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Protein

Probable HTH-type transcriptional regulator YgaV

Gene

ygaV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Functions as transcription repressor.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi41 – 60H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G7397-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable HTH-type transcriptional regulator YgaV
Gene namesi
Name:ygaV
Ordered Locus Names:b2667, JW2642
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13524 ygaV

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001606281 – 99Probable HTH-type transcriptional regulator YgaVAdd BLAST99

Proteomic databases

PaxDbiP77295
PRIDEiP77295

Interactioni

Subunit structurei

Homodimer.Curated

Protein-protein interaction databases

BioGridi4259220, 10 interactors
IntActiP77295, 10 interactors
STRINGi316385.ECDH10B_2834

Structurei

Secondary structure

199
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi2 – 7Combined sources6
Helixi8 – 10Combined sources3
Helixi11 – 21Combined sources11
Helixi24 – 33Combined sources10
Beta strandi38 – 40Combined sources3
Helixi41 – 48Combined sources8
Helixi52 – 64Combined sources13
Beta strandi67 – 72Combined sources6
Beta strandi77 – 81Combined sources5
Helixi84 – 97Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3CUOX-ray2.00A/B/C/D1-99[»]
ProteinModelPortaliP77295
SMRiP77295
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP77295

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 99HTH arsR-typePROSITE-ProRule annotationAdd BLAST93

Phylogenomic databases

eggNOGiENOG41080HT Bacteria
COG0640 LUCA
HOGENOMiHOG000144506
InParanoidiP77295
OMAiPKPEPGM
PhylomeDBiP77295

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR001845 HTH_ArsR_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01022 HTH_5, 1 hit
PRINTSiPR00778 HTHARSR
SMARTiView protein in SMART
SM00418 HTH_ARSR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50987 HTH_ARSR_2, 1 hit

Sequencei

Sequence statusi: Complete.

P77295-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTELAQLQAS AEQAAALLKA MSHPKRLLIL CMLSGSPGTS AGELTRITGL
60 70 80 90
SASATSQHLA RMRDEGLIDS QRDAQRILYS IKNEAVNAII ATLKNVYCP
Length:99
Mass (Da):10,596
Last modified:February 1, 1997 - v1
Checksum:i93B9B32C62CC0223
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75714.1
AP009048 Genomic DNA Translation: BAA16530.1
PIRiD65046
RefSeqiNP_417153.1, NC_000913.3
WP_000137280.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75714; AAC75714; b2667
BAA16530; BAA16530; BAA16530
GeneIDi947136
KEGGiecj:JW2642
eco:b2667
PATRICifig|511145.12.peg.2759

Similar proteinsi

Entry informationi

Entry nameiYGAV_ECOLI
AccessioniPrimary (citable) accession number: P77295
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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