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Protein

Uncharacterized ferredoxin-like protein YdhX

Gene

ydhX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi46Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi49Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi52Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi56Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi92Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi95Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi100Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi104Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi124Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi127Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi130Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi134Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi151Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi154Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi167Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi171Iron-sulfur 1 (4Fe-4S)By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6899-MONOMER.
ECOL316407:JW5271-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized ferredoxin-like protein YdhX
Gene namesi
Name:ydhX
Ordered Locus Names:b1671, JW5271
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13958. ydhX.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GO_Central
  • outer membrane-bounded periplasmic space Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Tat-type signalSequence analysisAdd BLAST27
ChainiPRO_000015929528 – 222Uncharacterized ferredoxin-like protein YdhXAdd BLAST195

Post-translational modificationi

Exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. Can also be exported by the Sec system.

Proteomic databases

PaxDbiP77375.
PRIDEiP77375.

Expressioni

Inductioni

Up-regulated by the oxygen-responsive transcription factor FNR under anaerobic conditions. Repressed in the presence of nitrate or nitrite via the two-component systems NarXL and NarPQ, respectively.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4263343. 13 interactors.
DIPiDIP-48159N.
STRINGi511145.b1671.

Structurei

3D structure databases

ProteinModelPortaliP77375.
SMRiP77375.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 674Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd BLAST31
Domaini83 – 1144Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd BLAST32
Domaini115 – 1444Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd BLAST30

Sequence similaritiesi

Contains 3 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiENOG4108393. Bacteria.
COG0437. LUCA.
HOGENOMiHOG000163388.
InParanoidiP77375.
PhylomeDBiP77375.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P77375-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFTRRKFVL GMGTVIFFTG SASSLLANTR QEKEVRYAMI HDESRCNGCN
60 70 80 90 100
ICARACRKTN HVPAQGSRLS IAHIPVTDND NETQYHFFRQ SCQHCEDAPC
110 120 130 140 150
IDVCPTGASW RDEQGIVRVE KSQCIGCSYC IGACPYQVRY LNPVTKVADK
160 170 180 190 200
CDFCAESRLA KGFPPICVSA CPEHALIFGR EDSPEIQAWL QQNKYYQYQL
210 220
PGAGKPHLYR RFGQHLIKKE NV
Length:222
Mass (Da):25,093
Last modified:November 24, 2009 - v4
Checksum:i95FE1FC3687E6E0D
GO

Sequence cautioni

The sequence AAB47947 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74741.4.
U68703 Genomic DNA. Translation: AAB47947.1. Different initiation.
AP009048 Genomic DNA. Translation: BAA15443.2.
PIRiG64924.
RefSeqiNP_416186.4. NC_000913.3.
WP_001310861.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74741; AAC74741; b1671.
BAA15443; BAA15443; BAA15443.
GeneIDi947308.
KEGGiecj:JW5271.
eco:b1671.
PATRICi32118648. VBIEscCol129921_1742.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74741.4.
U68703 Genomic DNA. Translation: AAB47947.1. Different initiation.
AP009048 Genomic DNA. Translation: BAA15443.2.
PIRiG64924.
RefSeqiNP_416186.4. NC_000913.3.
WP_001310861.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77375.
SMRiP77375.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263343. 13 interactors.
DIPiDIP-48159N.
STRINGi511145.b1671.

Proteomic databases

PaxDbiP77375.
PRIDEiP77375.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74741; AAC74741; b1671.
BAA15443; BAA15443; BAA15443.
GeneIDi947308.
KEGGiecj:JW5271.
eco:b1671.
PATRICi32118648. VBIEscCol129921_1742.

Organism-specific databases

EchoBASEiEB3716.
EcoGeneiEG13958. ydhX.

Phylogenomic databases

eggNOGiENOG4108393. Bacteria.
COG0437. LUCA.
HOGENOMiHOG000163388.
InParanoidiP77375.
PhylomeDBiP77375.

Enzyme and pathway databases

BioCyciEcoCyc:G6899-MONOMER.
ECOL316407:JW5271-MONOMER.

Miscellaneous databases

PROiP77375.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYDHX_ECOLI
AccessioniPrimary (citable) accession number: P77375
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: November 24, 2009
Last modified: November 2, 2016
This is version 126 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.