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Protein

Uncharacterized protein YkgE

Gene

ykgE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G6176-MONOMER.
ECOL316407:JW5041-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YkgE
Gene namesi
Name:ykgE
Ordered Locus Names:b0306, JW5041
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13582. ykgE.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001685691 – 239Uncharacterized protein YkgEAdd BLAST239

Proteomic databases

PaxDbiP77252.
PRIDEiP77252.

Interactioni

Protein-protein interaction databases

BioGridi4262811. 20 interactors.
STRINGi511145.b0306.

Structurei

3D structure databases

ProteinModelPortaliP77252.
SMRiP77252.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LutA/YkgE family.Curated

Phylogenomic databases

eggNOGiENOG4105CHG. Bacteria.
COG0247. LUCA.
HOGENOMiHOG000262113.
InParanoidiP77252.
KOiK18928.
OMAiNSCLMHI.
PhylomeDBiP77252.

Family and domain databases

InterProiIPR004017. Cys_rich_dom.
[Graphical view]
PfamiPF02754. CCG. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77252-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVNFFVTCI GDALKSRMAR DSVLLLEKLG CRVNFPEKQG CCGQPAINSG
60 70 80 90 100
YIKEAIPGMK NLIAALEDND DPIISPAGSC TYAVKSYPTY LADEPEWASR
110 120 130 140 150
AAKVAARMQD LTSFIVNKLG VVDVGASLQG RAVYHPSCSL ARKLGVKDEP
160 170 180 190 200
LTLLKNVRGL ELLTFAEQDT CCGFGGTFSV KMAEISGEMV KEKVAHLMEV
210 220 230
RPEYLIGADV SCLLNISGRL QREGQKVKVM HIAEVLMSR
Length:239
Mass (Da):26,004
Last modified:February 1, 1997 - v1
Checksum:i8CDCC8BBB8228B68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA. Translation: AAB18033.1.
U00096 Genomic DNA. Translation: AAC73409.1.
AP009048 Genomic DNA. Translation: BAE76090.1.
PIRiB64757.
RefSeqiNP_414840.1. NC_000913.3.
WP_001102108.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73409; AAC73409; b0306.
BAE76090; BAE76090; BAE76090.
GeneIDi948438.
KEGGiecj:JW5041.
eco:b0306.
PATRICi32115743. VBIEscCol129921_0314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA. Translation: AAB18033.1.
U00096 Genomic DNA. Translation: AAC73409.1.
AP009048 Genomic DNA. Translation: BAE76090.1.
PIRiB64757.
RefSeqiNP_414840.1. NC_000913.3.
WP_001102108.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77252.
SMRiP77252.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262811. 20 interactors.
STRINGi511145.b0306.

Proteomic databases

PaxDbiP77252.
PRIDEiP77252.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73409; AAC73409; b0306.
BAE76090; BAE76090; BAE76090.
GeneIDi948438.
KEGGiecj:JW5041.
eco:b0306.
PATRICi32115743. VBIEscCol129921_0314.

Organism-specific databases

EchoBASEiEB3352.
EcoGeneiEG13582. ykgE.

Phylogenomic databases

eggNOGiENOG4105CHG. Bacteria.
COG0247. LUCA.
HOGENOMiHOG000262113.
InParanoidiP77252.
KOiK18928.
OMAiNSCLMHI.
PhylomeDBiP77252.

Enzyme and pathway databases

BioCyciEcoCyc:G6176-MONOMER.
ECOL316407:JW5041-MONOMER.

Miscellaneous databases

PROiP77252.

Family and domain databases

InterProiIPR004017. Cys_rich_dom.
[Graphical view]
PfamiPF02754. CCG. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYKGE_ECOLI
AccessioniPrimary (citable) accession number: P77252
Secondary accession number(s): Q2MCB6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

The E.coli ykgEFG operon is a clear homolog of the B.subtilis lutABC operon, however it is not able of restoring L-lactate utilization to the B.subtilis mutant for lutABC operon. Thus, ykgEFG operon may contribute to lactate catabolism in E.coli, but under conditions other than those tested, or alternatively, the ykgEFG operon may be responsible for the catabolism of a metabolite other than (but perhaps related to) lactate in E.coli.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.