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P77377 (WZXC_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lipopolysaccharide biosynthesis protein WzxC
Gene names
Name:wzxC
Synonyms:wzx
Ordered Locus Names:b2046, JW2031
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 492492Lipopolysaccharide biosynthesis protein WzxC
PRO_0000166453

Regions

Topological domain1 – 1212Cytoplasmic Potential
Transmembrane13 – 3321Helical; Potential
Topological domain34 – 429Periplasmic Potential
Transmembrane43 – 6321Helical; Potential
Topological domain64 – 8118Cytoplasmic Potential
Transmembrane82 – 10221Helical; Potential
Topological domain103 – 1042Periplasmic Potential
Transmembrane105 – 12521Helical; Potential
Topological domain126 – 15732Cytoplasmic Potential
Transmembrane158 – 17821Helical; Potential
Topological domain179 – 23658Periplasmic Potential
Transmembrane237 – 25721Helical; Potential
Topological domain258 – 28831Cytoplasmic Potential
Transmembrane289 – 30921Helical; Potential
Topological domain310 – 32213Periplasmic Potential
Transmembrane323 – 34321Helical; Potential
Topological domain344 – 36421Cytoplasmic Potential
Transmembrane365 – 38521Helical; Potential
Topological domain3861Periplasmic Potential
Transmembrane387 – 40721Helical; Potential
Topological domain408 – 41710Cytoplasmic Potential
Transmembrane418 – 43821Helical; Potential
Topological domain439 – 4457Periplasmic Potential
Transmembrane446 – 46621Helical; Potential
Topological domain467 – 49226Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P77377 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 893E505759363A80

FASTA49253,693
        10         20         30         40         50         60 
MSLREKTISG AKWSAIATVI IIGLGLVQMT VLARIIDNHQ FGLLTVSLVI IALADTLSDF 

        70         80         90        100        110        120 
GIANSIIQRK EISHLELTTL YWLNVGLGIV VCVAVFLLSD LIGDVLNNPD LAPLIKTLSL 

       130        140        150        160        170        180 
AFVVIPHGQQ FRALMQKELE FNKIGMIETS AVLAGFTCTV VSAHFWPLAM TAILGYLVNS 

       190        200        210        220        230        240 
AVRTLLFGYF GRKIYRPGLH FSLASVAPNL RFGAWLTADS IINYLNTNLS TLVLARILGA 

       250        260        270        280        290        300 
GVAGGYNLAY NVAVVPPMKL NPIITRVLFP AFAKIQDDTE KLRVNFYKLL SVVGIINFPA 

       310        320        330        340        350        360 
LLGLMVVSNN FVPLVFGEKW NSIIPVLQLL CVVGLLRSVG NPIGSLLMAK ARVDISFKFN 

       370        380        390        400        410        420 
VFKTFLFIPA IVIGGQMAGA IGVTLGFLLV QIINTILSYF VMIKPVLGSS YRQYILSLWL 

       430        440        450        460        470        480 
PFYLSLPTLV VSYALGIVLK GQLALGMLLA VQIATGVLAF VVMIVLSRHP LVVEVKRQFC 

       490 
RSEKMKMLLR AG 

« Hide

References

« Hide 'large scale' references
[1]"Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid."
Stevenson G., Andrianopoulos K., Hobbs M., Reeves P.R.
J. Bacteriol. 178:4885-4893(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: K12.
[2]"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map."
Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. expand/collapse author list , Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:379-392(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: K12 / MG1655 / ATCC 47076.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U38473 Genomic DNA. Translation: AAC77849.1.
U00096 Genomic DNA. Translation: AAC75107.1.
AP009048 Genomic DNA. Translation: BAA15899.1.
PIRE64970.
RefSeqNP_416550.1. NC_000913.3.
YP_490288.1. NC_007779.1.

3D structure databases

ProteinModelPortalP77377.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-11136N.
IntActP77377. 1 interaction.
MINTMINT-1312635.
STRING511145.b2046.

Protein family/group databases

TCDB2.A.66.2.7. the multidrug/oligosaccharidyl-lipid/polysaccharide (mop) flippase superfamily.

Proteomic databases

PaxDbP77377.
PRIDEP77377.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC75107; AAC75107; b2046.
BAA15899; BAA15899; BAA15899.
GeneID12934319.
946581.
KEGGecj:Y75_p2009.
eco:b2046.
PATRIC32119425. VBIEscCol129921_2123.

Organism-specific databases

EchoBASEEB3346.
EcoGeneEG13576. wzxC.

Phylogenomic databases

eggNOGCOG2244.
HOGENOMHOG000121955.
KOK16695.
OMAVEMKRQF.
OrthoDBEOG6WHNQ7.
PhylomeDBP77377.

Enzyme and pathway databases

BioCycEcoCyc:G7097-MONOMER.
ECOL316407:JW2031-MONOMER.
UniPathwayUPA00030.

Gene expression databases

GenevestigatorP77377.

Family and domain databases

InterProIPR002797. Polysacc_synth.
[Graphical view]
PfamPF01943. Polysacc_synt. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP77377.

Entry information

Entry nameWZXC_ECOLI
AccessionPrimary (citable) accession number: P77377
Secondary accession number(s): O08001, O08002
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: May 14, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene