P77309 (YNEJ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized HTH-type transcriptional regulator YneJ

Gene names

Name:	yneJ
Ordered Locus Names:	b1526, JW1519

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 HTH lysR-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 293	293	Uncharacterized HTH-type transcriptional regulator YneJ		PRO_0000105808
Regions
	Domain	1 – 58	58	HTH lysR-type
	DNA binding	18 – 38	21	H-T-H motif Potential

Sequences

	Sequence		Length	Mass (Da)
	P77309 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: F50C3F3237AD923B	FASTA	293	32,483
	10 20 30 40 50 60 MDLTQLEMFN AVAEAGSITQ AAAKVHRVPS NLTTRLRQLE TELGVDLFIR ENQRLRLSPA 70 80 90 100 110 120 GHNFLRYSQQ ILALVDEARS VVAGDEPQGL FSLGSLESTA AVRIPATLAE FNRRYPKIQF 130 140 150 160 170 180 SLSTGPSGTM LDGVLEGKLN AAFIDGPINH TAIDGIPVYR EELMIVTPQG YAPVTRASQV 190 200 210 220 230 240 NGSNIYAFRA NCSYRRHFES WFHADGAAPG TIHEMESYHG MLACVIAGAG IALIPRSMLE 250 260 270 280 290 SMPGHHQVEA WPLAEQWRWL TTWLVWRRGA KTRPLEAFIQ LLDVPDSARQ GYQ

References

[1]	"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:363-377(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC74599.1. AP009048 Genomic DNA. Translation: BAA15209.1.
PIR	A64907.
RefSeq	NP_416043.1. NC_000913.2. YP_489789.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P77309.
SMR	P77309. Positions 1-237.
ModBase	Search...
Protein-protein interaction databases
IntAct	P77309. 2 interactions.
STRING	511145.b1526.
Proteomic databases
PaxDb	P77309.
PRIDE	P77309.
Protocols and materials databases
DNASU	946079.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC74599; AAC74599; b1526. BAA15209; BAA15209; BAA15209.
GeneID	12932702. 946079.
KEGG	ecj:Y75_p1501. eco:b1526.
PATRIC	32118350. VBIEscCol129921_1595.
Organism-specific databases
EchoBASE	EB3579.
EcoGene	EG13818. yneJ.
Phylogenomic databases
eggNOG	COG0583.
HOGENOM	HOG000233521.
OMA	YAFRTNC.
ProtClustDB	CLSK866551.
Enzyme and pathway databases
BioCyc	EcoCyc:G6812-MONOMER. ECOL316407:JW1519-MONOMER.
Gene expression databases
Genevestigator	P77309.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
InterPro	IPR005119. LysR_subst-bd. IPR000847. Tscrpt_reg_HTH_LysR. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF00126. HTH_1. 1 hit. PF03466. LysR_substrate. 1 hit. [Graphical view]
PROSITE	PS50931. HTH_LYSR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YNEJ_ECOLI

Accession

Primary (citable) accession number: P77309

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 94 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program