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Protein

Bactoprenol glucosyl transferase homolog from prophage CPS-53

Gene

yfdH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in O antigen modification. Catalyzes the transfer of the glucose residue from UDP-glucose to a lipid carrier (By similarity).By similarity

GO - Molecular functioni

  1. transferase activity, transferring glycosyl groups Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciEcoCyc:G7220-MONOMER.
ECOL316407:JW2347-MONOMER.

Protein family/group databases

CAZyiGT2. Glycosyltransferase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Bactoprenol glucosyl transferase homolog from prophage CPS-53 (EC:2.4.1.-)
Gene namesi
Name:yfdH
Ordered Locus Names:b2351, JW2347
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG14132. yfdH.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 227227CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei228 – 24821HelicalSequence AnalysisAdd
BLAST
Topological domaini249 – 26214PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei263 – 28321HelicalSequence AnalysisAdd
BLAST
Topological domaini284 – 30623CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306Bactoprenol glucosyl transferase homolog from prophage CPS-53PRO_0000059194Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP77293.

Interactioni

Protein-protein interaction databases

DIPiDIP-11997N.
IntActiP77293. 1 interaction.
STRINGi511145.b2351.

Structurei

3D structure databases

ProteinModelPortaliP77293.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0463.
HOGENOMiHOG000283247.
InParanoidiP77293.
OMAiMWTYIGL.
OrthoDBiEOG65TRV4.
PhylomeDBiP77293.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR001173. Glyco_trans_2-like.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00535. Glycos_transf_2. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

P77293-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKISLVVPVF NEEEAIPIFY KTVREFEELK SYEVEIVFIN DGSKDATESI
60 70 80 90 100
INALAVSDPL VVPLSFTRNF GKEPALFAGL DHATGDAIIP IDVDLQDPIE
110 120 130 140 150
VIPHLIEKWQ AGADMVLAKR SDRSTDGRLK RKTAEWFYKL HNKISNPKIE
160 170 180 190 200
ENVGDFRLMS RDVVENIKLM PERNLFMKGI LSWVGGKTDI VEYVRAERIA
210 220 230 240 250
GDTKFNGWKL WNLALEGITS FSTFPLRIWT YIGLVVASVA FIYGAWMILD
260 270 280 290 300
TIIFGNAVRG YPSLLVSILF LGGIQMIGIG VLGEYIGRTY IETKKRPKYI

IKRVKK
Length:306
Mass (Da):34,635
Last modified:February 1, 1997 - v1
Checksum:i600411D3D201B4E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75410.1.
AP009048 Genomic DNA. Translation: BAA16210.1.
PIRiD65008.
RefSeqiNP_416852.1. NC_000913.3.
YP_490592.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC75410; AAC75410; b2351.
BAA16210; BAA16210; BAA16210.
GeneIDi12931548.
949098.
KEGGiecj:Y75_p2316.
eco:b2351.
PATRICi32120075. VBIEscCol129921_2446.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75410.1.
AP009048 Genomic DNA. Translation: BAA16210.1.
PIRiD65008.
RefSeqiNP_416852.1. NC_000913.3.
YP_490592.1. NC_007779.1.

3D structure databases

ProteinModelPortaliP77293.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-11997N.
IntActiP77293. 1 interaction.
STRINGi511145.b2351.

Protein family/group databases

CAZyiGT2. Glycosyltransferase Family 2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75410; AAC75410; b2351.
BAA16210; BAA16210; BAA16210.
GeneIDi12931548.
949098.
KEGGiecj:Y75_p2316.
eco:b2351.
PATRICi32120075. VBIEscCol129921_2446.

Organism-specific databases

EchoBASEiEB3884.
EcoGeneiEG14132. yfdH.

Phylogenomic databases

eggNOGiCOG0463.
HOGENOMiHOG000283247.
InParanoidiP77293.
OMAiMWTYIGL.
OrthoDBiEOG65TRV4.
PhylomeDBiP77293.

Enzyme and pathway databases

BioCyciEcoCyc:G7220-MONOMER.
ECOL316407:JW2347-MONOMER.

Miscellaneous databases

PROiP77293.

Gene expression databases

GenevestigatoriP77293.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR001173. Glyco_trans_2-like.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00535. Glycos_transf_2. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiGTRB_ECOLI
AccessioniPrimary (citable) accession number: P77293
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: January 7, 2015
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.