P77280 (YDJJ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjJ
EC=1.-.-.-

Gene names

Name:	ydjJ
Ordered Locus Names:	b1774, JW1763

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 2 zinc ions per subunit By similarity.
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 347	347	Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjJ		PRO_0000160892
Sites
	Metal binding	39	1	Zinc 1; catalytic By similarity
	Metal binding	65	1	Zinc 1; catalytic By similarity
	Metal binding	95	1	Zinc 2 By similarity
	Metal binding	98	1	Zinc 2 By similarity
	Metal binding	101	1	Zinc 2 By similarity
	Metal binding	109	1	Zinc 2 By similarity
	Metal binding	152	1	Zinc 1; catalytic By similarity

Sequences

	Sequence		Length	Mass (Da)
	P77280 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: F8E2172184626A3B	FASTA	347	37,701
	10 20 30 40 50 60 MKNSKAILQV PGTMKIISAE IPVPKEDEVL IKVEYVGICG SDVHGFESGP FIPPKDPNQE 70 80 90 100 110 120 IGLGHECAGT VVAVGSRVRK FKPGDRVNIE PGVPCGHCRY CLEGKYNICP DVDFMATQPN 130 140 150 160 170 180 YRGALTHYLC HPESFTYKLP DNMDTMEGAL VEPAAVGMHA AMLADVKPGK KIIILGAGCI 190 200 210 220 230 240 GLMTLQACKC LGATEIAVVD VLEKRLAMAE QLGATVVING AKEDTIARCQ QFTEDMGADI 250 260 270 280 290 300 VFETAGSAVT VKQAPYLVMR GGKIMIVGTV PGDSAINFLK INREVTIQTV FRYANRYPVT 310 320 330 340 IEAISSGRFD VKSMVTHIYD YRDVQQAFEE SVNNKRDIIK GVIKISD

References

[1]	"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:363-377(1996) [PubMed: 9097039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC74844.1. AP009048 Genomic DNA. Translation: BAA15572.1.
PIR	F64937.
RefSeq	NP_416288.1. NC_000913.2.
3D structure databases
ProteinModelPortal	P77280.
SMR	P77280. Positions 2-347.
ModBase	Search...
Protein-protein interaction databases
IntAct	P77280. 9 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000001375; EBESCP00000001375; EBESCG00000001145. EBESCT00000018042; EBESCP00000017333; EBESCG00000017098.
GeneID	946292.
GenomeReviews	Gene locus JW1763 in contig AP009048_GR. Gene locus b1774 in contig U00096_GR.
KEGG	ecj:JW1763. eco:b1774.
PATRIC	32118859. VBIEscCol129921_1847.
Organism-specific databases
EchoBASE	EB3259.
EcoGene	EG13486. ydjJ.
Phylogenomic databases
eggNOG	COG1063.
GeneTree	EBGT00050000008795.
HOGENOM	HBG753318.
OMA	KCLGATD.
PhylomeDB	P77280.
ProtClustDB	CLSK880192.
Enzyme and pathway databases
BioCyc	EcoCyc:G6961-MONOMER.
Gene expression databases
Genevestigator	P77280.
Family and domain databases
InterPro	IPR013149. ADH_C. IPR013154. ADH_GroES-like. IPR002085. ADH_SF_Zn-type. IPR002328. ADH_Zn_CS. IPR011032. GroES-like. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR11695. ADH_Sf_Zn. 1 hit.
Pfam	PF08240. ADH_N. 1 hit. PF00107. ADH_zinc_N. 1 hit. [Graphical view]
SUPFAM	SSF50129. GroES_like. 1 hit.
PROSITE	PS00059. ADH_ZINC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YDJJ_ECOLI

Accession

Primary (citable) accession number: P77280
Secondary accession number(s): P78174

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program