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Protein

Uncharacterized ferredoxin-like protein YdhX

Gene

ydhX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi46 – 461Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi49 – 491Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi52 – 521Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi56 – 561Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi92 – 921Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi95 – 951Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi100 – 1001Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi104 – 1041Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi124 – 1241Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi127 – 1271Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi130 – 1301Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi134 – 1341Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi151 – 1511Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi154 – 1541Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi167 – 1671Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi171 – 1711Iron-sulfur 1 (4Fe-4S)By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6899-MONOMER.
ECOL316407:JW5271-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized ferredoxin-like protein YdhX
Gene namesi
Name:ydhX
Ordered Locus Names:b1671, JW5271
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13958. ydhX.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GO_Central
  • outer membrane-bounded periplasmic space Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Tat-type signalSequence analysisAdd
BLAST
Chaini28 – 222195Uncharacterized ferredoxin-like protein YdhXPRO_0000159295Add
BLAST

Post-translational modificationi

Exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. Can also be exported by the Sec system.

Proteomic databases

PaxDbiP77375.
PRIDEiP77375.

Expressioni

Inductioni

Up-regulated by the oxygen-responsive transcription factor FNR under anaerobic conditions. Repressed in the presence of nitrate or nitrite via the two-component systems NarXL and NarPQ, respectively.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4263343. 13 interactions.
DIPiDIP-48159N.
STRINGi511145.b1671.

Structurei

3D structure databases

ProteinModelPortaliP77375.
SMRiP77375. Positions 36-185.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini37 – 67314Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd
BLAST
Domaini83 – 114324Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd
BLAST
Domaini115 – 144304Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 3 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiENOG4108393. Bacteria.
COG0437. LUCA.
HOGENOMiHOG000163388.
InParanoidiP77375.
PhylomeDBiP77375.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P77375-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFTRRKFVL GMGTVIFFTG SASSLLANTR QEKEVRYAMI HDESRCNGCN
60 70 80 90 100
ICARACRKTN HVPAQGSRLS IAHIPVTDND NETQYHFFRQ SCQHCEDAPC
110 120 130 140 150
IDVCPTGASW RDEQGIVRVE KSQCIGCSYC IGACPYQVRY LNPVTKVADK
160 170 180 190 200
CDFCAESRLA KGFPPICVSA CPEHALIFGR EDSPEIQAWL QQNKYYQYQL
210 220
PGAGKPHLYR RFGQHLIKKE NV
Length:222
Mass (Da):25,093
Last modified:November 24, 2009 - v4
Checksum:i95FE1FC3687E6E0D
GO

Sequence cautioni

The sequence AAB47947 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74741.4.
U68703 Genomic DNA. Translation: AAB47947.1. Different initiation.
AP009048 Genomic DNA. Translation: BAA15443.2.
PIRiG64924.
RefSeqiNP_416186.4. NC_000913.3.
WP_001310861.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74741; AAC74741; b1671.
BAA15443; BAA15443; BAA15443.
GeneIDi947308.
KEGGiecj:JW5271.
eco:b1671.
PATRICi32118648. VBIEscCol129921_1742.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74741.4.
U68703 Genomic DNA. Translation: AAB47947.1. Different initiation.
AP009048 Genomic DNA. Translation: BAA15443.2.
PIRiG64924.
RefSeqiNP_416186.4. NC_000913.3.
WP_001310861.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77375.
SMRiP77375. Positions 36-185.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263343. 13 interactions.
DIPiDIP-48159N.
STRINGi511145.b1671.

Proteomic databases

PaxDbiP77375.
PRIDEiP77375.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74741; AAC74741; b1671.
BAA15443; BAA15443; BAA15443.
GeneIDi947308.
KEGGiecj:JW5271.
eco:b1671.
PATRICi32118648. VBIEscCol129921_1742.

Organism-specific databases

EchoBASEiEB3716.
EcoGeneiEG13958. ydhX.

Phylogenomic databases

eggNOGiENOG4108393. Bacteria.
COG0437. LUCA.
HOGENOMiHOG000163388.
InParanoidiP77375.
PhylomeDBiP77375.

Enzyme and pathway databases

BioCyciEcoCyc:G6899-MONOMER.
ECOL316407:JW5271-MONOMER.

Miscellaneous databases

PROiP77375.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYDHX_ECOLI
AccessioniPrimary (citable) accession number: P77375
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: November 24, 2009
Last modified: September 7, 2016
This is version 124 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.