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Protein

Uncharacterized HTH-type transcriptional regulator YagI

Gene

yagI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi25 – 45H-T-H motifPROSITE-ProRule annotationAdd BLAST21

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: GO_Central
  • single-species biofilm formation Source: EcoCyc
  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6144-MONOMER.
ECOL316407:JW0265-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YagI
Gene namesi
Name:yagI
Ordered Locus Names:b0272, JW0265
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13349. yagI.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002017691 – 252Uncharacterized HTH-type transcriptional regulator YagIAdd BLAST252

Proteomic databases

PaxDbiP77300.
PRIDEiP77300.

Interactioni

Protein-protein interaction databases

BioGridi4261498. 8 interactors.
IntActiP77300. 5 interactors.
STRINGi511145.b0272.

Structurei

3D structure databases

ProteinModelPortaliP77300.
SMRiP77300.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 66HTH iclR-typePROSITE-ProRule annotationAdd BLAST63
Domaini81 – 250IclR-EDPROSITE-ProRule annotationAdd BLAST170

Sequence similaritiesi

Contains 1 HTH iclR-type DNA-binding domain.PROSITE-ProRule annotation
Contains 1 iclR-ED (iclR effector binding) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4107HP6. Bacteria.
COG1414. LUCA.
HOGENOMiHOG000107041.
InParanoidiP77300.
OMAiLIAEPHL.
PhylomeDBiP77300.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.30.450.40. 1 hit.
InterProiIPR029016. GAF_dom-like.
IPR014757. Tscrpt_reg_IclR_C.
IPR005471. Tscrpt_reg_IclR_N.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF09339. HTH_IclR. 1 hit.
PF01614. IclR. 1 hit.
[Graphical view]
SMARTiSM00346. HTH_ICLR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF55781. SSF55781. 1 hit.
PROSITEiPS51077. HTH_ICLR. 1 hit.
PS51078. ICLR_ED. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77300-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPIIQSVERA LQILDLFNEQ ATELKITDIS KLMGLSKSTL HSLLKTLQLH
60 70 80 90 100
GYIDQNPENG KYRLGMKLVE RGHFVVGSID IRQKAKGWLT ELSRRTGQTT
110 120 130 140 150
HLGILDGREG VYIEKIEGKL AAIAYSRIGR RLPVHATAIG KVLIAWLGEA
160 170 180 190 200
ELNALLEGYQ YTTFTPATLA SREALMSALA QTREQGYALD SEENEQGVRC
210 220 230 240 250
VAVPVWNHES RVIAALSLST LTSRVDDAEL ANFREQLQQA GLALSRALGY

PA
Length:252
Mass (Da):27,838
Last modified:February 1, 1997 - v1
Checksum:i8FF297AE8FF2E435
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70214 Genomic DNA. Translation: AAB08693.1.
U00096 Genomic DNA. Translation: AAC73375.1.
AP009048 Genomic DNA. Translation: BAE76056.1.
PIRiH64752.
RefSeqiNP_414806.1. NC_000913.3.
WP_001121657.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73375; AAC73375; b0272.
BAE76056; BAE76056; BAE76056.
GeneIDi945016.
KEGGiecj:JW0265.
eco:b0272.
PATRICi32115665. VBIEscCol129921_0276.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70214 Genomic DNA. Translation: AAB08693.1.
U00096 Genomic DNA. Translation: AAC73375.1.
AP009048 Genomic DNA. Translation: BAE76056.1.
PIRiH64752.
RefSeqiNP_414806.1. NC_000913.3.
WP_001121657.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77300.
SMRiP77300.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261498. 8 interactors.
IntActiP77300. 5 interactors.
STRINGi511145.b0272.

Proteomic databases

PaxDbiP77300.
PRIDEiP77300.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73375; AAC73375; b0272.
BAE76056; BAE76056; BAE76056.
GeneIDi945016.
KEGGiecj:JW0265.
eco:b0272.
PATRICi32115665. VBIEscCol129921_0276.

Organism-specific databases

EchoBASEiEB3133.
EcoGeneiEG13349. yagI.

Phylogenomic databases

eggNOGiENOG4107HP6. Bacteria.
COG1414. LUCA.
HOGENOMiHOG000107041.
InParanoidiP77300.
OMAiLIAEPHL.
PhylomeDBiP77300.

Enzyme and pathway databases

BioCyciEcoCyc:G6144-MONOMER.
ECOL316407:JW0265-MONOMER.

Miscellaneous databases

PROiP77300.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.30.450.40. 1 hit.
InterProiIPR029016. GAF_dom-like.
IPR014757. Tscrpt_reg_IclR_C.
IPR005471. Tscrpt_reg_IclR_N.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF09339. HTH_IclR. 1 hit.
PF01614. IclR. 1 hit.
[Graphical view]
SMARTiSM00346. HTH_ICLR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF55781. SSF55781. 1 hit.
PROSITEiPS51077. HTH_ICLR. 1 hit.
PS51078. ICLR_ED. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYAGI_ECOLI
AccessioniPrimary (citable) accession number: P77300
Secondary accession number(s): Q2MCF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.