiP77414.

Enzyme and pathway databases

UniPathwayiUPA00936.
BioCyciEcoCyc:G7104-MONOMER.
ECOL316407:JW2044-MONOMER.

Miscellaneous databases

PROiP77414.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR024009. Colanic_acid_synth_WcaA.
IPR001173. Glyco_trans_2-like.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00535. Glycos_transf_2. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR04017. WcaA. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid."
    Stevenson G., Andrianopoulos K., Hobbs M., Reeves P.R.
    J. Bacteriol. 178:4885-4893(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiWCAA_ECOLI
AccessioniPrimary (citable) accession number: P77414
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: January 20, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.