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Protein

Protein PhsC homolog

Gene

ydhU

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BioCyciEcoCyc:G6898-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PhsC homolog
Gene namesi
Name:ydhU
Ordered Locus Names:b1670, JW1660
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13955. ydhU.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Transmembranei81 – 101HelicalSequence analysisAdd BLAST21
Transmembranei108 – 128HelicalSequence analysisAdd BLAST21
Transmembranei182 – 202HelicalSequence analysisAdd BLAST21
Transmembranei224 – 244HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000584071 – 261Protein PhsC homologAdd BLAST261

Proteomic databases

PaxDbiP77409.
PRIDEiP77409.

Expressioni

Inductioni

Up-regulated by the oxygen-responsive transcription factor FNR under anaerobic conditions. Repressed in the presence of nitrate or nitrite via the two-component systems NarXL and NarPQ, respectively.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4262230. 6 interactors.
DIPiDIP-11740N.
IntActiP77409. 3 interactors.
MINTiMINT-1292289.
STRINGi316385.ECDH10B_1804.

Structurei

3D structure databases

ProteinModelPortaliP77409.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108NWD. Bacteria.
COG4117. LUCA.
HOGENOMiHOG000004863.
InParanoidiP77409.
KOiK08354.
PhylomeDBiP77409.

Family and domain databases

InterProiView protein in InterPro
IPR011577. Cyt_b561_bac/Ni-Hgenase.
IPR016174. Di-haem_cyt_TM.
PfamiView protein in Pfam
PF01292. Ni_hydr_CYTB. 1 hit.
SUPFAMiSSF81342. SSF81342. 1 hit.

Sequencei

Sequence statusi: Complete.

P77409-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPSQHAEQF QSQLANYVPQ FTPEFWPVWL IIAGVLLVGM WLVLGLHALL
60 70 80 90 100
RARGVKKSAT DHGEKIYLYS KAVRLWHWSN ALLFVLLLAS GLINHFAMVG
110 120 130 140 150
ATAVKSLVAV HEVCGFLLLA CWLGFVLINA VGDNGHHYRI RRQGWLERAA
160 170 180 190 200
KQTRFYLFGI MQGEEHPFPA TTQSKFNPLQ QVAYVGVMYG LLPLLLLTGL
210 220 230 240 250
LCLYPQAVGD VFPGVRYWLL QTHFALAFIS LFFIFGHLYL CTTGRTPHET
260
FKSMVDGYHR H
Length:261
Mass (Da):29,583
Last modified:February 1, 1997 - v1
Checksum:i65CF1A45691A0AF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U68703 Genomic DNA. Translation: AAB47946.1.
U00096 Genomic DNA. Translation: AAC74740.1.
AP009048 Genomic DNA. Translation: BAA15442.1.
PIRiF64924.
RefSeqiNP_416185.1. NC_000913.3.
WP_001069979.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74740; AAC74740; b1670.
BAA15442; BAA15442; BAA15442.
GeneIDi945608.
KEGGiecj:JW1660.
eco:b1670.
PATRICifig|1411691.4.peg.589.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiPHSC_ECOLI
AccessioniPrimary (citable) accession number: P77409
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: July 5, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene