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Protein

Probable ABC transporter permease protein YphD

Gene

yphD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probably part of the binding-protein-dependent transport system YphDEF. Probably responsible for the translocation of the substrate across the membrane.

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YPHD-MONOMER.
ECOL316407:JW2530-MONOMER.

Protein family/group databases

TCDBi3.A.1.2.27. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ABC transporter permease protein YphD
Gene namesi
Name:yphD
Ordered Locus Names:b2546, JW2530
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13465. yphD.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei28 – 4821HelicalSequence analysisAdd
BLAST
Transmembranei63 – 8321HelicalSequence analysisAdd
BLAST
Transmembranei84 – 10421HelicalSequence analysisAdd
BLAST
Transmembranei105 – 12521HelicalSequence analysisAdd
BLAST
Transmembranei131 – 15121HelicalSequence analysisAdd
BLAST
Transmembranei172 – 19221HelicalSequence analysisAdd
BLAST
Transmembranei222 – 24221HelicalSequence analysisAdd
BLAST
Transmembranei251 – 27121HelicalSequence analysisAdd
BLAST
Transmembranei278 – 29821HelicalSequence analysisAdd
BLAST
Transmembranei303 – 32321HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 332332Probable ABC transporter permease protein YphDPRO_0000060264Add
BLAST

Proteomic databases

PaxDbiP77315.
PRIDEiP77315.

Interactioni

Protein-protein interaction databases

BioGridi4261317. 8 interactions.
STRINGi511145.b2546.

Structurei

3D structure databases

ProteinModelPortaliP77315.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CNN. Bacteria.
COG1172. LUCA.
HOGENOMiHOG000212232.
InParanoidiP77315.
KOiK02057.
OMAiITYMISK.
OrthoDBiEOG61P6T8.
PhylomeDBiP77315.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77315-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASSLPLPQ GKSVSLKQFV SRHINEIGLL VVIAILYLVF SLNAPGFISL
60 70 80 90 100
NNQMNVLRDA ATIGIAAWAM TLIIISGEID VSVGPMVAFV SVCLAFLLQF
110 120 130 140 150
EVPLAVACLL VLLLGALMGT LAGVLRGVFN VPSFVATLGL WSALRGMGLF
160 170 180 190 200
MTNALPVPID ENEVLDWLGG QFLGVPVSAL IMIVLFALFV FISRKTAFGR
210 220 230 240 250
SVFAVGGNAT AAQLCGINVR RVRILIFTLS GLLAAVTGIL LAARLGSGNA
260 270 280 290 300
GAANGLEFDV IAAVVVGGTA LSGGRGSLFG TLLGVLVITL IGNGLVLLGI
310 320 330
NSFFQQVVRG VIIVVAVLAN ILLTQRSSKA KR
Length:332
Mass (Da):34,483
Last modified:February 1, 1997 - v1
Checksum:i226C21E6C6C2F719
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75599.1.
AP009048 Genomic DNA. Translation: BAA16448.1.
PIRiA65032.
RefSeqiNP_417041.1. NC_000913.3.
WP_001276670.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75599; AAC75599; b2546.
BAA16448; BAA16448; BAA16448.
GeneIDi949063.
KEGGiecj:JW2530.
eco:b2546.
PATRICi32120489. VBIEscCol129921_2647.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75599.1.
AP009048 Genomic DNA. Translation: BAA16448.1.
PIRiA65032.
RefSeqiNP_417041.1. NC_000913.3.
WP_001276670.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77315.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261317. 8 interactions.
STRINGi511145.b2546.

Protein family/group databases

TCDBi3.A.1.2.27. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP77315.
PRIDEiP77315.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75599; AAC75599; b2546.
BAA16448; BAA16448; BAA16448.
GeneIDi949063.
KEGGiecj:JW2530.
eco:b2546.
PATRICi32120489. VBIEscCol129921_2647.

Organism-specific databases

EchoBASEiEB3238.
EcoGeneiEG13465. yphD.

Phylogenomic databases

eggNOGiENOG4105CNN. Bacteria.
COG1172. LUCA.
HOGENOMiHOG000212232.
InParanoidiP77315.
KOiK02057.
OMAiITYMISK.
OrthoDBiEOG61P6T8.
PhylomeDBiP77315.

Enzyme and pathway databases

BioCyciEcoCyc:YPHD-MONOMER.
ECOL316407:JW2530-MONOMER.

Miscellaneous databases

PROiP77315.

Family and domain databases

InterProiIPR001851. ABC_transp_permease.
[Graphical view]
PfamiPF02653. BPD_transp_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYPHD_ECOLI
AccessioniPrimary (citable) accession number: P77315
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: July 6, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.