ID   YNEJ_ECOLI              Reviewed;         293 AA.
AC   P77309;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   27-MAR-2024, entry version 152.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YneJ;
GN   Name=yneJ; OrderedLocusNames=b1526, JW1519;
OS   Escherichia coli (strain K12).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U00096; AAC74599.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15209.1; -; Genomic_DNA.
DR   PIR; A64907; A64907.
DR   RefSeq; NP_416043.1; NC_000913.3.
DR   RefSeq; WP_000366501.1; NZ_SSZK01000001.1.
DR   AlphaFoldDB; P77309; -.
DR   SMR; P77309; -.
DR   BioGRID; 4261696; 132.
DR   IntAct; P77309; 2.
DR   STRING; 511145.b1526; -.
DR   PaxDb; 511145-b1526; -.
DR   DNASU; 946079; -.
DR   EnsemblBacteria; AAC74599; AAC74599; b1526.
DR   GeneID; 946079; -.
DR   KEGG; ecj:JW1519; -.
DR   KEGG; eco:b1526; -.
DR   PATRIC; fig|1411691.4.peg.740; -.
DR   EchoBASE; EB3579; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_1_6; -.
DR   InParanoid; P77309; -.
DR   OMA; LTTWLIW; -.
DR   OrthoDB; 464481at2; -.
DR   PhylomeDB; P77309; -.
DR   BioCyc; EcoCyc:G6812-MONOMER; -.
DR   PRO; PR:P77309; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR   CDD; cd08442; PBP2_YofA_SoxR_like; 1.
DR   Gene3D; 3.40.190.290; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR   PANTHER; PTHR30126:SF98; HTH-TYPE TRANSCRIPTIONAL REGULATOR NMOR; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..293
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YneJ"
FT                   /id="PRO_0000105808"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..38
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   293 AA;  32483 MW;  F50C3F3237AD923B CRC64;
     MDLTQLEMFN AVAEAGSITQ AAAKVHRVPS NLTTRLRQLE TELGVDLFIR ENQRLRLSPA
     GHNFLRYSQQ ILALVDEARS VVAGDEPQGL FSLGSLESTA AVRIPATLAE FNRRYPKIQF
     SLSTGPSGTM LDGVLEGKLN AAFIDGPINH TAIDGIPVYR EELMIVTPQG YAPVTRASQV
     NGSNIYAFRA NCSYRRHFES WFHADGAAPG TIHEMESYHG MLACVIAGAG IALIPRSMLE
     SMPGHHQVEA WPLAEQWRWL TTWLVWRRGA KTRPLEAFIQ LLDVPDSARQ GYQ
//