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Protein

Uncharacterized HTH-type transcriptional regulator YdcI

Gene

ydcI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi28 – 4720H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6737-MONOMER.
ECOL316407:JW5226-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YdcI
Gene namesi
Name:ydcI
Ordered Locus Names:b1422, JW5226
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13752. ydcI.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307Uncharacterized HTH-type transcriptional regulator YdcIPRO_0000105783Add
BLAST

Proteomic databases

EPDiP77171.
PaxDbiP77171.
PRIDEiP77171.

Interactioni

Protein-protein interaction databases

BioGridi4260183. 9 interactions.
STRINGi511145.b1422.

Structurei

3D structure databases

ProteinModelPortaliP77171.
SMRiP77171. Positions 11-285.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 6858HTH lysR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105DDW. Bacteria.
ENOG410YQ2R. LUCA.
HOGENOMiHOG000233516.
InParanoidiP77171.
OMAiLCFLEIA.
OrthoDBiEOG686NGM.
PhylomeDBiP77171.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P77171-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKNSLFSQR IRLRHLHTFV AVAQQGTLGR AAETLNLSQP ALSKTLNELE
60 70 80 90 100
QLTGARLFER GRQGAQLTLP GEQFLTHAVR VLDAINTAGR SLHRKEGLNN
110 120 130 140 150
DVVRVGALPT AALGILPSVI GQFHQQQKET TLQVATMSNP MILAGLKTGE
160 170 180 190 200
IDIGIGRMSD PELMTGLNYE LLFLESLKLV VRPNHPLLQE NVTLSRVLEW
210 220 230 240 250
PVVVSPEGTA PRQHSDALVQ SQGCKIPSGC IETLSASLSR QLTVEYDYVW
260 270 280 290 300
FVPSGAVKDD LRHATLVALP VPGHGAGEPI GILTRVDATF SSGCQLMINA

IRKSMPF
Length:307
Mass (Da):33,402
Last modified:December 15, 1998 - v2
Checksum:i186FCA75B38F2A43
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74504.2.
AP009048 Genomic DNA. Translation: BAA15045.2.
PIRiA64894.
RefSeqiNP_415939.2. NC_000913.3.
WP_000414567.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74504; AAC74504; b1422.
BAA15045; BAA15045; BAA15045.
GeneIDi948865.
KEGGiecj:JW5226.
eco:b1422.
PATRICi32118130. VBIEscCol129921_1485.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74504.2.
AP009048 Genomic DNA. Translation: BAA15045.2.
PIRiA64894.
RefSeqiNP_415939.2. NC_000913.3.
WP_000414567.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP77171.
SMRiP77171. Positions 11-285.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260183. 9 interactions.
STRINGi511145.b1422.

Proteomic databases

EPDiP77171.
PaxDbiP77171.
PRIDEiP77171.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74504; AAC74504; b1422.
BAA15045; BAA15045; BAA15045.
GeneIDi948865.
KEGGiecj:JW5226.
eco:b1422.
PATRICi32118130. VBIEscCol129921_1485.

Organism-specific databases

EchoBASEiEB3515.
EcoGeneiEG13752. ydcI.

Phylogenomic databases

eggNOGiENOG4105DDW. Bacteria.
ENOG410YQ2R. LUCA.
HOGENOMiHOG000233516.
InParanoidiP77171.
OMAiLCFLEIA.
OrthoDBiEOG686NGM.
PhylomeDBiP77171.

Enzyme and pathway databases

BioCyciEcoCyc:G6737-MONOMER.
ECOL316407:JW5226-MONOMER.

Miscellaneous databases

PROiP77171.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSiPR00039. HTHLYSR.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYDCI_ECOLI
AccessioniPrimary (citable) accession number: P77171
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: December 15, 1998
Last modified: July 6, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.