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Protein

Probable D,D-dipeptide transport ATP-binding protein DdpD

Gene

ddpD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for energy coupling to the transport system.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi42 – 49ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Peptide transport, Protein transport, Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:YDDP-MONOMER.
ECOL316407:JW1479-MONOMER.

Protein family/group databases

TCDBi3.A.1.5.38. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable D,D-dipeptide transport ATP-binding protein DdpD
Gene namesi
Name:ddpD
Synonyms:yddP
Ordered Locus Names:b1484, JW1479
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13787. ddpD.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000931651 – 328Probable D,D-dipeptide transport ATP-binding protein DdpDAdd BLAST328

Proteomic databases

PaxDbiP77268.
PRIDEiP77268.

Expressioni

Inductioni

Induced by RpoS in stationary phase.1 Publication

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (DdpD and DdpF), two transmembrane proteins (DdpB and DdpC) and a solute-binding protein (DdpA).Curated

Protein-protein interaction databases

BioGridi4260962. 121 interactors.
DIPiDIP-11669N.
IntActiP77268. 8 interactors.
STRINGi511145.b1484.

Structurei

3D structure databases

ProteinModelPortaliP77268.
SMRiP77268.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 257ABC transporterPROSITE-ProRule annotationAdd BLAST252

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105C3U. Bacteria.
COG0444. LUCA.
InParanoidiP77268.
KOiK02031.
OMAiACHFAQE.
PhylomeDBiP77268.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013563. Oligopep_ABC_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF08352. oligo_HPY. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01727. oligo_HPY. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77268-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQPVLDIQQ LHLSFPGFNG DVHALNNVSL QINRGEIVGL VGESGSGKSV
60 70 80 90 100
TAMLIMRLLP TGSYCVHRGQ ISLLGEDVLN AREKQLRQWR GARVAMIFQE
110 120 130 140 150
PMTALNPTRR IGLQMMDVIR HHQPISRREA RAKAIDLLEE MQIPDAVEVM
160 170 180 190 200
SRYPFELSGG MRQRVMIALA FSCEPQLIIA DEPTTALDVT VQLQVLRLLK
210 220 230 240 250
HKARASGTAV LFISHDMAVV SQLCDSVYVM YAGSVIESGV TADVIHHPRH
260 270 280 290 300
PYTIGLLQCA PEHGVPRQLL PAIPGTVPNL THLPDGCAFR DRCYAAGAQC
310 320
ENVPALTACG DNNQRCACWY PQQEVISV
Length:328
Mass (Da):36,100
Last modified:February 1, 1997 - v1
Checksum:i76EAFDCAEFED5E6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74557.1.
AP009048 Genomic DNA. Translation: BAA15139.1.
PIRiG64901.
RefSeqiNP_416001.1. NC_000913.3.
WP_000193547.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74557; AAC74557; b1484.
BAA15139; BAA15139; BAA15139.
GeneIDi946002.
KEGGiecj:JW1479.
eco:b1484.
PATRICi32118262. VBIEscCol129921_1551.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74557.1.
AP009048 Genomic DNA. Translation: BAA15139.1.
PIRiG64901.
RefSeqiNP_416001.1. NC_000913.3.
WP_000193547.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77268.
SMRiP77268.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260962. 121 interactors.
DIPiDIP-11669N.
IntActiP77268. 8 interactors.
STRINGi511145.b1484.

Protein family/group databases

TCDBi3.A.1.5.38. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP77268.
PRIDEiP77268.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74557; AAC74557; b1484.
BAA15139; BAA15139; BAA15139.
GeneIDi946002.
KEGGiecj:JW1479.
eco:b1484.
PATRICi32118262. VBIEscCol129921_1551.

Organism-specific databases

EchoBASEiEB3548.
EcoGeneiEG13787. ddpD.

Phylogenomic databases

eggNOGiENOG4105C3U. Bacteria.
COG0444. LUCA.
InParanoidiP77268.
KOiK02031.
OMAiACHFAQE.
PhylomeDBiP77268.

Enzyme and pathway databases

BioCyciEcoCyc:YDDP-MONOMER.
ECOL316407:JW1479-MONOMER.

Miscellaneous databases

PROiP77268.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013563. Oligopep_ABC_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF08352. oligo_HPY. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01727. oligo_HPY. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDDPD_ECOLI
AccessioniPrimary (citable) accession number: P77268
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 127 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.