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Protein

Putative purine permease YbbY

Gene

ybbY

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:G6282-MONOMER.

Protein family/group databases

TCDBi2.A.40.5.1. the nucleobase/ascorbate transporter (nat) or nucleobase:cation symporter-2 (ncs2) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative purine permease YbbY
Gene namesi
Name:ybbY
Synonyms:glxB4
Ordered Locus Names:b0513, JW0501
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13620. ybbY.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 17PeriplasmicSequence analysisAdd BLAST17
Transmembranei18 – 38HelicalSequence analysisAdd BLAST21
Topological domaini39 – 42CytoplasmicSequence analysis4
Transmembranei43 – 63HelicalSequence analysisAdd BLAST21
Topological domaini64 – 68PeriplasmicSequence analysis5
Transmembranei69 – 89HelicalSequence analysisAdd BLAST21
Topological domaini90 – 102CytoplasmicSequence analysisAdd BLAST13
Transmembranei103 – 123HelicalSequence analysisAdd BLAST21
Topological domaini124 – 130PeriplasmicSequence analysis7
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21
Topological domaini152 – 169CytoplasmicSequence analysisAdd BLAST18
Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
Topological domaini191 – 196PeriplasmicSequence analysis6
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Topological domaini218 – 230CytoplasmicSequence analysisAdd BLAST13
Transmembranei231 – 251HelicalSequence analysisAdd BLAST21
Topological domaini252 – 288PeriplasmicSequence analysisAdd BLAST37
Transmembranei289 – 309HelicalSequence analysisAdd BLAST21
Topological domaini310 – 319CytoplasmicSequence analysis10
Transmembranei320 – 340HelicalSequence analysisAdd BLAST21
Topological domaini341 – 345PeriplasmicSequence analysis5
Transmembranei346 – 366HelicalSequence analysisAdd BLAST21
Topological domaini367 – 379CytoplasmicSequence analysisAdd BLAST13
Transmembranei380 – 400HelicalSequence analysisAdd BLAST21
Topological domaini401 – 407PeriplasmicSequence analysis7
Transmembranei408 – 428HelicalSequence analysisAdd BLAST21
Topological domaini429 – 433CytoplasmicSequence analysis5

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001659631 – 433Putative purine permease YbbYAdd BLAST433

Proteomic databases

PaxDbiP77328.
PRIDEiP77328.

Expressioni

Inductioni

By glyoxylate.

Interactioni

Protein-protein interaction databases

BioGridi4259872. 208 interactors.
STRINGi316385.ECDH10B_0469.

Structurei

3D structure databases

ProteinModelPortaliP77328.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DTE. Bacteria.
COG2233. LUCA.
HOGENOMiHOG000117723.
InParanoidiP77328.
PhylomeDBiP77328.

Family and domain databases

InterProiView protein in InterPro
IPR006043. Xant/urac/vitC.
PfamiView protein in Pfam
PF00860. Xan_ur_permease. 1 hit.

Sequencei

Sequence statusi: Complete.

P77328-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNFAVSRES LLSGFQWFFF IFCNTVVVPP TLLSAFQLPQ SSLLTLTQYA
60 70 80 90 100
FLATALACFA QAFCGHRRAI MEGPGGLWWG TILTITLGEA SRGTPINDIA
110 120 130 140 150
TSLAVGIALS GVLTMLIGFS GLGHRLARLF TPSVMVLFML MLGAQLTTIF
160 170 180 190 200
FKGMLGLPFG IADPNFKIQL PPFALSVAVM CLVLAMIIFL PQRFARYGLL
210 220 230 240 250
VGTITGWLLW YFCFPSSHSL SGELHWQWFP LGSGGALSPG IILTAVITGL
260 270 280 290 300
VNISNTYGAI RGTDVFYPQQ GAGNTRYRRS FVATGFMTLI TVPLAVIPFS
310 320 330 340 350
PFVSSIGLLT QTGDYTRRSF IYGSVICLLV ALVPALTRLF CSIPLPVSSA
360 370 380 390 400
VMLVSYLPLL FSALVFSQQI TFTARNIYRL ALPLFVGIFL MALPPVYLQD
410 420 430
LPLTLRPLLS NGLLVGILLA VLMDNLIPWE RIE
Length:433
Mass (Da):47,239
Last modified:December 1, 2000 - v2
Checksum:i0728F25A521B2193
GO

Sequence cautioni

The sequence AAB40265 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89279 Genomic DNA. Translation: AAB93854.1.
U82664 Genomic DNA. Translation: AAB40265.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73615.2.
AP009048 Genomic DNA. Translation: BAE76291.1.
RefSeqiNP_415046.4. NC_000913.3.
WP_001302767.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73615; AAC73615; b0513.
BAE76291; BAE76291; BAE76291.
GeneIDi945131.
KEGGiecj:JW0501.
eco:b0513.
PATRICifig|1411691.4.peg.1765.

Similar proteinsi

Entry informationi

Entry nameiYBBY_ECOLI
AccessioniPrimary (citable) accession number: P77328
Secondary accession number(s): Q2MBR5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: December 1, 2000
Last modified: July 5, 2017
This is version 117 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families