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Protein

Uncharacterized zinc-type alcohol dehydrogenase-like protein YphC

Gene

yphC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi40Zinc 1; catalyticBy similarity1
Metal bindingi70Zinc 1; catalyticBy similarity1
Metal bindingi100Zinc 2By similarity1
Metal bindingi103Zinc 2By similarity1
Metal bindingi106Zinc 2By similarity1
Metal bindingi114Zinc 2By similarity1
Metal bindingi158Zinc 1; catalyticBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciEcoCyc:YPHC-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized zinc-type alcohol dehydrogenase-like protein YphC (EC:1.-.-.-)
Gene namesi
Name:yphC
Ordered Locus Names:b2545, JW5842
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13464 yphC

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001608991 – 353Uncharacterized zinc-type alcohol dehydrogenase-like protein YphCAdd BLAST353

Proteomic databases

PaxDbiP77360
PRIDEiP77360

Interactioni

Protein-protein interaction databases

BioGridi4261318, 8 interactors
STRINGi316385.ECDH10B_2712

Structurei

3D structure databases

ProteinModelPortaliP77360
SMRiP77360
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CPQ Bacteria
COG1063 LUCA
HOGENOMiHOG000294691
InParanoidiP77360
OMAiCHSDIAV
PhylomeDBiP77360

Family and domain databases

InterProiView protein in InterPro
IPR013149 ADH_C
IPR013154 ADH_N
IPR002328 ADH_Zn_CS
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
IPR020843 PKS_ER
PfamiView protein in Pfam
PF08240 ADH_N, 1 hit
PF00107 ADH_zinc_N, 1 hit
SMARTiView protein in SMART
SM00829 PKS_ER, 1 hit
SUPFAMiSSF50129 SSF50129, 2 hits
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00059 ADH_ZINC, 1 hit

Sequencei

Sequence statusi: Complete.

P77360-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTMLAAYLP GNSTVDLREV AVPTPGINQV LIKMKSSGIC GSDVHYIYHQ
60 70 80 90 100
HRATAAAPDK PLYQGFINGH EPCGQIVAMG QGCRHFKEGD RVLVYHISGC
110 120 130 140 150
GFCPNCRRGF PISCTGEGKA AYGWQRDGGH AEYLLAEEKD LILLPDALSY
160 170 180 190 200
EDGAFISCGV GTAYEGILRG EVSGSDNVLV VGLGPVGMMA MMLAKGRGAK
210 220 230 240 250
RIIGVDMLPE RLAMAKQLGV MDHGYLATTE GLPQIIAELT HGGADVALDC
260 270 280 290 300
SGNAAGRLLA LQSTADWGRV VYIGETGKVE FEVSADLMHH QRRIIGSWVT
310 320 330 340 350
SLFHMEKCAH DLTDWKLWPR NAITHRFSLE QAGDAYALMA SGKCGKVVIN

FPD
Length:353
Mass (Da):38,051
Last modified:May 30, 2000 - v2
Checksum:i71973759FC7334DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75598.2
AP009048 Genomic DNA Translation: BAA16447.2
PIRiH65031
RefSeqiNP_417040.2, NC_000913.3
WP_001393448.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75598; AAC75598; b2545
BAA16447; BAA16447; BAA16447
GeneIDi947019
KEGGiecj:JW5842
eco:b2545
PATRICifig|1411691.4.peg.4189

Similar proteinsi

Entry informationi

Entry nameiYPHC_ECOLI
AccessioniPrimary (citable) accession number: P77360
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: May 30, 2000
Last modified: March 28, 2018
This is version 128 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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