Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized zinc-type alcohol dehydrogenase-like protein YphC

Gene

yphC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi40 – 401Zinc 1; catalyticBy similarity
Metal bindingi70 – 701Zinc 1; catalyticBy similarity
Metal bindingi100 – 1001Zinc 2By similarity
Metal bindingi103 – 1031Zinc 2By similarity
Metal bindingi106 – 1061Zinc 2By similarity
Metal bindingi114 – 1141Zinc 2By similarity
Metal bindingi158 – 1581Zinc 1; catalyticBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciEcoCyc:YPHC-MONOMER.
ECOL316407:JW5842-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized zinc-type alcohol dehydrogenase-like protein YphC (EC:1.-.-.-)
Gene namesi
Name:yphC
Ordered Locus Names:b2545, JW5842
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13464. yphC.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 353353Uncharacterized zinc-type alcohol dehydrogenase-like protein YphCPRO_0000160899Add
BLAST

Proteomic databases

PaxDbiP77360.

Interactioni

Protein-protein interaction databases

BioGridi4261318. 8 interactions.
STRINGi511145.b2545.

Structurei

3D structure databases

ProteinModelPortaliP77360.
SMRiP77360. Positions 1-349.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CPQ. Bacteria.
COG1063. LUCA.
HOGENOMiHOG000294691.
InParanoidiP77360.
OMAiECHAGHQ.
PhylomeDBiP77360.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 1 hit.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 2 hits.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00059. ADH_ZINC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77360-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTMLAAYLP GNSTVDLREV AVPTPGINQV LIKMKSSGIC GSDVHYIYHQ
60 70 80 90 100
HRATAAAPDK PLYQGFINGH EPCGQIVAMG QGCRHFKEGD RVLVYHISGC
110 120 130 140 150
GFCPNCRRGF PISCTGEGKA AYGWQRDGGH AEYLLAEEKD LILLPDALSY
160 170 180 190 200
EDGAFISCGV GTAYEGILRG EVSGSDNVLV VGLGPVGMMA MMLAKGRGAK
210 220 230 240 250
RIIGVDMLPE RLAMAKQLGV MDHGYLATTE GLPQIIAELT HGGADVALDC
260 270 280 290 300
SGNAAGRLLA LQSTADWGRV VYIGETGKVE FEVSADLMHH QRRIIGSWVT
310 320 330 340 350
SLFHMEKCAH DLTDWKLWPR NAITHRFSLE QAGDAYALMA SGKCGKVVIN

FPD
Length:353
Mass (Da):38,051
Last modified:May 30, 2000 - v2
Checksum:i71973759FC7334DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75598.2.
AP009048 Genomic DNA. Translation: BAA16447.2.
PIRiH65031.
RefSeqiNP_417040.2. NC_000913.3.
WP_001393448.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75598; AAC75598; b2545.
BAA16447; BAA16447; BAA16447.
GeneIDi947019.
KEGGiecj:JW5842.
eco:b2545.
PATRICi32120487. VBIEscCol129921_2646.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75598.2.
AP009048 Genomic DNA. Translation: BAA16447.2.
PIRiH65031.
RefSeqiNP_417040.2. NC_000913.3.
WP_001393448.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77360.
SMRiP77360. Positions 1-349.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261318. 8 interactions.
STRINGi511145.b2545.

Proteomic databases

PaxDbiP77360.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75598; AAC75598; b2545.
BAA16447; BAA16447; BAA16447.
GeneIDi947019.
KEGGiecj:JW5842.
eco:b2545.
PATRICi32120487. VBIEscCol129921_2646.

Organism-specific databases

EchoBASEiEB3237.
EcoGeneiEG13464. yphC.

Phylogenomic databases

eggNOGiENOG4105CPQ. Bacteria.
COG1063. LUCA.
HOGENOMiHOG000294691.
InParanoidiP77360.
OMAiECHAGHQ.
PhylomeDBiP77360.

Enzyme and pathway databases

BioCyciEcoCyc:YPHC-MONOMER.
ECOL316407:JW5842-MONOMER.

Miscellaneous databases

PROiP77360.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 1 hit.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 2 hits.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00059. ADH_ZINC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYPHC_ECOLI
AccessioniPrimary (citable) accession number: P77360
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: May 30, 2000
Last modified: September 7, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.