P77219 (YAHC_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YahC

Gene names

Name:	yahC
Ordered Locus Names:	b0317, JW0309

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	To E.coli YcdZ.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 165	165	Uncharacterized protein YahC		PRO_0000168574
Regions
	Transmembrane	30 – 50	21	Helical; Potential
	Transmembrane	65 – 85	21	Helical; Potential
	Transmembrane	86 – 106	21	Helical; Potential
	Transmembrane	108 – 128	21	Helical; Potential
	Transmembrane	131 – 151	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P77219 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 78571053F809DC00	FASTA	165	17,311
	10 20 30 40 50 60 MNGLTATGVT VGICAGLWQL VSSHVGLSQG WELLGTIGFV AFCSFYAAGG GKSGFIRSLA 70 80 90 100 110 120 VNYSGMVWAF FAALTAGWLA SVSGLSAFWA SVITTVPFSA VVVWQGRFWL LSFIPGGFLG 130 140 150 160 MTLFFASGMN WTVTLLGFLA GNCVGVISEY GGQKLSEATT KRDGY

References

[1]	"Sequence of minutes 4-25 of Escherichia coli." Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W. Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U73857 Genomic DNA. Translation: AAB18043.1. U00096 Genomic DNA. Translation: AAC73420.1. AP009048 Genomic DNA. Translation: BAE76100.1.
PIR	E64758.
RefSeq	NP_414851.1. NC_000913.2. YP_488612.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P77219.
ModBase	Search...
Protein-protein interaction databases
STRING	511145.b0317.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC73420; AAC73420; b0317. BAE76100; BAE76100; BAE76100.
GeneID	12933811. 947337.
KEGG	ecj:Y75_p0307. eco:b0317.
PATRIC	32115763. VBIEscCol129921_0324.
Organism-specific databases
EchoBASE	EB3357.
EcoGene	EG13587. yahC.
Phylogenomic databases
eggNOG	NOG139834.
HOGENOM	HOG000284435.
OMA	VWASVIT.
ProtClustDB	CLSK879637.
Enzyme and pathway databases
BioCyc	EcoCyc:G6182-MONOMER. ECOL316407:JW0309-MONOMER.
Gene expression databases
Genevestigator	P77219.
Family and domain databases
InterPro	IPR009476. DUF1097. [Graphical view]
Pfam	PF06496. DUF1097. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YAHC_ECOLI

Accession

Primary (citable) accession number: P77219
Secondary accession number(s): Q2MCA6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program